Academic Titles & Positions:
MD, Postdoctoral Fellow in Nephrology, Mayo Clinic (USA)
Chief Physician, Associate Professor, Ph.D. Supervisor, Postdoctoral Mentor
Academic Leader of Guangdong Provincial Key Clinical Specialty
Deputy Director of Guangdong Provincial Key Laboratory
Deputy Director of the Precision Medicine Institute, Jinan University
Deputy Director of the Institute of Nephrology and Blood Purification, Jinan University
Outstanding Mid-Career Physician in Guangdong
Guangdong Outstanding Young Medical Talent
Vice Chair, Committee of Nephrology and Blood Purification, National Emergency Medicine Research Center (Emergency General Hospital)
Chair, Blood Purification and Medical Engineering Branch, Guangdong Medical Education Association
Chair, Cell and Biotherapy Branch, Guangdong Women Physicians Association
Vice Chair, Blood Purification and Extracorporeal Circulation Committee, Guangdong Hospital Association
Vice Chair, Blood Purification Branch, Guangdong Biomedical Engineering Society
Vice Chair, Nephrology Branch, Guangdong Women Physicians Association
Review Expert for National Natural Science Foundation (China), Guangdong Provincial Natural Science Foundation, and Zhejiang Provincial Natural Science Foundation

Provincial Awards:
6th Outstanding Physician of Guangdong (Guangdong Health Commission)
First Prize for Scientific and Technological Progress, Ministry of Education
Guangdong Outstanding Medical Achievement Award (Guangdong Department of Science and Technology)
Key Contributor to Second Prize in Science and Technology, Guangdong High-Tech Enterprises Association

National Honors:
2023 National March 8th Red-Banner Pacesetter (All-China Women's Federation)

1. Circulating B Cell-Derived Small RNA Delivered by Extracellular Vesicles: A Dialogue
Mechanism for Long-Range Targeted Renal Mitochondrial Injury in Obesity,Small,2024,(7)
(通讯作者) IF:13.7
2. Carbon modification facilitates piezocatalytic H2O2 production over BiOCl nanosheets:
Correlation between piezoresponse and surface reaction, Applied Catalysis B: Environmental.
2024, 343:123504. (通讯作者) IF:22.1
3. Is reactive oxygen species the only way for cancer inhibition over single atom nanomedicine
Autophagy regulation also works, Chinese Chemical Letters. 2024, 35(6): 109056. (通讯作者)
IF:9.1
4. Calycosin-loaded nanoliposomes as potential nanoplatforms for treatment of diabetic
nephropathy through regulation of mitochondrial respiratory function. Nobiotechnology. 2021
Jun 13;19(1):178 (通讯作者) IF:10.48
5. |Critical roles of cytokine storm and secondary bacterial infection in acute kidney injury
development in COVID-19: A multi-center retrospective cohort study. 2021 Dec;93(12):6641-
6652. (通讯作者) IF:12.7
6. Small RNA-big impact: exosomal miRNAs in mitochondrial dysfunction in various diseases.
RNA Biol 2024. 21(1):1-20. (通讯作者) IF:4.1
7. High-fat diet alters immune cells in spleen, kidney and tumor and impacts the volume growth
of renal cell carcinoma, International Immunopharmacology. 2023 Nov;124(Pt B):110982. (通
讯作者) IF:5.6
8. The Suppression of Sepsis-Induced Kidney Injury Via the Knockout of T Lymphocytes, Heliyon.
2023, Dec 5;10(1):e23311. (通讯作者) IF:4.0
9. Natural Killer Cells, as the Rising Point in Tissues, Are Forgotten in the
Kidney. Biomolecules. 2023 Apr 26;13(5):748. (通讯作者) IF:5.5
10. Pathogenesis of Chronic Kidney Disease Is Closely Bound up with Alzheimer’s Disease, Especially
via the Renin-Angiotensin System, Journal of Clinical Medicine. 2023 Feb 12;12(4):1459. (通讯
作者) IF:3.9
11. The Polarization of M2 Macrophages Can Be Adjusted to Alleviate Renal Injury by
Methylprednisolone in Sepsis-Aki. Arch Biochem Biophys. 2023 Oct 1:747:109738. (通讯作
者) IF:3.9
12. Renal denervation alleviates renal ischemic reperfusion injury-induced acute and chronic
kidney injury in rats partly by modulating miRNAs. Clin Exp Nephrol. 2022 Jan;26(1):13-21.
(通讯作者) IF:2.3
13. The Micro-RNA Cargo of Extracellular Vesicles Released by Human Adipose Tissue-Derived
Mesenchymal Stem Cells Is Modified by Obesity. Front Cell Dev Biol. 2021 May 20;9:660851.
(通讯作者) IF:6.98
14. Differentially Expressed Functional LncRNAs in Human Subjects With Metabolic Syndrome
Reflect a Competing Endogenous RNA Network in Circulating Extracellular Vesicles. Front
Mol Biosci.2021 Aug 17;8:667056. (通讯作者) IF:4.98
15. Metabolic Syndrome Is Associated With Altered mRNA and miRNA Content in Human
Circulating Extracellular Vesicles. Front. Endocrinol. Front Endocrinol (Lausanne). 2021 Aug
12;12:687586. (通讯作者) IF:5.1
16. miR-6869-5p Transported by Plasma Extracellular Vesicles Mediates Renal Tubule Injury and
Renin-Angiotensin System Activation in Obesity. Front. Med. 2021 Sep 8:8:725598. (通讯作
者) IF:5.6
17. Potential role of extracellular vesicles in the pathophysiology of glomerular diseases. Clin Sci
(Lond). 2020 Oct 30;134(20):2741-2754. (通讯作者) IF:5.1
18. Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles
derived from swine and human mesenchymal stem/stromal cells. Cell Commun Signal. 2020
Aug 12;18(1):124. (通讯作者) IF:5.1
19. Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-
derived Mesenchymal Stem Cells Through the P16/MAPK Pathway. Cell Transplant. 2018
Oct;27(10):1495-1503. (第一作者) IF:3.3
20. In vitro study on human umbilical cord mesenchymal stem cells transfected with lentivirus-
mediated hNIS-EGFP dual reporter gene and co-labeled with superparamagnetic iron oxide.
Exp Ther Med. 2018 Sep;16(3):2208-2218. (第一作者) IF:4.0
21. The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles
derived from porcine mesenchymal stem cells. Diabetol Metab Syndr. 2018 Jul 21;10:58 (第
一作者) IF:4.8
22. Obesity-induced mitochondrial dysfunction in porcine adipose tissue-derived mesenchymal
stem cells. J Cell Physiol. 2018 Aug;233(8):5926-5936. (第一作者) IF:5.6
23. The metabolic syndrome alters the miRNA signature of porcine adipose tissue-derived
mesenchymal stem cells. Cytometry A. 2017 Jul 5. (第一作者) IF:3.7
24. External magnetic field promotes homing of magnetized stem cells following subcutaneous
injection, BMC Cell Biology (2017) 18:24 (第一作者)
25. Role of nephrin phosphorylation inducted by dexamethasone and angiotensin II in podocytes，
Molecular Biology Reports，2014.6.01，41(5): 3591~3595 (第一作者) IF:2.8
26. Losartan treating podocyte injury induced by Ang II via downregulation of TRPC6 in
podocytes, Journal of the Renin-Angiotensin-Aldosterone System, 2015.3.14, 1(4):1118~1124
(通讯作者) IF:2.9
27. Analysis of the metabolic properties of maintenance hemodialysis patients with glucose-added
dialysis based on high performance liquid chromatography quadrupole time-of-flight mass
spectrometry, Therapeutics and Clinical Risk Management, 2013.01.01, 9:417~425 (通讯作
者) IF:2.8

1. National Natural Science Foundation of China (NSFC) - General Program, No. 82270756
   Molecular Mechanisms of NK Cell-Derived Extracellular Vesicles in Exacerbating Obesity-Associated Glomerulopathy
   Jan 2023 – Dec 2026 | Principal Investigator | Ongoing

2. Guangdong Natural Science Foundation - General Program, No. 2024A1515011405
   Mechanistic Study of Circulating Extracellular Vesicles on Metabolic Reprogramming of Renal-Resident NK Cells in Obesity-Related Glomerulopathy
   Jan 2024 – Dec 2027 | Principal Investigator | Ongoing

3. Guangdong Provincial Science and Technology Program, No. 2013B040404005
   Post-Medical Care Management for End-Stage Renal Disease
   Sep 2014 – Sep 2016 | Principal Investigator | Completed

4. Guangdong Provincial Science and Technology Program, No. 2016A040403054
   Research on Body Area Network-Based Medical Service Platform for Kidney Diseases
   Jun 2016 – Jun 2019 | Principal Investigator | Completed | Funding: 300,000 yuan

5. Guangdong Natural Science Foundation
   miRNA/MICOS-Mediated Cardiolipin Remodeling: A Novel Mechanism of Mitochondrial Dysfunction in Bone Marrow Endothelial Progenitor Cells in Diabetic Nephropathy
   2018 – 2020 | Principal Investigator | Completed

6. Guangdong Natural Science Foundation, No. 2019A1515010176
   Mechanisms of Integrin-α5β1-Modified ADSCs-EVs Targeting Renal Fibronectin to Repair Early Senescence in Metabolic Syndrome-Associated Kidney Injury
   Jan 2019 – Dec 2022 | Principal Investigator | Completed

7. Guangzhou City-University Joint Funding Program
   Extracellular Vesicles from Adipose-Derived Stem Cells Targeting Mitochondrial Ca²⁺ Homeostasis for Treating Obesity-Induced Podocyte Injury
   2020 – 2023 | Principal Investigator | Completed | Funding: 200,000 yuan

8. Additional Funding
   Other Grants | Total Funding: 600,000 yuan

Academic Leader of Guangdong Provincial Key Clinical Specialty
Deputy Director of Guangdong Provincial Key Laboratory
Deputy Director of the Precision Medicine Institute, Jinan University
Deputy Director of the Institute of Nephrology and Blood Purification, Jinan University
Outstanding Mid-Career Physician in Guangdong
Guangdong Outstanding Young Medical Talent
Vice  Chair, Committee of Nephrology and Blood Purification, National  Emergency Medicine Research Center (Emergency General Hospital)
Chair, Blood Purification and Medical Engineering Branch, Guangdong Medical Education Association
Chair, Cell and Biotherapy Branch, Guangdong Women Physicians Association
Vice Chair, Blood Purification and Extracorporeal Circulation Committee, Guangdong Hospital Association
Vice Chair, Blood Purification Branch, Guangdong Biomedical Engineering Society
Vice Chair, Nephrology Branch, Guangdong Women Physicians Association
Review  Expert for National Natural Science Foundation (China), Guangdong  Provincial Natural Science Foundation, and Zhejiang Provincial Natural  Science Foundation