BasicInformation

头像

Name: Zhouqing

Department: First Clinical Medical College (Affiliated First Hospital)

Gender: female

Post: Executive Deputy Director of Ophthalmology

Career: Professor

Degree: doctor

Graduate School: Jinan University

Tel: 18928903759

Email: kerryzh@163.com

Office Location: 613 Huangpu Avenue West, Tianhe District, Guangzhou City, Guangdong Province

Address: 613 Huangpu Avenue West, Tianhe District, Guangzhou City, Guangdong Province

PostCode: 510630

Fax: no

Honor:

Enrollment

Resume

Professor Zhou Qing, a doctoral supervisor and postdoctoral mentor, is the executive deputy director of the Ophthalmology Department and the director of the Ophthalmology Teaching and Research Section at the First Affiliated Hospital of Jinan University. Currently, she serves as a member of the Fifth Committee of the Ophthalmology Branch of the Chinese Medical Doctor Association, a member of the Youth Committee of the Eleventh Ophthalmology Branch of the Chinese Medical Association, a member of the Ophthalmic Oncology Committee of the Ophthalmology Branch of the Chinese Medical Doctor Association, a standing committee member of the Eleventh Ophthalmology Branch of the Guangdong Medical Association, a standing committee member of the First Committee of the Guangdong Medical Association's Optometry and Myopia Control Branch, and the deputy director of the Ophthalmology Expert Committee of the Guangdong Women's Medical Doctor Association, among others. She is a corresponding editor of the Chinese Journal of Optometry and Visual Science, and an editorial board member of New Medicine, Organ Transplantation, Guangdong Medical Journal, and Chinese Journal of Pathophysiology, as well as a peer reviewer for the National Natural Science Foundation of China. In 2025, she was recognized as an outstanding reviewer of Guangdong Medical Journal.

Professor Zhou Qing has been engaged in ophthalmology for nearly 30 years. She is proficient in strabismus correction surgery, ocular tumor and ocular plastic surgery, as well as the diagnosis and treatment of difficult ophthalmic diseases such as ocular myasthenia gravis and pediatric eye diseases. In 2020, she was awarded the title of Good Doctor of Guangzhou, in 2019, she was honored with the title of Lingnan Famous Doctor, in 2018, she received the title of Outstanding Young and Middle-aged Doctor of Guangdong Province, and in 2024, she was named the first Health Science Popularization Expert of Guangzhou.

In scientific research, I have been engaged in studies on eye tissue regeneration, the application of stem cells in eye tissues, and ocular myasthenia gravis, among others. I have led two projects funded by the National Natural Science Foundation of China, and over ten projects funded by provincial, municipal and university-level research funds. I have published more than 50 papers in domestic and international journals (including SCI papers in Biomater Adv, Stem Cell Res, Exp Eye Res, Expert Opin Ther Targets, J Tissue Eng Regen Med, etc. as the corresponding author), and edited one book titled Zhou Qing's Views on Ocular Myasthenia Gravis 2022. I have also participated in the compilation of several books such as National Advanced Health Professional Technical Qualification Examination Guide Ophthalmology, National Advanced Health Professional Technical Qualification Examination Question Bank Series Ophthalmology Question Bank, Basic Theory and Clinical Practice of Ocular Surface Diseases, Integrated Traditional Chinese and Western Medicine Corneal Diseases, and Ophthalmology Question Bank. I have been granted two patents.

In 2003 and 2005, as a key participant, I was awarded two second prizes for scientific and technological progress in Guangdong Province. In 2004, I received the award for outstanding papers at the National Optometry Specialized Academic Symposium. In 2009, I was honored with the Outstanding Contribution Award for Female Ophthalmologists in Guangdong Province by the Guangdong Medical Association. In 2014, I was awarded the prize for outstanding papers at the Guangdong Ophthalmology Annual Conference. In 2022, I won the second prize in the Academic Exchange Competition of the Guangdong Ophthalmology Annual Conference. In 2024, I received the award for excellence in the Eye Health Sub-competition of the Greater Bay Area Health Science Popularization Competition and the award for excellence in the Guangdong Ophthalmology PDCA Competition. Since 2010, I have trained nearly 20 master's students and 6 doctoral students in ophthalmology.

Education

2004.9 - 2010.6 Doctoral student in Ophthalmology, Jinan University

September 1998 - June 2001: Master's Degree Candidate in Ophthalmology, Jinan University

September 1989 - June 1994: Bachelor of Clinical Medicine, Anhui Medical University

Work Experience

2016.10-now, Professor of Ophthalmology, the First Affiliated Hospital of Jinan University




2014.10-now, Chief physician of Ophthalmology, the First Affiliated Hospital of Jinan University




2007.10-2014.10 Associate Professor of Ophthalmology, The First Affiliated Hospital of Jinan University




2002.10-2007.10, Attending physician of Ophthalmology, the First Affiliated Hospital of Jinan University




2001.7-2002.10, Resident in ophthalmology, the First Affiliated Hospital of Jinan University




1994.6-1998.9, Doctor, Huaibei People's Hospital, Anhui Province


Research Fields

In scientific research, he has been engaged in theresearch of eye tissue regeneration, the application ofstem cells in eye tissue, and eye muscle myastheniagravis. Hosted 2 National Natural Science Foundationprojects; More than 10 provincial, municipal anduniversity-level research fund projects.

Thesis Fields

1: Chen F, Deng J, Luo L, Zhu Y, Dong Y, Yang Y, Zhang R, Chen J, Zhou Q.Crosslinked Decellularized Porcine Pericardium as a Substrate for Conjunctival Reconstruction. Stem Cells Int. 2022 Mar 15; 2022:7571146. doi: 10.1155/2022/7571146. PMID: 35342430; PMCID: PMC8941537.

 

2: Liu CQ, Liu XY, Ouyang PW, Liu Q, Huang XM, Xiao F, Cui YH, Zhou Q, Pan HW. Ferrostatin-1 attenuates pathological angiogenesis in oxygen-induced retinopathy via inhibition of ferroptosis. Exp Eye Res. 2023 Jan;226:109347. doi: 10.1016/j.exer.2022.109347. Epub 2022 Dec 9. PMID: 36502924.

 

3: Chen F, Li C, Liu J, Dong Y, Chen J, Zhou Q. Crosslinked modified decellularized rabbit conjunctival stroma for reconstruction of tissue-engineered conjunctiva in vitro. Biomed Mater. 2023 Nov 9;19(1). doi: 10.1088/1748-605X/ad08e0. PMID: 37917998.

 

4: Mu Y, Huang X, Yang Y, Huang Z, Chen J, Li S, Dong Y, Chen F, Zhang R, Chen J, Feng H, Zhou Q. Study of serum exosome miRNA as a biomarker for early onset adult ocular myasthenia gravis. Gene. 2024 Feb 20;896:148034. doi:10.1016/j.gene.2023.148034. Epub 2023 Nov 25. PMID: 38013129.

 

5: Jiang MM, Zhou Q, Liu XY, Shi CZ, Chen J, Huang XH. Structural and functional brain changes in early- and mid-stage primary open-angle glaucoma using voxel-based morphometry and functional magnetic resonance imaging. Medicine (Baltimore). 2017 Mar;96(9):e6139. doi: 10.1097/MD.0000000000006139. PMID:28248867; PMCID: PMC5340440.

 

6: Xu L, Wang H, Luo L, Deng J, Chen F, Wang Y, Tang J, Wu Z, Zhou Q, Chen J.Aspartic acid and epidermal growth factor modified decellularized rabbit conjunctiva for conjunctival reconstruction. Biomater Adv. 2022 Dec;143:213164.doi: 10.1016/j.bioadv.2022.213164. Epub 2022 Oct 19. PMID: 36343391.

 

7: Mu Y, Xu W, Liu J, Wang Y, Chen J, Zhou Q. Mesenchymal stem cells moderate experimental autoimmune uveitis by dynamic regulating Th17 and Breg cells response. J Tissue Eng Regen Med. 2022 Jan;16(1):26-35. doi: 10.1002/term.3259.Epub 2021 Oct 27. PMID: 34674378.

 

8: Mu Y, Qin X, Yao N, Zhang D, Yang Y, Huang Z, Chen F, Liu C, Dong Y, Zhang R, Chen J, Zhou Q. Single Center to Evaluate and Compare Anisometropic Amblyopia in Adults Using Blood Oxygenation Level-Dependent Functional Magnetic Resonance Imaging and Diffusion Kurtosis Imaging. Med Sci Monit. 2022 Sep 12;28:e937880.doi: 10.12659/MSM.937880. PMID: 36089755; PMCID: PMC9479661.

 

9: Zhu Y, Li C, Shuai R, Huang Z, Chen F, Wang Y, Zhou Q, Chen J. Experimental study of the mechanism of induction of conjunctival goblet cell hyperexpression using CHIR-99021 in vitro. Biochem Biophys Res Commun. 2023 Aug 6;668:104-110.doi: 10.1016/j.bbrc.2023.05.054. Epub 2023 May 23. PMID: 37245290.

 

10: Chen F, Tang J, Zhou Q. Bilateral idiopathic orbital pseudotumour in a child: a case report. BMC Ophthalmol. 2020 Nov 16;20(1):449. doi:10.1186/s12886-020-01718-0. PMID: 33198680; PMCID: PMC7670728.

 

11: Shen S, Liu X, Chen J, Yang C, Shi C, Zhou Q. A cerebral arteriovenous malformation mistakenly diagnosed as dry eye and glaucoma: a case report. BMC Ophthalmol. 2019 Jul 12;19(1):148. doi: 10.1186/s12886-019-1160-8. PMID:31299930; PMCID: PMC6624932.

 

12: Zhu X, Lin X, Xu Y, Li N, Zhou Q, Sun X, Li Y. Effect of Dual Endothelin Receptor Antagonist on a Retinal Degeneration Animal Model by Regulating Choroidal Microvascular Morphology. J Ophthalmol. 2021 Nov 19;2021:5688300. doi:10.1155/2021/5688300. PMID: 34840823; PMCID: PMC8626175.

 

13: Wang WJ, Chen J, Zhang XL, Yao M, Liu XY, Zhou Q, Qu YX. Bevacizumab versus ranibizumab for neovascular age-related macular degeneration: a Meta-analysis.Int J Ophthalmol. 2015 Feb 18;8(1):138-47. doi:10.3980/j.issn.2222-3959.2015.01.26. PMID: 25709924; PMCID: PMC4325258.

 

14: Hao XN, Wang WJ, Chen J, Zhou Q, Qu YX, Liu XY, Xu W. Effects of resveratrol on ARPE-19 cell proliferation and migration <i>via</i> regulating the expression of proliferating cell nuclear antigen, P21, P27 and p38MAPK/MMP-9. Int J Ophthalmol. 2016 Dec 18;9(12):1725-1731. doi: 10.18240/ijo.2016.12.04. PMID:28003970; PMCID: PMC5154983.

 

15: Chen F, Wang T, Yang Y, Huang Z, Dong Y, Zhang R, Chen J, Zhou Q. Generation of an induced pluripotent stem cell line (SYSUSCi001-A) from a congenital cataract patient carrying heterozygous mutations in BFSP1 and RHO. Stem Cell Res. 2022 Mar;59:102644. doi: 10.1016/j.scr.2021.102644. Epub 2021 Dec 28. PMID:34995847.

 

16: Yao M, Chen J, Yang XX, Zhang XL, Ji QS, Zhou Q, Xu JT. Differentiation of human amniotic epithelial cells into corneal epithelial-like cells in vitro. Int J Ophthalmol. 2013 Oct 18;6(5):564-72. doi: 10.3980/j.issn.2222-3959.2013.05.02. PMID: 24195026; PMCID: PMC3808898.

 

17: Zhang XL, Chen J, Zhang RJ, Wang WJ, Zhou Q, Qin XY. Intravitreal triamcinolone versus intravitreal bevacizumab for diabetic macular edema: a meta-analysis. Int J Ophthalmol. 2013 Aug 18;6(4):546-52. doi:10.3980/j.issn.2222-3959.2013.04.26. PMID: 23991395; PMCID: PMC3755320.

 

18: Zhou Q, Liu XY, Ruan YX, Wang L, Jiang MM, Wu J, Chen J. Construction of corneal epithelium with human amniotic epithelial cells and repair of limbal deficiency in rabbit models. Hum Cell. 2015 Jan;28(1):22-36. doi:10.1007/s13577-014-0099-6. Epub 2014 Aug 19. PMID: 25134797.

 

19: Yang XX, Chen J, Zhou Q, Guo XY, Xiao P, Wu J, Xu JT. Troglitazone induced apoptosis of human pterygium fibroblasts through a mitochondrial-dependent pathway. Int J Ophthalmol. 2011;4(2):143-6. doi:10.3980/j.issn.2222-3959.2011.02.06. Epub 2011 Apr 18. PMID: 22553629; PMCID:PMC3340713.

 

20: Liu XY, Chen J, Zhou Q, Wu J, Zhang XL, Wang L, Qin XY. In vitro tissue engineering of lamellar cornea using human amniotic epithelial cells and rabbit cornea stroma. Int J Ophthalmol. 2013 Aug 18;6(4):425-9. doi:10.3980/j.issn.2222-3959.2013.04.03. PMID: 23991372; PMCID: PMC3755297.


21:Zeng J, Cao XF, Chen J, Liu ZP, Lyu J, Zhou Q. Assessment of prognostic factors in patients with primary ocular adnexal lymphoma when considering competing risk elements. Clin Exp Ophthalmol. 2024 Dec;52(9):991-1002. doi: 10.1111/ceo.14427

22:Mu Y, Huang X, Yang Y, Huang Z, Chen J, Li S, Dong Y, Chen F, Zhang R, Chen J, Feng H, Zhou Q. Corrigendum to Study of serum exosome miRNA as a biomarker for early onset adult ouclar myasthenia gravis [Gene 896 (2024) 148034]. Gene. 2024 Jul 30;917:148440. doi: 10.1016/j.gene.2024.148440

 

23:Lee Y, Lee L, Zhang L, Zhou Q. Association between fatty acid intake and age-related macular degeneration: a meta-analysis. Front Nutr. 2024 Jun 26;11:1403987. doi: 10.3389/fnut.2024.1403987

 

24:Cao X, Zeng J, Ou Y, Chen J, Lyu J, Zhou Q. A prognostic nomogram for the cancer-specific survival rate of choroidal melanoma using the Surveillance, Epidemiology, and End Results database. Front Med (Lausanne). 2024 May 16;11:1392336. doi: 10.3389/fmed.2024.1392336

 

25:Cai Y, Cheng Z, Yang Y, Xu B, Feng Q, Liu X, Chen J, Zhou Q. Differentiation and characterization of non-thymomatous ocular myasthenia gravis children with CT. Acta Neurol Belg. 2024 Oct 30. doi: 10.1007/s13760-024-02669-9


Publications

Chief editor of Eye muscle Myasthenia gravis Zhou Qing2022 Viewpoint 1, participated in the compilation ofGuide Ophthalmology for National Advanced HealthProfessional Technical Qualification Examination'Ophthalmology Exercise Collection of NationaAdvanced Health Professional Technical QualificationExamination Series, Basic Theory and Clinic of eyeSurface Diseases, Corneology of Traditional Chineseand Western Medicine, Ophthalmology ExerciseCollection and other books

Undertake the subject

1. A multicenter randomized controlled study comparing the safety and efficacy of local treatment with rituximab and radiotherapy at the affected site for ocular adnexal MALT lymphoma from June 2023 to present, conducted by a sub center at the school level

2. From January 2019 to December 2022, HAEC was responsible for the dynamic three-dimensional construction of conjunctival grafts from decellularized conjunctival matrix and their in vivo transformation mechanisms (at the national level)

3. From March 2014 to March 2017, I was in charge of the research on stem cell therapy for autoimmune related eye diseases at the Guangzhou municipal level

4. 2012.1-2014.12 Human Amniotic Epithelial Cell Induced Differentiation Tissue Engineering Conjunctival Reconstruction (National Level) Hosted

5. Functional Imaging Study on Visual Developmental Plasticity of Adult Patients with Refractive Amblyopia from January 2010 to December 2011 (Guangdong Province level)

6. From January 2009 to December 2011, participated in the construction of tissue-engineered corneal epithelium using human amniotic epithelial cells (national level)

7. Research on inducing human amniotic epithelial cells to differentiate into corneal epithelium for corneal reconstruction from June 2007 to June 2009 (Guangdong Province level)

8. Study on the plasticity of visual cortex neurons at different stages of visual development in amblyopia rats from July 2003 to June 2005 (led by Guangdong Provincial)


Patent for invention

National invention patent: A carrier free cell sheet and its preparation method and application, authorization number: ZL201310611198.2;

National invention patent: A stem cell niche and its preparation method and application, authorization number: ZL201510260768.7;

National invention patent: Cardiac patch with decellularized biofilm as carrier, preparation method and application, authorization number: ZL201410620738.8.

National invention patent: A stem cell extracellular vesicle patch and its preparation method and application, application number: 201510260758.3;

National invention patent: A decellularized matrix with natural levels of glycosaminoglycans and its preparation and application, application number: 201510260705.1;


Open Course

Undergraduate course "Ophthalmology"

Master course "Ophthalmology"

Doctoral course "New Developments in Ophthalmology"


Honor

Social Position

Currently serving as a member of the 5th Committee of the Ophthalmology Branch of the Chinese Medical Association, a member of the Youth Committee of the 11th Ophthalmology Branch of the Chinese Medical Association, a member of the Eye Tumor Special Committee of the Ophthalmology Branch of the Chinese Medical Association, an executive member of the 11th Committee of the Ophthalmology Branch of the Guangdong Medical Association, an executive member of the 1st Committee of the Optometry and Myopia Prevention and Control Branch of the Guangdong Medical Association, and a vice chairman of the Ophthalmology Expert Committee of the Guangdong Women's Medical Association. Serving as a communication editor for the Chinese Journal of Ophthalmology and Visual Science, an editorial board member for journals such as New Medicine, Organ Transplantation, Guangdong Medicine, and Chinese Journal of Pathophysiology, and a peer-reviewed expert for the National Natural Science Foundation of China. Excellent Reviewer Expert of Guangdong Medical Journal in 2025