Dr. Xian-Hui He is a professor in the Department of Immunobiology at Jinan University (Guangzhou, China). He got his bachelor from Xiamen University, received his Ph.D. from The Chinese University of Hong Kong (1999) and Master of Science from Shanghai Institute of Biochemistry (now Shanghai Institute of Biochemistry and Cell Biology) (1990). After his postdoc training (2001), he became a faculty member of the Institute of Tissue  Transplantation and Immunology (Department of Immunobiology). His current interest is focused on the relationship between autophagy and immune responses as well as the roles of the histone deacetylase in immune cells. He is also interested in the mechanism of immunomodulatory effects of natural products from herbal plants. He has served as a member of the editorial board of Acta Biochimica et Biophysica Sinica (a famous SCI-indexed journal in China) since 2006.

1986/7, Bachelor degree, Department of Biology,Xiamen University

1990/10, Master of Science, Shanghai Institute of Biochemistry (now Shanghai Institute of Biochemistry and Cell Biology)

1999/3, Ph.D., The Chinese University of Hong Kong

[1] Yi Liu#, Yan-Yun Jing#, Chen-Ying Zeng#, Chen-Guang Li, Li-Hui Xu, Liang Yan, Wen-Jing Bai, Qing-Bing Zha, Dong-Yun Ouyang, Xian-Hui He*. Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis, Front Pharmacol, 2018, 8:975. (2016 IF=4.400)

[2] Chen-Guang Li#, Liang Yan#, Feng-Yi Mai#, Zi-Jian Shi, Li-Hui Xu, Yan-Yun Jing, Qing-Bing Zha, Dong-Yun Ouyang, Xian-Hui He*, Baicalin Inhibits NOD-Like Receptor Family, Pyrin Containing Domain 3 Inflammasome Activation in Murine Macrophages by Augmenting Protein Kinase A Signaling, Front Immunol, 2017, 8:1409. (2016 IF=6.429)

[3] Qiu-Ru Lin#, Chen-Guang Li#, Qing-Bing Zha#, Li-Hui Xu, Hao Pan, Gao-Xiang Zhao, Dong-Yun Ouyang*, Xian-Hui He*, Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway, Toxicol Appl Pharmacol, 2016, 292: 56-64. (2016 IF=3.791)

[4] Gao-Xiang Zhao#, Li-Hui Xu#, Hao Pan, Qiu-Ru Lin, Mei-Yun Huang, Ji-Ye Cai, Dong-Yun Ouyang*, Xian-Hui He*, The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling, Oncotarget, 2015, 6(36): 38952-38966.

[5] Dong-Yun Ouyang, Li-Hui Xu, Xian-Hui He*, Yan-Ting Zhang, Long-Hui Zeng, Ji-Ye Cai, Shuai Ren, Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5, Autophagy, 2013, 9(1): 20-32. (2013 IF=11.423)

Cellular and Molecular Immunology

 Member of the editorial board for ABBS.