BasicInformation

头像

Name: Sunxuesong

Department: Biochemistry and Molecular Biology

Organization:

Gender: female

Post: Professor

Career:

Degree: Doctor

Graduate School: The University of Hong Kong

Tel:

Email:

Office Location:

Address:

PostCode:

Fax:

Honor:

Enrollment

Resume

2011- present: Professor, Jinan University

2008-2011:  Associate professor,  Jinan University

2007-2008:  Postdoctor

Education

1995-1999: Bacheolar, Nankai University

1999-2002: Master,    Nankai University

2003-2006: Doctr,     The University of Hong Kong

Work Experience

2011- present: Professor, Jinan University

2008-2011:Associate professor,Jinan University

2007-2008:Postdoctor, The University of Hong Kong

Research Fields

Thesis Fields

 

1.     Dong, Y.;  Miao, X.;  Zheng, Y. D.;  Liu, J.;  He, Q. Y.;  Ge, R.; Sun, X., Ciprofloxacin-Resistant Staphylococcus aureus Displays Enhanced Resistance and Virulence in Iron-Restricted Conditions. J Proteome Res 2021,20 (5), 2839-2850.

2.     Zheng, Y. D.;  Pan, Y.;  He, K.;  Li, N.;  Yang, D.;  Du, G. F.;  Ge, R.;  He, Q. Y.; Sun, X., SPD_1495 Contributes to Capsular Polysaccharide Synthesis and Virulence in Streptococcus pneumoniae. mSystems 2020,5 (1).

3.     Han, J.;  Yi, S.;  Zhao, X.;  Zheng, Y.;  Yang, D.;  Du, G.;  Yang, X. Y.;  He, Q. Y.; Sun, X., Improved SILAC method for double labeling of bacterial proteome. J Proteomics 2019,194, 89-98.

4.     Du, G. F.;  Zheng, Y. D.;  Chen, J.;  He, Q. Y.; Sun, X., Novel Mechanistic Insights into Bacterial Fluoroquinolone Resistance. J Proteome Res 2019,18 (11), 3955-3966.

5.     Miao, X.;  He, J.;  Zhang, L.;  Zhao, X.;  Ge, R.;  He, Q. Y.; Sun, X., A Novel Iron Transporter SPD_1590 in Streptococcus pneumoniae Contributing to Bacterial Virulence Properties. Front Microbiol 2018,9, 1624.

6.     Liu, Y. T.;  Pan, Y.;  Lai, F.;  Yin, X. F.;  Ge, R.;  He, Q. Y.; Sun, X., Comprehensive analysis of the lysine acetylome and its potential regulatory roles in the virulence of Streptococcus pneumoniae. J Proteomics 2018,176, 46-55.

7.     Cao, K.;  Li, N.;  Wang, H.;  Cao, X.;  He, J.;  Zhang, B.;  He, Q. Y.;  Zhang, G.; Sun, X., Two zinc-binding domains in the transporter AdcA from Streptococcus pyogenes facilitate high-affinity binding and fast transport of zinc. J Biol Chem 2018,293 (16), 6075-6089.

8.     Ge, R.; Sun, X., Iron acquisition and regulation systems in Streptococcus species. Metallomics : integrated biometal science 2014,6 (5), 996-1003.

9.     Sun, X.;  Yu, G.;  Xu, Q.;  Li, N.;  Xiao, C.;  Yin, X.;  Cao, K.;  Han, J.; He, Q. Y., Putative cobalt- and nickel-binding proteins and motifs in Streptococcus pneumoniae. Metallomics : integrated biometal science 2013,5 (7), 928-35.

10.   Cao, X.;  Guo, Z.;  Wang, H.;  Dong, Y.;  Lu, S.;  He, Q. Y.;  Sun, X.; Zhang, G., Autoactivation of Translation Causes the Bloom of Prorocentrum donghaiense in Harmful Algal Blooms. J Proteome Res 2021,20 (6), 3179-3187.

11.   Yang, D. H.;  Liu, S.;  Cao, L.;  Zheng, Y. D.;  Huang, J. F.;  Ge, R.;  He, Q. Y.; Sun, X., Quantitative secretome analysis of polymyxin B resistance in Escherichia coli. Biochem Biophys Res Commun 2020,530 (1), 307-313.

12.   Yang, X. Y.;  Li, N.;  Xu, J. Y.;  Sun, X.; He, Q. Y., Lipoprotein SPD_1609 of Streptococcus pneumoniae Promotes Adherence and Invasion to Epithelial Cells Contributing to Bacterial Virulence. Front Microbiol 2019,10, 1769.

13.   Shi, T.;  Wei, Q.;  Wang, Z.;  Zhang, G.;  Sun, X.;  He, Q.-Y.; Fey, P. D., Photocatalytic Protein Damage by Silver Nanoparticles Circumvents Bacterial Stress Response and Multidrug Resistance. mSphere 2019,4 (3).

14.   Cao, K.;  Zhang, J.;  Miao, X. Y.;  Wei, Q. X.;  Zhao, X. L.;  He, Q. Y.; Sun, X., Evolution and molecular mechanism of PitAs in iron transport of Streptococcus species. J Inorg Biochem 2018,182, 113-123.

15.   Cao, K.;  Lai, F.;  Zhao, X. L.;  Wei, Q. X.;  Miao, X. Y.;  Ge, R.;  He, Q. Y.; Sun, X., The mechanism of iron-compensation for manganese deficiency of Streptococcus pneumoniae. J Proteomics 2018,184, 62-70.

16.   Zhang, L.;  Li, N.;  Cao, K.;  Yang, X. Y.;  Zeng, G.;  Sun, X.; He, Q. Y., Crucial residue Trp158 of lipoprotein PiaA stabilizes the ferrichrome-PiaA complex in Streptococcus pneumoniae. J Inorg Biochem 2017,167, 150-156.

17.   Yang, X. Y.;  He, K.;  Du, G.;  Wu, X.;  Yu, G.;  Pan, Y.;  Zhang, G.;  Sun, X.; He, Q. Y., Integrated Translatomics with Proteomics to Identify Novel Iron-Transporting Proteins in Streptococcus pneumoniae. Front Microbiol 2016,7, 78.

18.   Yang, X. Y.;  Zhang, L.;  Liu, J.;  Li, N.;  Yu, G.;  Cao, K.;  Han, J.;  Zeng, G.;  Pan, Y.;  Sun, X.; He, Q. Y., Proteomic analysis on the antibacterial activity of a Ru(II) complex against Streptococcus pneumoniae. J Proteomics 2015,115, 107-16.

19.   Guo, Z.;  Han, J.;  Yang, X. Y.;  Cao, K.;  He, K.;  Du, G.;  Zeng, G.;  Zhang, L.;  Yu, G.;  Sun, Z.;  He, Q. Y.; Sun, X., Proteomic analysis of the copper resistance of Streptococcus pneumoniae. Metallomics : integrated biometal science 2015.

20.   Yang, X. Y.;  Zhang, L.;  Liu, J.;  Li, N.;  Yu, G.;  Cao, K.;  Han, J.;  Zeng, G.;  Pan, Y.;  Sun, X.; He, Q. Y., Proteomic analysis on the antibacterial activity of a Ru(II) complex against Streptococcus pneumoniae. J Proteomics 2014,115C, 107-116.

21.   Yang, X. Y.;  Sun, B.;  Zhang, L.;  Li, N.;  Han, J.;  Zhang, J.;  Sun, X.; He, Q. Y., Chemical interference with iron transport systems to suppress bacterial growth of Streptococcus pneumoniae. PloS one 2014,9 (8), e105953.

22.   Wang, N.;  Zhang, J.;  Zhang, L.;  Yang, X. Y.;  Li, N.;  Yu, G.;  Han, J.;  Cao, K.;  Guo, Z.;  Sun, X.; He, Q. Y., Proteomic analysis of putative heme-binding proteins in Streptococcus pyogenes. Metallomics : integrated biometal science 2014,6 (8), 1451-9.

23.   Li, N.;  Yang, X. Y.;  Guo, Z.;  Zhang, J.;  Cao, K.;  Han, J.;  Zhang, G.;  Liu, L.;  Sun, X.; He, Q. Y., Varied metal-binding properties of lipoprotein PsaA in Streptococcus pneumoniae. J Biol Inorg Chem 2014,19 (6), 829-38.

24.   Li, H.;  Li, N.;  Xu, Q.;  Xiao, C.;  Wang, H.;  Guo, Z.;  Zhang, J.;  Sun, X.; He, Q. Y., Lipoprotein FtsB in Streptococcus pyogenes binds ferrichrome in two steps with residues Tyr137 and Trp204 as critical ligands. PloS one 2013,8 (6), e65682.

25.   Yang, X. Y.;  Lu, J.;  Sun, X.; He, Q. Y., Application of subproteomics in the characterization of Gram-positive bacteria. J Proteomics 2011.

 


Publications

Undertake the subject

Patent for invention

Open Course

Honor

Social Position