姓名： 李红

性别：女

学历/学位：研究生/博士

职称：教授博士生导师

职务：人工器官及材料教育部工程研究中心主任

教学岗位： 材料科学与工程

专业所属学科： 材料科学与工程

研究领域： 生物材料

研究方向： 硬组织修复材料和组织工程、纳米材料、无机有机杂化材料

现任人工器官及材料教育部工程研究中心主任。中国生物医学工程学会生物材料分会委员副主任委员，中国生物材料学会产学研委员会委员，中国生物材料学会生物陶瓷分会委员。长期从事生物材料与组织工程的研究，在该领域主持国家自然科学基金面上项目多项，参与和主持了国家863 计划项目，省部级科研项目等多项，获省部级奖励2项。在组织修复和口腔修复材料方面有长期的研究积累，在各类等高水平学术期刊上发表了100余篇SCI 收录研究论文，著有专著《生物矿化与组织修复》获。近年来在组织修复方面开展了产学研工作，与企业合作开发了一系列相关产品。

1997至2002年 四川大学无机材料系，研究生，获生物医学工程博士学位

1986至1990年 武汉工业大学材料科学与工程系，本科

2002年至今 暨南大学历任讲师、副教授、教授，理工学院研究生办公室主任，化学与材料学院副院长

2009至2010年 美国Clemson Univ.，访问学者

2014至2015年 美国Virginia Commonwealth Univ.,访问学者

1990至1997年 中国工程物理研究院材料所，历任助理工程师、工程师

   硬组织修复材料和组织工程、纳米材料、无机有机杂化材料

1.         Hong Qu, Lifeng Hang , Yanzhao Diao , Haiying Wang, Laiping Fang , Wangzi Liu , Jinwu Liu , Hui Sun , Jizhuang Wang , Xianwei Meng*, Hong Li*, Guihua Jiang*.  Mn-doped MOF nanoparticles mitigating hypoxia via in-situ substitution strategy for dual-imaging guided combination treatment of microwave dynamic therapy and chemotherapy ，Journal of Colloid and Interface Science 685 (2025) 912–926 . https://doi.org/10.1016/j.jcis.2025.01.202

2.         Shuyun Zhang，Dengjian Qu，Bowen Luo，Lichen Wang，Hong Li*，Hongjun Wang*. Regulation of Osteogenic Differentiation of hBMSCs by the Overlay Angles of Bone Lamellae-like Matrices. ACS Appl. Mater. Interfaces 2024, 16, 42, 56801–56814

3.         Wangzi Liu, Zhilin Huang, Xiaohui Chen, Shan Ding, Qi Xiang, Yadong Huang, Hong Li*. Human collagen sequence polypeptides mediated biomineralization and its molecular mechanism. Journal of the Mechanical Behavior of Biomedical Materials, 2024, 158, 106687.

4.         Xiaohui Chen, Zhilin Huang, Shuyun Zhang* and Hong Li *. Assembled collagen films modified using polyacrylic acid with improved mechanical properties via mineralization. J. Mater. Chem. B, 2024, 12, 6643

5.         Hong Qu , Yuping Zeng  , Lifeng Hang , Jin Fang a,c , Hui Sun , Hong Li d,**, Guihua Jiang *. Simultaneously acquired rSUV and rCBF of 18F-FDG/MRI in peritumoral brain zone can help to differentiate the grade of glioma. Meta-Radiology 1 (2023) 100020

6.         Yu Zhou, Baoyong Xu, Pan Zhou, Xiaohui Chen, Genlong Jiao, Hong Li*. Gold@mesoporous polydopamine nanoparticles modified self-healing hydrogel for sport-injuring therapy. International Journal of Biological Macromolecules, 2023, 127441,

7.         C. Wang, Z. Huang, Z. Huang, L. Feng and H. Li*, In situ cyclodextrin metal-organic framework/electrospun composite fibers with biosafety for volatile organic compounds removals. J. Mater. Chem. B,, 2023,11, 6603-6611  DOI: 10.1039/D3TB00659J.

8.         Xiaomu Xu, Qiong Wu, Longfei Tan, Xianwei Men, Yue Huang, and Hong Li*. Biomimetic Metal−Chalcogenide Agents Enable Synergistic Cancer Therapy via Microwave Thermal-Dynamic Therapy and Immune Cell Activation. ACS Applied Materials & interfaces. 2023, 15, 42182-42195

9.         Chuang Guo, Jiacheng Wu, Yiming Zeng, and Hong Li* Construction of 3D Bioprinting of HAP/Collagen Scaffold in Gelation Bath for Bone Tissue Engineering. Regenerative Biomaterials, 2023(10), rbad067

10.      Fu Qingyun, Guo Zhenzhao, Bo Dongyin, Huang Ke, Su Ziyu, Jin Weihong, Yu Zhentao*, Xu Shulan*, Li Hong*. Multi-drug delivery and osteogenic performance of β-tricalcium phosphate/alginate composite microspheres, International Journal of Polymeric Materials and Polymeric Biomaterials.2023.2250049

11.      Huang Zhilin, Wang Chucheng, Chen Xiaohui, Ding Shan, Xiang Qi, Xie Mo, Huang Yadong, Li Hong*. Regulation of recombinant humanized collagen on HAP growth and its molecule simulation. RSC ADVANCES, (2023).13(37),26031-26040.

12.      Hongbo Yu, Xiaomu Xu, Zheng Xie, Xiuhong Huang, Licheng Lin, Yanpeng Jiao,* and Hong Li*. High-Efficiency Near-Infrared Light Responsive Antibacterial System for Synergistic Ablation of Bacteria and Biofilm. ACS Applied Materials & Interfaces. 2022, 14, 32, 36947-36956

13.      Shuyun Zhang, Xueshi Luo, Chuang Guo, Ke Huang, Ding Shan, Lihua Li*, Changren Zhou, Hong Li*. Tissue engineered bone via templated hBMSCs mineralization and its application for bone repairing. Biomaterials Advances. 2022, 30, 212937

14.      Shimei Li , Zengzhen Chen , Longfei Tan **, Qiong Wu， Xiangling Ren，Changhui Fu , Meng Niu , Hong Li ***, Xianwei Meng ,* MOF@COF nanocapsule for the enhanced microwave thermal-dynamic therapy and anti-angiogenesis of colorectal cancer. Biomaterials, 283(2022) 121472-121484

15.      Hongbo Yu, Yi Wan, Guiyin Zhang, Xiuhong Huang, Lichen Lin, Changren Zhou, Yanpeng Jiao and Hong Li. Blood compatibility evaluations of two-dimensional Ti3C2Tx nanosheets. Biomedical Materials, 2022,17(2): )025004

16.      Wu S , Cheng X , Xu X , et al. In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing[J]. Journal of Materials Chemistry B, 2022, 10.598-606

17.      Tianxing Zhou, Shuangcong Xie, Chunze Zhou, Yiyu Chen, Hong Li, Ping Liu, Rongjian Jiang, Lifeng Hang,* and Guihua Jiang. All-In-One Second Near-Infrared Light-Responsive Drug Delivery System for Synergistic Chemo-Photothermal Therapy. ACS Appl. Bio Mater. 2022, 5, 3841−3849

18.      Manman Sun, Ke Huang, Xueshi Luo, Hong Li*. Templated Three-Dimensional Engineered Bone Matrix as a Model for Breast Cancer Osteolytic Bone Metastasis Process. International Journal of Nanomedicine. 2021;16: 8391-8403.

19.      Xueshi Luo, Shuyun Zhang, Binghong Luo, Hong Li*. Engineering collagen fiber templates with oriented nanoarchitecture and concerns on osteoblast behaviors. International Journal of Biological Macromolecules. 185,2021, 77-86,

20.      Yanyi Li; Haobin Huang; Chongwei Ding; Xiaoping Zhou; Hong Li. β-Cyclodextrin-based Metal-Organic Framework as a Carrier for Zero-order Drug Delivery. Materials Letters. 2021:129766.

21.      Zhiqiang Huang, Zhenzhao Guo, Manman Sun, Shaomao Fang, Hong Li* .Reduced Graphene Oxide-coated Electrospun Fibre: Effect of Orientation, Coverage and Electrical Stimulation on Schwann Cells Behavior. Journal of Materials Chemistry B. 2021:9: 2656-65

22.      Ping He, Yanyi Li, Zhiqiang Huang, Zhen-Zhao Guo, Binghong Luo, Chang-Ren Zhou, Hong Li*. A multifunctional coaxial fiber membrane loaded with dual drugs for guided tissue regeneration. Journal of Biomaterials Applications. 2020;34:1041-51.

23.      Zhenzhao Guo, Jiao Genlong, Zhiqiang Huang, Hong Li*, Yao Ge, Zhe Wu, Pei Yu and Zhizhong Li. Synergetic effect of growth factor and topography on fibroblast proliferation. Biomedical Physics & Engineering Express, 18 Nov 2020, 6(6) 065036

生物矿化与组织修复，2023年6月，中国，北京，科学出版社 

1.国家自然科学基金（面上），组织工程三维多级有序微纳结构骨微环境作为乳腺癌骨转移体外模型的研究（31971284,2020.1-2013.23,57万元，主持）

2.国家自然科学基金（面上），成骨细胞在仿Osteoid结构上生物矿化及其调控机制研究，（31571008，2016/01-2019/12，64万，主持）

3.国家自然科学基金（面上）：基于分子识别的原位仿生矿化再生修复牙硬组织的模拟研究（2009～2011，30870612,33万元，主持)

4.国家自然科学基金（面上）: 有序化纳米胶原纤维复合骨性靶向分子的体内外生物矿化机理研究（2011～ 2013，33万元，31070852, 主持）

5.广东省科技计划项目：分层接触引导纳米牙周组织再生膜研制及应用研究（2014.9-2016.12， 10万元，2013B010403015，主持）

6.科研创新和培育重点项目：壳聚糖参与骨组织修复的机制及其壳聚糖基骨修复材料的分子设计与制备（2011～ 2013，30万，主持）

一种β-磷酸三钙/海藻酸复合微球及其制备和应用，201410400341.8

  本科：材料科学基础，无机非金属材料学

  研究生：材料结构与性能，生物矿化，化学前沿概论，化学研究方法

中国生物医学工程学会生物材料分会委员副主任委员，中国生物材料学会产学研委员会委员，中国生物材料学会生物陶瓷分会委员。

广东省材料教学指导委员会副主任委员