个人信息 |
姓名: 徐石海 部门: 化学与材料学院 性别: 男 职务: 主任 职称: 教授 学位: 博士 毕业院校: 中山大学 联系电话: 13070263778 电子邮箱: txush@jnu.edu.cn 办公地址: 广州市,暨南大学分析测试中心203房 通讯地址: 广州市,暨南大学分析测试中心203房 邮编: 510632 传真: 荣誉奖励: 国家级青年人才 |
联系方式固定电话:02085227796 移动电话:13070263778 微信号:xu13070263778 QQ:879887173 |
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个人简介湖南隆回人,教授,博士,博士生导师。 研究简介 一直从事海洋生物活性成分研究,先后主持国家十五“863”课题“海藻中抗肿瘤和治疗心血管疾病活性化合物的分离与鉴定(No. 2001AA628100,2004AA628030)”和十一五“863”课题 “珊瑚中抗肿瘤活性化合物的分离与结构鉴定(No. 2006AA09Z408))”、国家自然科学基金课题“抗肿瘤海洋生物碱的研究(No. 20002001)”、“Ircinia属海绵中抗肿瘤活化合物的发现与优化(No. 20772048)”、南海海绵共附微生物中活性先导化合物发现(No.2117094)、珊瑚中抗污损活性物质研究(No. 4136155)、海藻中抗污损活性物质研究(No.21672084)、海绵中抗海洋污损生物的代谢研究(No. 41876154)及以HER2靶点的海绵中新型抗乳腺癌活性成分及作用机制研究(No.42376085)和广东省自然科学基金课题、广东省科技计划课题、广东省自然资源厅课题和广州市科技计划课题等三十余项课题,通过这些项目的完成,从海洋生物品种海藻、珊瑚、海绵中分离鉴定从我国南海各种海洋生物品种中分离鉴定1500多种海洋天然产物,其中400余种为首次发现的新化合物,这些化合物的分属于萜类、生物碱、甾醇、神经酰胺、脂肪酸,糖类。对具有自主知识产权的且生物活性较强的4个海洋生物碱、一个二糖酯与一个环肽化合物进行全合成,并进行结构修饰得到100多个修饰化合物。在国内外权威学术期刊,如:Organic Letters,British Journal of Pharmacology,Journal of Natural Products,Steroids,Marine Drugs等期刊上发表学术论文200余篇,申请国内专利20项,授权15项。 学习经历1993/09-1996/07, 中山大学,化学系,博士 1990/09-1993/07, 湘潭大学,化学系,硕士 1985/09-1988/06,湖南邵阳学院,化学系,大学 工作经历研究工作经历 2002/10-现在,暨南大学化学与材料学院,化学系,教授,博士生导师 2008/03-2008/09,美国密西西比大学,药学院生药系做高级访问学者 1998/10-2002/10, 暨南大学生命科学与技术学院,化学系,副教授; 1996/07-1998/10, 暨南大学理工学院,化学系,讲师 研究方向1、海洋药物化学的分离:从海藻、珊瑚、海绵等海洋生物及共附生微生物中分离海洋药物活性先导化合物; 2、海洋药物全合成:对具有自主知识产权的活性化合物进行全合成、结构修饰及规模化制备; 3、药物活性筛选、成药性评价及应用:活性化合物进行于化妆品、药物及材料等开发。 主要论文1、Liang, YongQian; Liao, XiaoJian; Zhao, BingXin* and Xu, Shihai*,Novel 3,4-seco-3,19- dinorspongian and 5,17-epoxy-19-norspongian diterpenes from the marine spongeSpongiasp., Organic Chemistry Frontiers, 2020, 7,3253–3261. 2、Lin, Xiao; Zhou,Yongjun; Liu,Liyun; Zhu, Hongrui;Chen,Yeping;Wang,Shuping; Sun,Fan; Chai, Ling; Liu, Buming; Xu, Shihai* and Hou-Wen Lin*, Compound Discovery and Structure-Activity Relationship Study of Neoantimycins Against Drug-Resistant Cancer Cells, Frontiers in Chemistry, 2019,7(481),1-10. 3、Jiao, FuRong; Gu, BinBin; Zhu, HongRui; Zhang,Yun; Liu,Ke Chun; Zhang,Wei;Han, Hua *; Xu, Shihai* and Hou-Wen Lin*, Asperfloketals A and B, the First Two Ergostanes with Rearranged A and D Rings: From the Sponge-Associated Aspergillus flocculosus 16D-1, The Journal of Organic Chemistry,2020,doi.org/10.1021/acs.joc.0c02049 4、Chen, Shengtian; Wang, Junfeng; Lin, Xiuping; Zhao, Bingxin; Wei, Xiaoyi; Li, Guangqiang; Kaliaperumal, Kumaravel; Liao, Shengrong; Yang, Bin; Zhou, Xuefeng; Liu, Juan; Xu, Shihai*; Liu, Yonghong*, Chrysamides A-C, Three Dimeric Nitrophenyl trans-Epoxyamides Produced by the Deep-Sea-Derived Fungus Penicillium chrysogenum SCSIO41001, Organic Letters, 2016, 18(15): 3650-3653. 5、Xu, WenJie; Liao, XiaoJian; Xu, ShiHai*; Diao, JianZhong; Du, Bin; Zhou, XuLong; Pan, Shan-Shan,Isolation, Structure Determination, and Synthesis of Galaxamide, A Rare Cytotoxic Cyclic Pentapeptide from a Marine Algae Galaxaura filamentosa,Organic Letters, 2008, 10(20): 4569-4572. 6、Xiong, Sheng; Pang, Hui-dan,Fan, Jun,Ge, Feng,Yang, Xiaoxia,Liu, Qiuying,Liao, Xiaojian,Xu, Shihai*,In vitro and in vivo antineoplastic activity of a novel bromopyrrole and its potential mechanism of action,British Journal of Pharmacology,2010, 159(4): 909-918. 7、Ding, LiJian; Yuan, Wei; Liao, XiaoJian; Han, BingNan; Wang, ShuPing; Li, ZhiYong; Xu, ShiHai*; Zhang, Wei*; Lin, HouWen*, Oryzamides A-E, Cyclodepsipeptides from the Sponge-Derived Fungus Nigrospora oryzae PF18, Journal of Natural Products,2016, 79(8): 2045-2052. 8、Li, DaiChun; Yang,Yan; Zhang, Bing; Liao, Xiao Jian; Jiang, ZhiHui; Xu, ShiHai*and Zhao, BingXin*, Three New Butenolides from the Green Alga Caulerpa racemosavar. Turbinata,Chem. Biodiversity , 2020, 17, e2000022,1-6 9、Liu,TingTing; Liao, XiaoJian; Xu, ShiHai*and Zhao, BingXin*, Solieritide A, a new polyketide from the red alga Solieriasp.,Natural Product Research,2020,3,1-7 10、Guana, ZhuoBin; Liang, Yong Qian; Lin, JiaLi; Liao, XiaoJian; Xu, ShiHai*and Zhao, BingXin*, Two new pyrrolidine alkaloids from the red alga Acanthophora spicifera,Natural Product Research,2020,3,1-7 11、Pang, Xiaoyan;Lin, Xiuping; Zhou, Xuefeng;Yang, Bin; Tian, Xinpeng;Wang, Junfeng*;Xu, ShiHai*; Yonghong Li*, New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSIO06786,Fitoterapia,2020,104406,(140),1-5 12、Liang, Yong Qian; Liao, Xiao Jian; Lin, Jia Li; Xu, Wei; Chen, Guo Dong*; Zhao, Bing Xin*; Xu, Shi Hai*,Spongiains A-C: Three new spongian diterpenes with ring A rearrangement from the marine sponge Spongiasp.,Tetrahedron, 2019, 75(27): 3802-3808. 13、Pang, Xiaoyan; Cai, Guodi; Lin, Xiuping; Salendra, Limbadri; Zhou, Xuefeng; Yang, Bin; Wang, Junjian; Wang, Junfeng*; Xu, Shihai*; Liu, Yonghong*,New Alkaloids and Polyketides from the Marine Sponge-Derived Fungus Penicillium sp. SCSIO41015 ,Marine Drugs,2019, 17(7): 0-398. 14、Ding, Lijian; Ren, Lu; Li, Shuang; Song, Jingjing; Han, Zhiwen; He, Shan*; Xu, Shihai*, Production of New Antibacterial 4-Hydroxy-alpha-Pyrones by a Marine Fungus Aspergillus niger Cultivated in Solid Medium,Marine Drugs,2019, 17(6): 1-8. 15、Zhang, Jun*; Ling, Wei; Yang, Zhiqiang; Liang, Yan; Zhang, Linyan; Guo, Can; Wang, Kailing; Zhong, Balian; Xu,Shihai*; Xu, Ying*, Isolation and Structure-Activity Relationship of Subergorgic Acid and Synthesis of Its Derivatives as Antifouling Agent,Marine Drugs, 2019, 17(2): 1-11. 16、Lai, Wei; Qin, Sheng Ying; Zou, Ge; Liao, Xiao Jian; Chen, Guo Dong; Zhang, Hua; Zhao, Bing Xin*;Xu, Shi Hai*,Sinulaspirolactam A, a novel aza-spirocyclic valerenane sesquiterpenoid from soft coral Sinularia sp.,Journal of Asian Natural Products Research, 2019, 21(5): 494-501. 17、Sun, Yueguang; Li, Hang bin; Zhou, Rong; Wang, Hailin; Feng, Pengju*; Xu, Shihai*,Total Synthsis of Thermoactionamide andIts Analogue,Heterocycles, 2019, 98(6): 789-797. 18、Lunagariya, Jignesh; Bhadja, Poonam; Zhong, Shenghui; Vekariya, Rohit; Xu, Shihai*,Marine Natural Product Bis-indole Alkaloid Caulerpin: Chemistry and Biology,Mini Reviews in Medicinal Chemistry, 2019, 19(9): 751-761. 19、Ding, Lijian*; Xu, Peng; Li, Te; Liao, Xiaojian; He, Shan*; Xu, Shihai*,Asperfurandiones A and B, two antifungal furandione analogs from a marine-derived fungus Aspergillus versicolor,Natural Product Research,2019, 33(23): 3404-3408. 20、Li, Jing; Wang, Zhuo; Yang, Fan; Jiao, WeiHua; Lin, HouWen*; Xu, ShiHai*,Two new steroids with cytotoxicity from the marine sponge Dactylospongia elegans collected from the South China Sea,Natural Product Research, 2019, 33(9): 1340-1344. 21、Liang, YongQian; Liao, XiaoJian; Zhao, BingXin*; Xu, ShiHai*,(+ )- and (-)-Spongiterpene, a pair of new valerenane sesquiterpene enantiomers from the marine sponge Spongia Sp.,Natural Product Research, 2019, 16(9): 1-5. 22、Zhang, Hua; Lai,Wei; Guan, ZhuoBin; Liao, XiaoJian; Zhao, BingXin*& Xu, ShiHai*, A new thiodiketopiperzaine from the marine sponge Tedania sp. ,Natural Product Research,2019.2.1-6 23、Lin,JiaLi; Liang, YongQian; Liao, XiaoJian;Yang,JianTing; Li, Dai-Chun; Huang,YuLing; Jiang, ZhiHui; Xu, ShiHai*& Zhao, BingXin*, Acanthophoraine A, a new pyrrolidine alkaloid from the red algaAcanthophora spicifera,Natural Product Research,2019,4,1-7, 24、Zhou, Rong; Liao, XiaoJian;Li,Hangbin; Li,Jing; Feng,Pengju*; Zhao,Binxin*; Xu, ShiHai*,Isolation and Synthesis of Misszrtine A: A Novel Indole Alkaloid From Marine Sponge-Associated Aspergillus sp. SCSIO XWS03F03,Frontiers in Chemistry, 2018, 6(6): 1-7. 25、Zhang, Jun*;Yang, Zhiqiang; Liang, Yan; Zhong, Liping; Lin, Huiting; Zhong, Balian; Li, Liangchun*; Xu,Shihai*; Liu,Yonghong*,Four New C9 Metabolites from the Sponge-Associated Fungus Gliomastix sp ZSDS1-F7-2,Marine Drugs, 2018, 16(7): 0-231. 26、Zhou, Rong;Sun,Yueguang; Li,Hangbin; Long, Weili; Liao, XiaoJian;Feng,Pengju*; Xu, ShiHai*,Synthesis and Biological Evaluation of Reniochalistatins A–E and a Reniochalistatin E Analogue,ChemMedChem, 2018, 13(9): 2202-2207. 27、Li, Jing; Yang, Fan;Wang, ZhuoWei ; Wang,ShuPing; Zhao,BinXin; Jiao, WeiHua*;Xu, ShiHai*and Lin,HouWen*, Unusual antiinflammatory meroter- penoids from the marine sponge Dactyl ospongia sp.,Org. Biomol. Chem., 2018, 16, 6773 - 6782. 28、Hangbin Li,Xiaojian Liao,Yueguang Sun,Rong Zhou,Weili Long,Le Li,Liuqun Gu*and Shihai Xu*,An Economical Synthesis of Caulerpin and Evaluation of Its New Anticancer Activities,ChemistrySelect ,2018, 3, 12406– 12409. 29、Li, Jing; Yang, Fan;Liu, Li; Jiao, WeiHua*;Xu, ShiHai*and Lin, HouWen*,Popolohuanones G-I, Dimeric Sesquiterpene Quinones with IL-6 Inhibitory Activity from the Marine Sponge Dactylospongia elegans,Chem. Biodiversity , 2018, 15, e1800078,1-7 30、Wang, Ying; Lin, Xiu Ping; Ju, Zhi Ran; Liao, Xiao Jian; Huang, Xiao Jun; Zhang, Chen; Zhao, Bing Xin*; Xu, Shi Hai*, Aspergchromones A and B, two new polyketides from the marine sponge-associated fungus Aspergillus sp SCSIO XWS03F03,Journal of Asian Natural Products Research, 2017, 19(7): 684-690. 31、Bai, Defa; Yu, Siming; Zhong, Shenghui; Zhao, Bingxin; Qiu, Shaoling; Chen, Jianwei; Lunagariya, Jignesh; Liao, Xiaojian*; Xu, Shihai*,D-Amino Acid Position Influences the Anticancer Activity of Galaxamide Analogs: An Apoptotic Mechanism Study,International Journal of Molecular Sciences, 2017, 18(3): 0-544. 32、Chen, Shengtian; Wang, Junfeng; Wang, Zhen; Lin, Xiuping; Zhao,Bingxin; Kaliaperumal, Kumaravel; Liao, Xiaojian; Tu,Zhengchao; Li, Jianlin; Xu, Shihai*; Liu, Yonghong*,Structurally diverse secondary metabolites from a deep-sea-derived fungus Penicillium chrysogenum SCSIO 41001 and their biological evaluation,Fitoterapia, 2017, 117: 71-78. 34、Zhang, Jun*; Ip, Fanny C. F.; Liang, Yan; Ip, Nancy Y.; Zhong, BaLian; Lai, ChunWang; Xu, Shihai*,A new iridoid glycoside and a new cinnamoyl glycoside from Scrophularia ningpoensis Hemsl,Natural Product Research, 2017, 31(20): 2361-2368. 35、Zou,Ge; Liao, Xiaojian; Peng,Qi; Chen, GuoDong; Wei,FangYing; Xu, ZhengXiong; Zhao, Bing Xin*and Xu, Shi Hai*, A new α-pyrone from the deep-sea actinomycete Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111(T),Journal of Asian Natural Products Research, 2017, 15(11),1232-1238. 36、 Ju, Zhiran; Qin, Xiaochu; Lin, Xiuping; Wang, Junfeng; Kumaravel Kaliyaperumal; Tian, Yongqi; Liu, Juan ; Liu, Fen; Tu, Zhengchao; Xu, Shi Hai*; Liu, Yonghong*,New phenyl derivatives from endophytic fungus Botryosphaeria sp. SCSIO KcF6 derived of mangrove plant Kandelia candel,Natural Product Research, 2016, 30(2): 192-198. 37、Sun, Huan; Liu, Fen; Feng, Mei-Ran; Peng, Qi; Liao, Xiao-Jian; Liu, Ting-Ting; Zhang, Jun*; Xu, Shi Hai*,Isolation of a new cytotoxic polyhydroxysterol from the South China Sea soft coral Sinularia sp.,Natural Product Research, 2016, 30(24): 2819-2824. 38、Ding, Lijian; Yuan, Wei; Peng, Qi; Sun, Huan;Xu, Shi Hai*,Secondary Metabolites Isolated from the Sponge-Associated Fungus Nigrospora oryzae,Chemistry of Natural Compounds, 2016, 52(5): 969-970. 39、Ding, Lijian; Yuan, Wei; Li, Yingxin; Liao, Xiaojian; Sun, Huan; Peng, Qi; Han, Bingnan; Lin, Houwen; Li, Zhiyong*; Yang, Fan*; Xu, Shi Hai*,Hypocrol A, a new tyrosol derivative from a sponge-derived strain of the fungus Hypocrea koningii,Natural Product Research,2016, 30(14): 1633-1638. 40、Lunagariya, Jignesh; Zhong, Shenghui; Chen, Jianwei; Bai, Defa; Bhadja, Poonam; Long, Weili; Liao, Xiaojian*; Tang, Xiaoli*; Xu, Shi Hai*,Design and Synthesis of Analogues of Marine Natural Product Galaxamide, an N-methylated Cyclic Pentapeptide, as Potential Anti-Tumor Agent in Vitro,Marine Drugs, 2016, 14(9): 0-161. 41、Peng, Qi; Liu, Fen; Sun, Huan; Liao, XiaoJian; Feng, MeiRan; Liu, TingTing; Xu, ZhengXiong; Zhang, Jun*;Xu, Shi Hai*,A new sesquiterpene from the gorgonian coral Menella sp.,Natural Product Research, 2016, 30(20): 2299-2304. 42、徐石海通讯,(+)- and (−)-Spongiterpene, a pair of new valerenane sesquiterpene enantiomers from the marine sponge Spongia sp.,Natural Product Research,2021年7月 43、徐石海通讯A New Dinorspongian Diterpene with Pyridyl D-Ring from the Marine Sponge Spongia sp.,Chinese Journal of Organic Chemistry, 2022, 42, 901~904. 44、徐石海通讯Two new pyrrolidine alkaloids from the red alga Acanthophora spicifera, Natural Product Research,2021年12月 45、徐石海通讯Solieritide A, a new polyketide from the red alga Solieria sp.,Natural Product Research,2023年1月 46、徐石海通讯Asperflomide and asperflosamide, new N-methylated cyclopeptides from the marine sponge-derived fungus Aspergillus flocculosus 16D-1,Tetrahedron,109 (2022) 132579 47、徐石海通讯Structurally various sorbicillinoids from the deep-sea sediment derived fungus Penicillium sp. SCSIO06871,Bioorganic Chemistry 107 (2021) 104600。 48、徐石海通讯New Tetramic Acid Derivatives From the Deep-Sea-Derived Fungus Penicillium sp. SCSIO06868 With SARS-CoV-2 Mpro Inhibitory Activity Evaluation,Frontiers in Microbiology,2021年9月 49、徐石海通讯Mixed-Linker Isoreticular Zn(II) Metal−Organic Frameworks as Brønsted Acid−Base Bifunctional Catalysts for Knoevenagel Condensation Reactions,Inorganic Chemistry,2022, 61, 8339−8348 50、Two New 2,5-Dioxopiperazines from the Marine Sponge Haliclona baeri,Chin徐石海通讯ese Journal of Organic Chemistry, 2022, 42, 1839~1842 51、徐石海通讯Two new halogenated metabolites from the red alga Laurencia sp.,JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2023, VOL. 25, NO. 1, 61–67 52、徐石海通讯A new chlorobenzoate derivative from the red alga Solieria sp.,Journal of Asian Natural Products Research,2023年1月 53、徐石海通讯Clionaterpene, a New Cadinene Sesquiterpene from the Marine Sponge Cliona sp. J. Mar. Sci. Eng. 2023, 11, 131 54、徐石海通讯Spongimides A and B, two new alkaloids from the marine sponge Spongia sp.,JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2023年4月 55、徐石海通讯Antitumor activity of galaxamide involved in cell apoptosis and stemness by inhibiting Wnt/β‐catenin pathway in cervical cancer,DRUG DEVELOPMENT RESEARCH,2023;1–13. 56、徐石海通讯Synthesis of marine cyclopeptide galaxamide analogues as potential anticancer agents,Marine Drugs,2022, 20, 158. 57、徐石海通讯Two new pairs of enantiomeric butenolides from the marine sponge Suberties sp.,Chemistry & Biodiversity,2023年7月 58、徐石海通讯Applying molecular networking for targeted isolation of depsipeptides,RSC Adv., 2021, 11, 2774–2782. 主要著作承担课题主持国家级科研项目: 1、国家自然基金面上项目,42376085,以HER2靶点的海绵中新型抗乳腺癌活性成分及作用机制研究,2024/01-2027/12,52万元,在研,主持 2、国家自然基金面上项目,21672084,海藻中抗污损活性物质研究,2017/01-2020/12,65万元,结题,主持 3、国家自然基金面上项目,41876145,海绵中抗海洋污损生物的代谢产物研究,2019/01-2022/12,62万元,结题,主持 4、国家自然基金面上项目,41376155,珊瑚中抗污损活性物质研究,2014/01-2017/12,82万元,结题,主持 5、国家自然基金面上项目,21172094,南海海绵共附微生物中活性先导化合物发现,2012/01-2015/12,65万元,结题,主持 6、国家自然基金面上项目,20772048,Ircinia属海绵中抗肿瘤活性化合物的发现与优化,2008/01-2010/12,28万元,结题,主持 7、国家自然基金面上项目,20002001,抗肿瘤海洋生物碱研究,2001/01-2003/12,16万元,结题,主持 8、国家“十四五”重点研发项目,2018YFC0310900,深海动植物药物先导化合物高效挖掘与候选药物成药性研究,总经费2367万元,子课题:抗胶质瘤候选药物环五肽GL712的系统成药性评价,2018YFC0310902, 2018,09-2021,09,经费150万元/2367万元,结题,主持; 9、国家“十三五”海洋“863”重点研发项目,海洋生物功能天然产物的发掘、优化与合成,远海大型生物全新天然产物的发现与药物先导化合物优化;54万元/1001万元,结题,主持 10、科技部863计划,2001AA628100,海藻中抗肿瘤和治疗心血管疾病活性化合物的分离与鉴定,35万元,2002/01-2004/12,结题,主持 11、科技部863计划,20060109Z408,珊瑚中抗肿瘤活性化合物的分离与结构鉴定,80万元,2006/12-2009/11,结题,主持 百万级省部级科研项目: 1、广东省自然资源厅、海绵及微生物中抗肿瘤活性化合物发现、规模化制备与成药性评价关键技术,粤自然资合[2024]28号,200万,2024-2025,在研,主持。 2、广东省自然资源厅、海藻来源抗肿瘤环肽 GLD 规模化制备、作用机制及成药性研究,粤自然资合[2020]037号,200万,2020-2022,结题,主持。 3广东省自然资源厅、合成生物学技术构效优化海洋微生物抗肿瘤先导物,粤自然资合[2021]048号,100万/600万,2021-2023,结题,子课题主持。 4、广州市科技计划项目,海藻中抗肿瘤活性成分分离、合成及药效学的关键技术,No.201704030042 ,100万,结题,主持 横向科研项目: 1、红色素CAU的合成,2022年03月至2024年3月,15万元,完成 发明专利1、徐石海; 钟生辉; 白德发; 陈建维,一种环五肽合成方法,2016-10-02, 中国, ZL 2016 100239897.2. 2、龙伟立,李杭斌,徐石海*,赵冰心,一种简易高效合成蕨藻红素的方法,2019-09-17,中国, ZL 201810063548.9. 3、李杭斌,龙伟立,徐石海*,一种简单合成蕨藻红素的方法,2019-09-17,中国, ZL 201810386674.8. 4、周荣,徐石海*,一种活性环八肽Reniochalistatin E及其类似物的合成方法,2019-05-08, 中国,ZL201711057116.9. 5、周荣,徐石海*,冯鹏举,廖小建,赵冰心,一种活性生物碱Misszrtlide的合成方法,2019-09-17,中国,ZL 201810057929.6. 6、孙月光,李杭斌,徐石海*,一种抗菌活性环六肽Thermoactinoamide A 的合成方法,2020-09-04,中国,ZL201810157377.6. 7、周荣,孙月光,徐石海*,廖小建,一类广泛活性环七肽Reniochalistatin A-D的合成方法,2020-12-15,中国,ZL 201810157160.5. 8、徐石海,蕨藻红素的规模化制备工艺,,2022年11月,ZL202111196765.3 讲授课程本科:《有机化学》,《有机化学实验》 硕士研究生:《天然产物化学》,《有机波谱学》 博士研究生:《化学方法导论》一个章节 荣誉奖励 国家级青年人才
社会职务1、中国家药学会海洋药物专业委员会理事 2、中国生物化学与分子生物学会海洋生物化学与分子生物学分会理事 3、广东省化学化工学会有机化学专业委员会理事 4、广东省高等学校实验教学指导委员会副主任委员 5、广东省实验室安全委员会专家组组长 6、《实验室研究与探索》、《实验技术与管理》编委 7、国家自然基金通讯评审专家 8、广东省、福建省、江西省、河北省、江苏省等科技项目评审专家 9、暨南大学分析测试中心主任 10、广东海洋协会副会长 |