暨南大学化学与材料学院教授，博导。研究领域包括过渡金属催化，光催化，生物活性分子的合成及生物偶联。已经累计在Angew. Chem. Int. Ed.、 J. Am. Chem. Soc.、 Org. Letts.、Chem. Comm.等知名学术期刊上发表了五十多篇SCI论文。在3本英文书籍中贡献专项章节。主持过多个基金项目包括国家自然科学基金面上项目，香港研资局优配研究基金项目，广东省基础与应用基础研究基金项目，深圳市知识创新计划基础研究项目等。

2004，博士学位, 香港大学，(导师: 支志明院士)。

1996，硕士学位, 华东理工大学，(导师: 荣国斌教授)。

1993，学士学位, 华东理工大学。

2018/11-现在，暨南大学, 教授。

2012/08-2018/10，香港大学, 研究助理教授。

2012/02-2012/07，香港大学, 研究主任。

2009-2012, 香港大学, 博士后 (合作导师: 支志明院士)

2007-2009, Texas A&M University, 博士后 (合作导师: Daniel Romo教授)。

2004-2007，香港大学, 助理研究员。

过渡金属催化，不对称催化和合成，天然产物和药物分子合成， 生物偶联和生物探针合成。

1） J. Bai, S. Yan, Z. Zhang, Z. Guo,* C.-Y. Zhou,* “Visible Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions”Org. Lett., 2021, 23, 4843-4848.

2） B. Lin, X. Zhang, C.-Y. Zhou*,C.-M. Che*, “A PEGylated N-heterocyclic carbene-gold(I) complex: an efficient catalyst for cyclization reaction in water”, Org. Chem. Front., 2021, 8, 1216-1222.

3） S. Yan, J. Rao, C.-Y. Zhou*,“Chemoselective Rearrangement Reactions of Sulfur Ylide Derived from Diazoquinones and Allyl/Propargyl Sulfides”Org. Lett., 2020, 22, 9091-9096.

4） K. Wu, L.-L. Wu, C.-Y. Zhou*, C.-M. Che*, “Transition‐Metal‐Free C(sp2)–C(sp2) Cross‐Coupling of Diazo Quinones with Catechol Boronic Esters”Angew. Chem., Int. Ed. 2020,59, 16202-16208.

5）K. Wu, C.-Y. Zhou*, C.-M. Che*, “Perfluoroalkyl Aziridines with Ruthenium Porphyrin Carbene Intermediates”, Org. Lett.2019, 21, 85.

6）K. Wu, B. Cao, C.-Y. Zhou*, C.-M. Che*,“Rh^II-Catalyzed Intermolecular C-H Arylation of Aromatics with Diazo Quinones”, Chem.-Eur. J.2018, 24, 4815.

7）H. Wang, C.-Y. Zhou*, C.-M. Che*, “Cobalt-Porphyrin-Catalyzed Intramolecular Buchner Reaction and Arene Cyclopropanation of In Situ Generated Alkyl Diazomethanes”, Adv. Synth. Catal.2017, 359, 2253.

8）A. R. Reddy, F. Hao, K. Wu, C.-Y. Zhou*, C.-M. Che*, “Cobalt Porphyrin Catalyzed Intrmolecular Cyclopropanation of N-Alkyl Indoles/Pyrroles with Alkylcarbene: Efficient Synthesis of Polycyclic N-Heterocycles”，Angew. Chem., Int. Ed. 2016, 55, 1810.

9）A. R. Reddy^†,C.-Y. Zhou^†, Z. Guo, J. Wei, C.-M. Che*, “Ruthenium Porphyrin Catalyzed Diastereoselective Intramolecular Alkylcarbene Insertion to C-H Bonds of Alkyldiazomethanes Generated In Situ from N-Tosylhydrazones”, Angew. Chem., Int. Ed. 2014, 53, 14175–14180（†共同第一作者）

10）A. R. Reddy,C.-Y. Zhou*,C.-M. Che*, “Ruthenium Porphyrin Catalyzed Three-Component Reaction of Diazo Compounds, Nitrosoarenes, and Alkynes: An Efficient Approach to Multifunctionalized Aziridines”, Org. Lett. 2014, 16, 1048.

11）W. Xiao, J. Wei, C.-Y. Zhou*, C.-M. Che*,“[Ru^IV(F₂₀-TPP)Cl₂] efficiently catalysed inter- and intra-molecular nitrene insertion into sp³ C–H bonds of hydrocarbons using phosphoryl azides as nitrene sources”Chem. Commun.2013, 49, 4619.

12）C.-Y. Zhou, J.-C. Wang, J. Wei, Z.-J. Xu, Z. Guo, K.-H. Low, C.-M. Che*, “Dirhodium Carboxylates Catalysed Enantioselective Coupling Reactions of α-Diazophosphonates, Anilines andElectron Deficient Aldehydes”, Angew. Chem., Int. Ed. 2012, 51, 11376.

13）A. R. Reddy, Z. Guo, F.-M. Siu, C.-N. Lok, F. Liu, K.-C. Yeung, C.-Y. Zhou*, C.-M. Che*, “Diastereoselective Ruthenium Porphyrin-Catalyzed Tandem Nitrone Formation/1,3-Dipolar Cycloaddition for Isoxazolidines. Synthesis, in Silico Docking Study and in VitroBiological Activities”，Org. Biomol. Chem.2012, 10, 9165.

14）C.-Y. Zhou, J. Li, S. Peddibhotla, D. Romo*, “Mild Arming and Derivatization of Natural Products via an In(OTf)₃-Catalyzed Arene Iodination”,Org. Lett.2010, 12, 2104.

15）C.-Y. Zhou, J.-S. Huang, C.-M. Che*, “Ruthenium Porphyrin-Catalyzed Carbenoid Transfer Reactions”, Synlett2010, 2681. (review)

16）C.-Y. Zhou, C.-M. Che*,“Highly Efficient Au(I)-Catalyzed Intramolecular Addition of β-Ketoamide to Unactivated Alkenes”, J. Am. Chem. Soc.2007, 129, 5828.

17）C.-Y. Zhou,P. W. H. Chan, C.-M. Che*,“Gold(III) Porphyrin-Catalyzed Cycloisomerization of Allenones”, Org. Lett.2006, 8, 325.

18）Y.-D. Du, C.-Y. Zhou, W.-P. To, H.-X. Wang, C.-M. Che*, “Iron porphyrin catalysed light driven C–H bond amination and alkene aziridination with organic azides”,Chem. Sci., 2020, 11, 4680.

19）H.-X. Wang, Q. Wan, K.-H. Low, C.-Y. Zhou, J.-S. Huang, J.-L. Zhang, C.-M. Che*, “Stable group 8 metal porphyrin mono- and bis(dialkylcarbene) complexes: synthesis, characterization, and catalytic activity”Chem. Sci.2020, 11, 2243.

20）H.-X. Wang, R. Yann, Q. Wan, C.-Y. Zhou, C.-M. Che*, “Iridium(III)-Catalyzed Intermolecular C(sp3)-H Insertion Reaction of Quinoid Carbene: A Radical Mechanism”, Angew. Chem. Int. Ed.2020, 59, 1845.

21）H.-X. Wang, Q. Wan, K. Wu, K.-H. Low, C. Yang, C.-Y. Zhou, J.-S. Huang,* C.-M. Che*, “Ruthenium(II) Porphyrin Quinoid Carbene Complexes: Synthesis, Crystal Structure, and Reactivity toward Carbene Transfer and Hydrogen Atom Transfer Reactions”, J. Am. Chem. Soc.2019, 141, 9027.

22）J. Li, J. S. Cisar, C.-Y. Zhou, B. Vera, H. Williams, A. D. Rodrı́guez, B. F. Cravatt, D. Romo*, “Simultaneous structure–activity studies and arming of natural products by C–H amination reveal cellular targets of eupalmerin acetate”, Nature Chemistry2013, 5, 510.

23）W. Xiao, C.-Y. Zhou, C.-M. Che* “Ruthenium(IV) porphyrin catalyzed phosphoramidation of aldehyde with phosphoryl azide as nitrene source” Chem. Comm.,2012, 48, 5871.

24）M.-Z. Wang, C.-Y. Zhou, C.-M. Che*,“A silver-promoted auto-tandem catalysis for the synthesis of multiply substituted tetrahydrocarbazoles”Chem. Comm.,2011, 47, 1312.

25）P. Liu, C.-Y. Zhou, S. Xiang, C.-M. Che*, “Highly efficient oxidative carbon–carbon coupling with SBA-15-support iron terpyridine catalyst”,Chem. Comm.,2010, 46, 2739.

26）C.-M. Ho, J.-L. Zhang, C.-Y. Zhou, O.-Y. Chan, J. J. Yan, F.-Y. Zhang, J.-S. Huang, C.-M. Che*, “A Water-Soluble Ruthenium Glycosylated Porphyrin Catalyst for Carbenoid Transfer Reactions in Aqueous Media with Applications in Bioconjugation Reactions”,J. Am. Chem. Soc.,2010, 132, 1886.

27）V. K.-Y. Lo, C.-Y. Zhou, M.-K. Wong, C.-M. Che*, “Silver(I)-mediated highly enantioselective synthesis of axially chiral allenes under thermal and microwave-assisted conditions”,Chem. Comm.,2010, 46, 213.

[1] C.-M. Che, V. K.-Y. Lo, C.-Y. Zhou, “Oxidation by Metals (Nitrene)”, Comprehensive Organic Synthesis II, 2014, V7, 26-85, Elsevier Ltd.

[2] C.-Y. Zhou,V. K.-Y. Lo, C.-M. Che, “Metalloporphyrin-Catalyzed C-C Bond Formation”, Handbook of Porphyrin Science, World Scientific: Singapore, 2012, 21, 321-376.

[3] C.-M. Che, C.-Y. Zhou, E. L.-M. Wong, “Catalysis by Fe=X Complexes (X = NR, CR2)”, Topics in Organometallic Chemistry,2011, 33, 111-138. Publisher: Springer GmbH.

1） 国家自然科学基金面上项目 “金属卡宾参与的多组分反应和串联反应”(21472159)，主持人。

2）General Research Fund （香港研资局优配研究基金）“Transition metal catalyzed carbene transformations of non-stabilized diazoalkanes generated in situ from hydrazones”(17306714)，主持人。

3）广东省基础与应用基础研究基金项目“金属醌卡宾介导的叶立德转换反应”（2021A1515012023），主持人。

4）深圳市知识创新计划基础研究项目“过渡金属催化重氮化合物串联反应构建多取代杂环化合物”（JCYJ20150629151046879），主持人。

5）国家973项目 “金属配合物激发态的基础与应用研究”(2013CB834800)，科研骨干。

6）国家自然科学基金面上项目“过渡金属卟啉络合物催化的卡宾及氮宾碳氢键插入反应及其应用研究”（21272197），科研骨干。

有机化学，化学与材料概论，有机化学实验，生产实习