With over two decades of dedicated respiratory clinical practice, Dr. Chen specializes in:

· Early diagnosis & comprehensive management of common respiratory disorders (chronic obstructive pulmonary disease [COPD], asthma, lung cancer, pulmonary infections)

· Critical care expertise in acute respiratory failure and other life-threatening respiratory emergencies

Interventional Pulmonology Proficiencies
• Bronchoscopic airway stent implantation
• Balloon dilation for tracheobronchial stenosis
• Endobronchial ultrasound (EBUS) & EBUS-guided transbronchial needle aspiration (EBUS-TBNA)
• Bronchoscopic cryoablation/thermal ablation techniques
• Bronchoscopic photodynamic therapy (PDT)
• Medical thoracoscopy

Advanced Respiratory Support Skills
▸ Invasive/non-invasive mechanical ventilation
▸ Multidisciplinary critical care management
▸ Complex airway intervention planning

From October 2002 to present, Dr. Chen has been working in the First Affiliated Hospital of Jinan University.

1. Long Xie¹, ^# , Xiao-Ya Zhu², ^# , Li Xu^{3, 4, #} , Xiao-Xie Xu^{3, 4} , Ze-Fan Ruan^{3, 4} , Ming-Xiang ,Huang ^5, ⃰, Li Chen^{6, 7, ⃰}, Xi-Wen Jiang^{3, 4, ⃰}. Accurate and Affordable Detection of Rifampicin and Isoniazid Resistance in Tuberculosis Sputum Specimens by Multiplex PCR-Multiple Probes Melting Analysis. Infection. 2024 Dec;52(6):2371-2398. doi: 10.1007/s15010-024-02295-w. (IF=5.4)

2. Cao X, Liang Y, Feng H, Chen L*, Liu S*.Construction and evaluation of a risk prediction model for pulmonary infection-associated acute kidney injury in intensive care units. Clin Transl Sci. 2023 Jul 24. doi: 10.1111/cts.13599.(IF=3.98)

3. Jun He ¹, Yue Zhao ¹, Zhenli Fu ¹, Li Chen ¹, Kongzhen Hu , Xiaoyan Lin , Ning Wang , Weijian Huang , Qi Xu , Shuhua He , Ying He , Linliang Song , Mei Xia Fang , Jie Zheng , Biying Chen , Qiuyan Cai , Jiangnan Fu , Jin Su. A novel tree shrew model of lipopolysaccharide-induced acute respiratory distress syndrome. Journal of Advanced Research. 2024 Feb:56:157-165. doi:10.1016/j.jare.2023.03.009. Epub 2023 Apr 8. (IF=11.4)

4. Xinyi Cao, Honglin Feng, Shengming Liu & Li Chen*. Analysis of clinical characteristics and prognosis of 68 patients with primary pulmonary choriocarcinoma. BMC Pulmonary Medicine (2023) 2023 Mar 8;23(1):75. doi: 10.1186/s12890-023-02368-w.(IF=3.2)

5. 蔡秋燕，王静，曾桂星，罗玉玲，刘升明，陈丽*. 重组人血管内皮抑制素联合NPE方案治疗晚期非小细胞肺癌疗效的Meta分析，海南医学，2021，32（4）526-532.

6. Li Chen*; Liqiong Yu; Yi Wu; Wai-kit Ming; Zhihong Huang; Shengming Liu, A 52-Year-Old Man With an 11-Month History of Fever, Cough, Chest Pain, Pleural Effusion, and Left Lung Atelectasis，Chest. 2020 Oct;158(4):e153-e157. doi: 10.1016/j.chest.2020.05.546. (IF=9.5)

7. 陈丽*, 刘华勇, 骆文志, 陈嘉伟, 吴义, 黄志宏, 刘升明.SO2衍生物通过NLRP3炎症小体促进气道上皮细胞炎症发生,中国病理生理杂志, 2019,35 (4): 718-724. 

8. 冯一, 陈丽, 李红, 王素梅, 黄志宏, 吴义, 刘升明. FIZZ1在吸烟大鼠COPD模型肺组织的表达及与气道炎症的相关性研究,中国病理生理杂志, 2018, 34 (6): 1101-1108.

9. Chen Li, Huang zhihong, et al., The NLRP3 Inflammasome Regulates Bronchial Epithelial Cell Injury and Pro-apoptosis After Exposure to Biomass Fuel Smoke. Am J Respir Cell Mol Biol. 2016; 55(6):815-824.（IF=5.9）