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姓名: 白卫滨

部门: 理工学院

直属机构: 理工学院

性别:

职务: 理工学院副院长,兼食品科学与工程系主任,食品安全与营养研究院常务副院长

职称: 教授

学位: 博士

毕业院校: 中国农业大学

联系电话: 02085226635

电子邮箱: baiweibin@163.com

办公地址: 暨南大学第二理工楼465

通讯地址: 广州天河区黄埔大道西601号

邮编: 510632

传真: 02085226635

荣誉奖励: 国家级青年人才,省级青年人才

联系方式

个人简介

白卫滨,博士,教授,博士生导师。任暨南大学理工学院副院长,兼食品科学与工程系主任、食品安全与营养研究院常务副院长,广东省食品安全分子快速检测工程技术中心主任,广东省食品学会青年工作委员会主任,中国食品科学技术学会第三届青年工作委员会委员,食品领域TOP期 刊 Critical Reviews in Food Science and Nutrition 和Food and Chemical Toxicology杂志客座主编。入选教育部新世纪优秀人才支持计划,广东省高校优秀青年教师培养计划。任暨南大学食品安全与营养方向学科带头人,主要研究方向为富含花色苷果蔬的产品开发及功能研究、食物中有害物风险评估及营养干预、食品分子快速检测溯源技术等。近年来主持了国家自然科学基金 5 项,国家重点研发计划课题任务1 项,“十二五”国家科技支撑计划课题 1 项,广东省重点研发计划1项,广州市民生科技重大专项1项,到账经费累计1600多万元。以第一作者或者通讯作者发表学术论文 70余篇,其中已第一或者通讯作者发表在食品领域top 期刊《Critical Reviews in Food Science and Nutrition 》、《Journal of Agricultural and Food Chemistry》、《Food Chemistry》等SCI Top期刊论文50余篇。申请发明专利10项,授权 5项,并转让2项。起草地方标准2项(第一和第二起草人)。参编著作 4 部(其中副主编 1 部)。


学习经历

1998.92002.6,山东农业大学食品科学与工程专业,本科

2004.92006.6,暨南大学微生物与生化药学专业,硕士

2006.92009.12,中国农业大学食品科学专业,博士


工作经历

2002.9-2010.3,山东农业工程学院,讲师

2010.3至今,暨南大学理工学院食品科学与工程系,教授/博导

2012.11月至今,暨南大学理工学院副院长/食品安全与营养研究院常务副院长/食品科学与工程系主任/科技处副处长


研究方向

(1)食品天然功能色苷等对慢性疾病营养干预:采用蓝莓、草莓等果蔬中花色苷,国际上率先开展了对生殖损伤的营养干预,建立了对生殖功能评价的体系和细胞及动物模型评价平台;同时对皮肤光老化、脂质代谢、血糖和肝损伤等营养干预也开展了系列研究;利用平台体系筛选药食同源功能活性因子,配伍并研发男性和女性备孕产品、护肤产品、减肥及护肝产品等。
(2)研究花色苷标准样品制备、产品开发及色泽控制:(a)快速、高效的果蔬花色苷单体等生物活性物质的提取、分离、鉴定与纯化技术体系;(b)富含花色苷产品的果酒和果醋功能产品的开发;(c)富含花色苷产品加工和贮藏过程中色泽的变化及护色技术研究。
(3)研究花色苷稳态化体系:针对花色苷抗氧化能力强,但稳定性差、吸收率低等缺点,采用壳聚糖、环糊精等构建稳态化的纳米/微米包埋体系,并研究精准靶向释放,开发花色苷功能配料。
(4)研究食品分子溯源,核酸适配体快检技术、解毒营养干预:针对食品特别是高附加值食品掺假乱像,建立了食品种属鉴定和地理标识检测技术。开展了核酸适配体对重金属、毒素、微生物、激素等的筛选及快检技术和快检试剂盒产品的研究开发。利用核酸适配体技术开展污染物的体内解毒研究。


主要论文

代表性论文:

[1] Cai DB, Li XS, Chen JL, Jiang XW, Ma XQ, Sun JX, Tian LM, Vidyarthi SK, Xu JW, Pan ZL, Bai WB*. A comprehensive review on innovative and advanced stabilization approaches of anthocyanin by modifying structure and controlling environmental factors. Food Chemistry, 2021, DOI10.1016/j.foodchem.2021.130611. (IF=7.5141Top)

[2] Jiang XW, Li X, Feng WJ, Qin YG, Li Zhen, Nie H, Qin WB, Han L*, Bai WB*. Baking of methionine-choline deficient diet aggravates testis injury in mice. Food and Chemical Toxicology, 2021, DOI10.1016/j.fct.2021.112245. (IF=6.023, 1Top)

[3] Luo ZY, Duan HY, Yang YC, Zhang WT, Ramaswamy HS, Bai WB*, Wang C. High pressure assisted extraction for cadmium decontamination of long rice grain. Food Control, 2021, DOI10.1016/j.foodcont.2021.107987. (IF=5.548, 1)

[4] Chen JL, Xu BJ, Sun JX, Jiang XW, Bai WB*. Anthocyanin supplement as a dietary strategy in cancer prevention and management: A comprehensive review. Critical Reviews in Food Science and Nutrition, 2021, DOI10.1080/10408398.2021.1913092.(IF=11.176, 1Top)

[5] Li XS, Li HW, Cai DB, Li P, Jin JT, Jiang XW, Li ZH, Tian LM, Chen GB,

Sun JX, Bai WB*. Chronic oral exposure to cadmium causes liver inflammation by NLRP3 inflammasome activation in pubertal mice. Food and Chemical Toxicology, 2020, DOI10.1016/j.fct.2020.111944. (IF=6.023, 2Top)

[6] Li XS, Zhang L, Peng ZY, Zhao YQ, Wu, KY, Zhou N, Yan Y, Ramaswamy, HS, Sun JX, Bai WB*. The impact of ultrasonic treatment on blueberry wine anthocyanin color and its In-vitro anti-oxidant capacity. Food Chemistry, 2020, DOI10.1016/j.foodchem.2020.127455. (IF=7.5141Top)

[7] Sun JX, Chen JL, Mei ZX, Luo ZY Ding LJ, Jiang XW, Bai WB*.

Synthesis, structural characterization, and evaluation of cyanidin-3-O-glucoside-loaded chitosan nanoparticles. Food Chemistry, 2020, DOI10.1016/j.foodchem.2020.127239. (IF=7.5141Top)

[8] Ran GJ, Wu FM, Ni XY, Li XY, Li XS, Liu DL, Sun JX, Xie CF, Yao DS,

Bai WB*. A novel label-free electrochemical aptasensor with one-step assembly process for rapid detection of lead (II) ions. Sensors and Actuators B-Chemical, 2020, DOI10.1016/j.snb.2020.128326. (IF=7.46, 1Top)

[9] Li XS, Yao ZL, Yang DC, Jiang XW, Sun JX, Tian LM, Hu J, Wu BY,

Bai WB*. Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage. Journal of Hazardous Materials, 2019, DOI10.1016/j.jhazmat.2019.121706. (IF=10.588,1Top)

[10] Sun JX, Li XH, Luo HX, Ding LJ, Jiang XW, Li XS, Jiao R, Bai WB*. Comparative Study on the Stability and Antioxidant Activity of Six Pyranoanthocyanins Based on Malvidin-3-glucoside. Journal of Agricultural and Food Chemistry, 2020,68(9):2783-2794, DOI10.1021/acs.jafc.9b06734.

(IF=5.279,1Top)

[11] Li XS, Yao ZL, Jiang XW, Sun JX, Ran GJ, Yang X, Zhao YQ, Yan y, Chen ZS, Tian LM, Bai WB*. Bioactive compounds from Cudrania tricuspidata: A natural anticancer source. Critical Reviews in Food Science and Nutrition, 2020 DOI10.1080/10408398.2018.1541866. (IF=11.1761Top)


[12] Chen ZS, Yang DC, Jiang XW, Tian LM, Sun JX, Tian DB, Bai WB*.

Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice. Food and Chemical Toxicology, 2019, DOI10.1016/j.fct.2019.04.05. (IF=6.0232Top)

[13] Li XS, Guo JT, Jiang XW, Sun, JX, Tian LM, Jiao R, Tang YG, Bai WB*. Cyanidin-3-O-glucoside protects against cadmium-induced dysfunction of sex hormone secretion via the regulation of hypothalamus-pituitary-gonadal axis in male pubertal mice. Food and Chemical Toxicology, 2019, DOI:10.1016/j.fct.2019.04.033 (IF=6.0232Top)

[14] Li X, Lu JL, Sun JX*, Jiang XW, Li XS, Li Y, Jiao R, Tian LM, Bai WB*.

Cyanidin-3-O-glucoside promotes progesterone secretion by improving cells viability and mitochondrial function in cadmium-sulfate-damaged R2C cells. Food and Chemical Toxicology, 2019, DOI10.1016/j.fct.2019.03.040. (IF=6.0232Top).

[15] Li Y, Ran GJ, Lu G, Ni XY, Liu DL, Sun JX, Xie CF, Yao DS*, Bai WB*. Highly Sensitive Label-Free Electrochemical Aptasensor Based on Screen-Printed Electrode for Detection of Cadmium (II) Ions. Journal of the Electrochemical Society, 2019, 166(6): B449-B455 (IF=4.136, 2Top)

[16] Jiang XW, Cao CT, Sun WW, Chen ZS, Li XS, Nahar, L, Sarker, SD, Georgiev, MI, Bai WB*. Scandenolone from Cudrania tricuspidata fruit extract suppresses the viability of breast cancer cells (MCF-7) in vitro and in vivo. Food and Chemical Toxicology, 2019, 126: 56-66 (IF=6.0232Top)

[17] Sun JX, Luo HX, Li XH, Li XS, Lu YY, Bai WB*. Effects of low power ultrasonic treatment on the transformation of cyanidin-3-O-glucoside to methylpyranocyanidin-3-O-glucoside and its stability evaluation. Food Chemistry, 2019, 276: 240-246 (IF=4.9462Top)

[18] Tian LM, Tan YS, Chen GW, Wang G, Sun JX, Ou SY, Chen W, Bai WB*. Metabolism of anthocyanins and consequent effects on the gut microbiota. Critical Reviews in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1533517 (IF=11.1761)

[19] Li XS, Yao ZL, Jiang XW, Sun JX, Ran GJ, Yang X, Zhao YQ, Yan Y, Chen ZS, Tian LM, Bai WB*. Bioactive compounds from Cudrania tricuspidata: A natural anticancer source. Critical Reviews in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1541866 (IF=11.1761)

[20] Jiang XW, Zhu CJ, Li XS, Sun JX, Tian LM, Bai WB*. Cyanidin-3-O-glucoside at Low Doses Protected against 3-Chloro-1,2-propanediol Induced Testis Injury and Improved Spermatogenesis in Male Rats. Journal of Agricultural and Food Chemistry, 2018, 66(48): 12675-12684 (IF=5.279, 1)

[21] Jiang XW, Li XS, Zhu CJ, Sun JX, Tian LM, Chen W, Bai WB*. The target cells of anthocyanins in metabolic syndrome. Critical Review in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1491022 (IF=11.176, 1)

[22] Yang DC, Jiang XW, Sun JX, Li X, Li XS, Jiao R, Peng ZY, Li YQ, Bai WB*. Toxic effects of zearalenone on gametogenesis and embryonic development: A molecular point of review. Food and Chemical Toxicology, 2018, 119: 24-30 (IF=6.0232Top)

[23] Liu ZH, Hu YF, Li X, Mei ZX, Wu S, He Y, Jiang, XW, Sun JX, Xiao, JB, Deng, LH*, Bai WB*. Nanoencapsulation of Cyanidin-3- O-glucoside Enhances Protection Against UVB-Induced Epidermal Damage through Regulation of p53-Mediated Apoptosis in Mice. Journal of agricultural and food chemistry, 2018, 66(21): 5359-5367(IF=5.279, 1)

[24] Jiang H, Lai NS, Tang J*,Tian X, Wei FF, Bai WB*, Xu YL. Effect of photo-oxidation on the emissive properties of truxene. Journal of Phottchemistry and Photobiology A-Chemistry, 2018, DOI10.1016/j.jphotochem.2018.09.028.

(IF=4.291, 3)

[25] Peng ZY, Jiang XW, Sun JX, Li XS, Hu YF, Tian LM, Bai WB*. Recent Progress in Protective Effect of Flavonoids against Skin Photodamage. Food Science, 2019,40(11):246-253.

[26] Ran GJ, Jiang XW, Li HY, Chen JL, Li XS, Sun JX, Bai WB*. Rapid Preparation of Cyanidin-3-glucoside from Mulberry Fruit by Preparative Medium Pressure Liquid Chromatography. Food Science, 2019, 40(3):94-100.

[27] Sun JX, Li MW, Zou FY, Bai S, Jiang XW, Tian LM, Ou SY, Jiao R*, Bai WB*. Protection of cyanidin-3-O-glucoside against acrylamide- and glycidamide-induced reproductive toxicity in leydig cells. Food and Chemical Toxicology, 2018, 119: 268-274 (IF=6.0232Top)

[28] Li X, Guo JT, Liang N, Jiang XW, Song Y, Ou SY, Hu YF, Jiao R*, Bai WB*. 6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells. Frontiers in Pharmacology, 2018, 9, DOI: 10.3389/fphar.2018.00159 (IF=5.812)

[29] Li XS, Jiang XW, Sun JX, Zhu CJ, Bai WB*. Recent advances of medical foods in China: The opportunities and challenges under standardization. Food and chemical toxicology, Food and Chemical Toxicology, 2018, 119: 342-354 (IF=6.0232Top)

[30] Wen LN, Jiang XW, Sun JX, Li X, Li XS, Tian LM, Li Y, Bai WB*. Cyanidin-3-O-glucoside promotes the biosynthesis of progesterone through the protection of mitochondrial function in Pb-exposed rat leydig cells. Food and Chemical Toxicology, 2018, 112: 427-434 (IF=6.0232Top)

[31] Li X, Jiang XW, Sun JX, Zhu CJ, Li XL, Tian LM, Liu L, Bai WB*. Cytoprotective effects of dietary flavonoids against cadmium-induced toxicity: Mechanisms of dietary flavonoids against cadmium. Annals of the New York Academy of Sciences, 2017 , 1398 (1) :5-19 (IF=5.691 2)

[32] Hu YF, Li ZH, Wang LF, Deng LH, Sun JXJiang XW, Zhang Y, Wang YFBai WB*. Scandenolone, a natural isoflavone derivative from Cudrania tricuspidata fruit, targets EGFR to induce apoptosis and block autophagy flux in human melanoma cells. Journal of Functional Foods, 2017 , 37 : 229-240. (IF=4.4511区,Top)

[33] He Y, Hu YF, Jiang XW, Chen TF, Ma YT, Wu S, Sun JX, Jiao R, Li X, Deng LH*Bai WB*. Cyanidin-3-O-glucoside inhibits the UVB-induced ROS/COX-2 pathway in HaCaT cells. Journal of Photochemistry and Photobiology. B, Biology, 2017, 177: 24-31.(IF=6.2522)

[34] Sun JX, Xu W, Zhu CJ, Hu YF, Jiang XW, Su ZJ, Huang YD, Jiao R *, Bai WB*. Cyanidin-3-O-Glucoside Protects against 1,3-Dichloro-2-Propanol-Induced Reduction of Progesterone by Up-regulation of Steroidogenic Enzymes and cAMP Level in Leydig Cells. Frontiers in Pharmacology. 2016, 7; doi: 10.3389/fphar.2016.00399 (IF=5.812)

[35] Hu YF,Ma YT,Wu S,Chen TF,He Y,Sun JX,Jiang XW,Huang YD,Deng LH *, Bai WB*. Protective effect of cyanidin-3-O-glucoside against ultraviolet B radiation-induced cell damage in human HaCaT keratinocytes. Frontiers in Pharmacology.2016; doi: 10.3389/fphar.2016.00301 (IF=5.812)

[36] Li MW, Sun JX, Zou FY, Bai S, Jiang XW, Jiao Rui, Ou SY, Zhang H, Su ZJ, Huang YD, Bai WB*. Glycidamide inhibits progesterone production through reactive oxygen species-induced apoptosis in R2C Rat Leydig Cells. Food and Chemical Toxicology. 2016 (IF=6.023, 2Top)

[37] Sun JX, Mei ZX, Tang YJ, Ding LJ, Jiang GC, Zhang C, Sun AD*, Bai WB*. Stability, antioxidant capacity and degradation kinetics of pelargonidin-3-glucoside exposed to power ultrasound at low temperature. Molecules, 2016, 21(9), 1109; doi:10.3390/molecules21091109 (IF=4.4112)

[38] Sun JX, Li XH, Lin XY, Mei ZX, Li YT, Ding LJ*, Bai WB*. Sonodegradation of Cyanidin-3-glucosylrutinoside: degradation kinetic analysis and its impact on antioxidant capacity in vitro. Journal of the Science of Food and Agriculture, 2016 (IF=5.2792区Top)

[39] Zhang ZH, Zou YY, Wu TG, Huang CH, Pei KH, Zhang GW, Lin XH, Bai WB*, Ou SY*. Chlorogenic acid increased 5-hydroxymethylfurfural formation when heating fructose alone or with aspartic acid at two pH levels. Food Chemistry, 2016, 190: 832–835(IF=7.5141top)

[40] Song Y, Wen LN, Sun JX, Bai WB*, Jiao R, Hu YF, Peng XC, He Yong, Ou SY*. Cytoprotective mechanism of ferulic acid against high glucose-induced oxidative stress in cardiomyocytes and hepatocytes. Food & Nutriton Research, 2016, 60, 30323. (IF=3.8942)

[41] Sun JX, Bai S, Bai WB*, Zou FY, Zhang L, Li GQ, Hu YF, Li MW, Yan RA, Su ZJ*, Huang YD. 1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells. Food Chemistry, 2014, 154:330–336 (IF=7.5141top)

[42] Sun JX, Bai S, Bai WB*, Zou FY, Zhang L, Su ZJ, Zhang QH, Ou SY, Huang YD *, Toxic Mechanisms of 3-Monochloropropane-1,2-Diol on Progesterone Production in R2C Rat Leydig Cells. Journal of Agricultural and Food Chemistry, 2013, 61: 9955-9960 (IF=5.279, 1top)

[43Bai WB, Xu WT, Huang KL, Yuan YF, Cao SS, Luo YB. A novel common primer multiplex PCR (CP-M-PCR) method for the simultaneous detection of meat species. Food Control, 2009, 20: 366-370 (IF=5.5482)


主要著作

[1] 车会莲、马良、白卫滨、邵美丽、李昌模等,食品安全性评价综合实验:中国林业出版社,2014(参编)

[2] 贾敬敦,蒋丹平,陈昆松,葛毅强,白卫滨等,食品产业科技创新发展战略,化学工业出版社,95.6万字,2013 (参编)

[3] 贾敬敦,孙晓明,陈昆松,葛毅强,白卫滨等, 农业前沿技术与战略新兴产业, 中国农业出版社, 120万字,2011 (参编)

[4] 张燕,张辉,孙建霞,白卫滨等,果品的商品化处理与配送,中国劳动社会保障出版社,12.5万字,2012 (副主编)

[5] 转基因食品安全与检测技术. 北京:科学出版社,2009,参编


承担课题

主持课题:

[1] 广东省重点领域研发计划项目:食品中常见污染物健康危害评估技术,2019-2022,650万;

[2] 国家自然科学基金(面上):超声催陈促进红葡萄酒花色苷衍生物的生成机制,2018-202160万;

[3] 国家重点研发计划:主要食品全产业链品质质量控制关键技术开发研究课题任务、2016-2020,经费107万元;

[4] 广州市产学研协同创新重大专项:岭南特色富含花色苷的果酒、果醋超声催陈关键技术及产品功能评价研究、2017-2020,经费100万元;

[5] 国家自然科学基金(面上):草莓天竺葵素-3-葡萄糖苷对食品中氯丙醇导致细胞氧化应激的营养干预机制,2015-2018,经费82万元;

[6] 国家科技支撑计划课题:食品中热反应伴生危害物毒理学检测及风险评估关键技术研究,2012-2014,经费145万元;

[7] 国家自然科学基金(青年): 杨梅花色苷抑制重金属损伤睾丸间质细胞的机制研究, 2012-201527万元;

[8] 国家863计划项目:优良益生菌高效筛选与应用关键技术子课题,2011-201550万元;



发明专利

[1]一种利用多重PCR技术检测转基因番木瓜的方法.国家发明专利,2017,第一完成人(授权并转让)
[2]矢车菊素-3-O-葡萄糖苷1,3-二氯-2-丙醇的生殖毒性的干预作用.国家发明专利,2019,第一完成人(授权)
[3]矢车菊素-3-葡萄糖苷对UVB诱导HaCaT细胞损伤的防护作用.国家发明专利,2018,第一完成人(授权)
[4]一种稳定包埋花色苷的改性环糊精/羧甲基壳聚糖纳米颗粒的制备方法.国家发明专利,2020,第一完成人(授权)
[5]异黄酮类化合物Final-2在制备肺癌细胞葡萄糖转运蛋白表达抑制剂中的应用.国家发明专利,2020,第一完成人(授权)
[6]一种利用中压液相色谱从桑葚中制备矢车菊素-3-葡萄糖苷的方法.国家发明专利,2020,第一完成人(授权)
[7]镉离子核酸适配体及丝网印刷电极电化学生物传感器.国家发明专利,2019,第一完成人(授权并转让)


讲授课程

  • 食品营养学(本科生)

  • 转基因食品安全性评价(本科生)

  • 现代食品营养学(研究生)

  • 应用现代食品营养学(研究生)

  • 食品质量与安全研究进展(研究生)

荣誉奖励

国家级青年人才,省级青年人才

社会职务

担任广东省食品安全分子快速检测工程技术中心主任、广东省食品学会青年工作委员会主任、中国食品科学技术学会第三届青年工作委员会委员,目前担任食品领域Top期刊Critical Reviews in Food Science and Nutrition和Food and Chemical Toxicology杂志的客座主编等。