郑先创，男，暨南大学纳米光子学研究院教授，博导，纳米光子学研究院副院长。2010年于南京大学材料与工程系获理学学士学位，2015年于南京大学高分子科学与工程系获理学博士学位。2015-2019年于斯坦福大学医学院从事博士后研究工作，2020年加入暨南大学纳米光子学研究院。研究方向为智能光学探针及其生物医学成像应用。代表性研究论文发表于 Nat. Biomed. Eng.、Nat. Commun.、Adv. Mater.、Angew. Chem. Int. Ed.、Cancer Res.、Nano Lett. 等知名期刊，论文他引两千余次。参与出版英文专著两部。获2016年度江苏省优秀博士论文、2019年度中国生物医学工程学会黄家驷生物医学工程奖一等奖（第6完成人）、2021年度中国生物材料学会科学技术奖二等奖（第2完成人）、2021年度江苏省科学技术奖一等奖（第2完成人）。现主持国家自然科学基金面上项目、广东省珠江人才计划青年拔尖人才等科研项目。

2010 - 2015 年， 南京大学化学化工学院高分子科学与工程系  博士

2006 - 2010 年， 南京大学材料科学与工程系材料物理专业   学士

2020 年 至今，  暨南大学纳米光子学研究院     教授

2015 - 2019年， 斯坦福大学医学院分子影像中心   博士后

1） 智能磷光成像探针

2） 活体内光操控研究

3） 智能光声成像探针

4） 疗效监测与药物评估

代表性论文：

[17] Wangning Zhang; Chenming Chan; Kaiyu Zhang; Haifeng Qin; Bo-Yang Yu; Zhaoli Xue*; Xianchuang Zheng*; Jiangwei Tian*; Discovering a new drug against acute kidney injury by using a tailored photoacoustic imaging probe, Advanced Materials, 2024, 36(18): 2311397

[16] Tiange Zhang; Xiaoshuai Liu*; Haifeng Qin; Yufeng Lin; Baojun Li; Xiqun Jiang; Xianchuang Zheng*; Semiphysical design concept for developing miniaturized microrobots in vivo, Nano Letters, 2024, 24(16): 4834-4842

[15] Wenze Zhang; Zhuoxia Shen; Chaoran Li; Yumeng Yang; Tiange Zhang; Bo-Yang Yu; Xianchuang Zheng*; Jiangwei Tian*; A “defend–attack and capture flag” strategy for cascade management of hepatic ischemia reperfusion injury, Chemical Engineering Journal, 2024, 487: 150501

[14] Haifeng Qin; Xiaoshuai Liu*; Tiange Zhang; Yufeng Lin; Huaying Wu; Fei Xiao; Baojun Li*; Xianchuang Zheng*; Optically reconfigurable platelet architecture in vivo, ACS Photonics, 2024, DOI: 10.1021/acsphotonics.4c00123

[13] Kaiyu Zhang; Lei Sun; Wangning Zhang; Mingyuan Cao; Xiaonan Ma; Bo-Yang Yu; Haijun Xu*; Xianchuang Zheng*; Jiangwei Tian*; Discovery of natural products alleviating renal fibrosis with a viscosity-responsive molecular probe, Analytical Chemistry, 2024, 96(16): 6356-6365

[12] Xiaoshuai Liu; Shuai Wu; Huaying Wu; Tiange Zhang; Haifeng Qin; Yufeng Lin; Baojun Li; Xiqun Jiang; Xianchuang Zheng*; Fully active delivery of nanodrugs in vivo via remote optical manipulation, Small Methods, 2024, 8(1): 2301112

[11] Xiaoshuai Liu*; Huaying Wu; Shuai Wu; Haifeng Qin; Tiange Zhang; Yufeng Lin; Xianchuang Zheng*; Baojun Li*; Optically programmable living microrouter in vivo, Advanced Science, 2023, 10(32): 2304103（内封面论文）

[10] Tiange Zhang; Shuai Wu; Haifeng Qin; Huaying Wu; Xiaoshuai Liu*; Baojun Li; Xianchuang Zheng*; An optically controlled virtual microsensor for biomarker detection in vivo, Advanced Materials, 2022, 34(47): 2270326（内封面论文）

[9] Xiaoshuai Liu; Qing Gao; Shuai Wu; Haifeng Qin; Tiange Zhang; Xianchuang Zheng*; Baojun Li*; Optically manipulated neutrophils as native microcrafts in vivo, ACS Central Science, 2022, 8(7): 1017（封面论文）

[8] Cheng Liu#; Xianchuang Zheng#; Tingting Dai; Huiliang Wang; Xian Chen; Bing Chen; Tianying Sun; Feng Wang; Steven Chu; Jianghong Rao*; Reversibly photoswitching upconversion nanoparticles for super-sensitive photoacoustic molecular imaging, Angewandte Chemie International Edition, 2022, 61(19): e202116802（VIP论文）

[7] Wangning Zhang; Fangjian Cai; Haijun Xu*; Yan Wu; Xie-An Yu; Lei Sun; Tiange Zhang; Bo-Yang Yu; Xianchuang Zheng*; Jiangwei Tian*; Small-molecule photoacoustic imaging probe with aggregation-enhanced amplitude for real-time visualization of acute kidney injury, Analytical Chemistry, 2022, 94(27): 9697-9705

[6] Wangning Zhang; Zhuoxia Shen; Yan Wu; Wenze Zhang; Tiange Zhang; Bo-Yang Yu; Xianchuang Zheng*; Jiangwei Tian*; Renal-clearable and biodegradable black phosphorus quantum dots for photoacoustic imaging of kidney dysfunction, Analytica Chimica Acta, 2022, 1204: 339737

[5] Cheng Li#; Xianchuang Zheng#; Weizhi Chen#; Shilu Ji; Yang Yuan; Xiqun Jiang*; Tumor microenvironment-regulated and reported nanoparticles for overcoming the self-confinement of multiple photodynamic therapy, Nano Letters, 2020, 20(9): 6526-6534

[4] Xianchuang Zheng; Liyang Cui; Min Chen; Luis A. Soto; Edward E. Graves; Jianghong Rao*; A near-infrared phosphorescent nanoprobe enables quantitative, longitudinal imaging of tumor hypoxia dynamics during radiotherapy, Cancer Research, 2019, 79(18): 4787-4797

[3] Xianchuang Zheng; Hui Mao; Da Huo; Wei Wu; Baorui Liu; Xiqun Jiang*; Successively activatable ultrasensitive probe for imaging tumour acidity and hypoxia, Nature Biomedical Engineering, 2017, 1: 0057

[2] Xianchuang Zheng; Huang Tang; Chen Xie; Jialiang Zhang; Wei Wu; Xiqun Jiang*; Tracking cancer metastasis in vivo by using an iridium-based hypoxia-activated optical oxygen nanosensor, Angewandte Chemie International Edition, 2015, 54(28): 8094-8099（内封面论文）

[1] Xianchuang Zheng; Xin Wang; Hui Mao; Wei Wu; Baorui Liu; Xiqun Jiang*; Hypoxia-specific ultrasensitive detection of tumours and cancer cells in vivo, Nature Communications, 2015, 6: 5834（ESI高引论文）

[1]《Molecular Imaging》 (Second Edition), Principles and Practice, Chapter 27 - The Chemistry in Surface Functionalization of Nanoparticles for Molecular Imaging.

Xianchuang Zheng; Joanna Wang; Jianghong Rao; Elsevier Inc, 2021

https://www.sciencedirect.com/science/article/abs/pii/B9780128163863000211

[2]《Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences》, Chapter 12 - Tracking of Hypoxia and Cancer Metastasis with Iridium(iii)-based O2 Probes.

Xianchuang Zheng; Xiqun Jiang; Royal Society of Chemistry, 2018

https://books.rsc.org/books/edited-volume/753/chapter-abstract/471119/Tracking-of-Hypoxia-and-Cancer-Metastasis-with?redirectedFrom=fulltext

[1] 国家自然科学基金委员会, 面上项目, 52373287, 基于光学捕获及上转换荧光的光控纳米医疗机器人

研究, 2024-01-01 至 2027-12-31, 51万元, 在研, 主持

[2] 国家自然科学基金委员会, 面上项目, 22175078, 可逆式乏氧响应的光激活光声成像探针研究, 2022-

01-01 至 2025-12-31, 60万元, 在研, 主持

[3] 广东省科学技术厅, 珠江人才计划青年拔尖人才, 2021QN02Y666, 活体内光操纵的智能光学成像探针,

2022-12 至 2025-11, 50万元, 在研, 主持

[4] 广州市科学技术局, 市校（院）联合资助项目, 202201020029, 成像引导的光操纵血栓清除基础研究,

2022-04 至 2024-03, 20万元, 结题, 主持

《光学成像技术》

《论文写作与学术规范》

《高等光电子技术实验》

中国生物物理学会             会员

中国光学会员                会员

World Molecular Imaging Society   会员