主要论文(近十年以通讯作者发表的主要论文):
1.Zhuang J, Liu S, Du GF, Fang Z, Wu J, Li N, Zhong T, Xu J, He QY, Sun X. YjgM is a crotonyltransferase critical for polymyxin resistance of Escherichia coli. Cell Rep. 2024, 43(5), 114161.doi: 10.1016/j.celrep.2024.114161.
2.Zhong T, Wu H, Hu J, Liu Y, Zheng Y, Li N, Sun Z, Yin XF, He QY, Sun X. Two synonymous single-nucleotide polymorphisms promoting fluoroquinolone resistance of Escherichia coli in the environment. J Hazard Mater.2024, 469,133849. doi: 10.1016/j.jhazmat.2024.133849.
3.Fang Z, Zhao X, Zhang Z, Wu J, Cheng J, Lei D, Li N, Ge R, He QY, Sun X. Unveiling a novel mechanism for competitive advantage of ciprofloxacin-resistant bacteria in the environment through bacterial membrane vesicles. J Hazard Mater. 2024, 466, 133453. doi: 10.1016/j.jhazmat.2024.133453.
4.Fang Z, Lai F, Cao K, Zhang Z, Cao L, Liu S, Duan Y, Yin X, Ge R, He QY, Sun X. Potential Role of Lysine Acetylation in Antibiotic Resistance of Escherichia coli. mSystems. 2022, 7(6), e0064922. doi: 10.1128/msystems.00649-22.
5.Cao K, Zhang T, Li N, Yang XY, Ding J, He QY, Sun X. Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae. mSystems. 2022, 7(3), e0022122. doi: 10.1128/msystems.00221-22.
6.Zheng YD, Pan Y, He K, Li N, Yang D, Du GF, Ge R, He QY, Sun X. SPD_1495 Contributes to Capsular Polysaccharide Synthesis and Virulence in Streptococcus pneumoniae. mSystems. 2020, 5(1), e00025-20. doi: 10.1128/mSystems.00025-20.
7.Fang ZY, Zhang ZY, Zheng YD, Lei D, Zhuang J, Li N, He QY, Sun X. Repurposing cinacalcet suppresses multidrug-resistant Staphylococcus aureus by disruption of cell membrane and inhibits biofilm by targeting IcaR. J Antimicrob Chemother. 2024, 79(4), 903-917. doi: 10.1093/jac/dkae051.
8.Lei D, Cao L, Zhong T, He QY, Sun X. Residue Lys219 of CpxR is critical in the regulation of the antibiotic resistance of Escherichia coli. J Antimicrob Chemother. 2023, 78(8), 1859-1870. doi: 10.1093/jac/dkad171.
9.Cao K, Li N, Wang H, Cao X, He J, Zhang B, He QY, Zhang G, Sun X. Two zinc-binding domains in the transporter AdcA from Streptococcus pyogenes facilitate high-affinity binding and fast transport of zinc. J Biol Chem. 2018, 293(16), 6075-6089. doi: 10.1074/jbc.M117.818997.
10.Zheng YD, Zhong T, Wu H, Li N, Fang Z, Cao L, Yin XF, He QY, Ge R, Sun X. Crizotinib Shows Antibacterial Activity against Gram-Positive Bacteria by Reducing ATP Production and Targeting the CTP Synthase PyrG. Microbiol Spectr. 2022, 10(3), e0088422. doi: 10.1128/spectrum.00884-22.
11.Liu J, Wei Q, Wang Z, Sun X, He QY. Proteomic Study of the Adaptive Mechanism of Ciprofloxacin-Resistant Staphylococcus aureus to the Host Environment. J Proteome Res. 2022, 21(6), 1537-1547. doi: 10.1021/acs.jproteome.2c00140.
12.Dong Y, Miao X, Zheng YD, Liu J, He QY, Ge R, Sun X. Ciprofloxacin-Resistant Staphylococcus aureus Displays Enhanced Resistance and Virulence in Iron-Restricted Conditions. J Proteome Res. 2021, 20(5), 2839-2850. doi: 10.1021/acs.jproteome.1c00077.
13.Du GF, Yin XF, Yang DH, He QY, Sun X. Proteomic Investigation of the Antibacterial Mechanism of trans-Cinnamaldehyde against Escherichia coli. J Proteome Res. 2021, 20(5), 2319-2328. doi: 10.1021/acs.jproteome.0c00847.
14.Yang DH, Liu S, Cao L, Zheng YD, Huang JF, Ge R, He QY, Sun X. Quantitative secretome analysis of polymyxin B resistance in Escherichia coli. Biochem Biophys Res Commun. 2020, 530(1), 307-313. doi: 10.1016/j.bbrc.2020.07.010.
15.Du GF, Le YJ, Sun X, Yang XY, He QY. Proteomic investigation into the action mechanism of berberine against Streptococcus pyogenes. J Proteomics.2020, 215, 103666. doi: 10.1016/j.jprot.2020.103666.
16.Du GF, Zheng YD, Chen J, He QY, Sun X. Novel Mechanistic Insights into Bacterial Fluoroquinolone Resistance. J Proteome Res. 2019, 18(11), 3955-3966. doi: 10.1021/acs.jproteome.9b00410.
17.Shi T, Wei Q, Wang Z, Zhang G, Sun X, He QY. Photocatalytic Protein Damage by Silver Nanoparticles Circumvents Bacterial Stress Response and Multidrug Resistance. mSphere. 2019, 4(3), e00175-19. doi: 10.1128/mSphere.00175-19.
18.Han J, Yi S, Zhao X, Zheng Y, Yang D, Du G, Yang XY, He QY, Sun X. Improved SILAC method for double labeling of bacterial proteome. J Proteomics. 2019, 194, 89-98. doi: 10.1016/j.jprot.2018.12.011.
19.Cao K, Lai F, Zhao XL, Wei QX, Miao XY, Ge R, He QY, Sun X. The mechanism of iron-compensation for manganese deficiency of Streptococcus pneumoniae. J Proteomics. 2018, 184, 62-70. doi: 10.1016/j.jprot.2018.06.004.
20.Miao X, He J, Zhang L, Zhao X, Ge R, He QY, Sun X. A Novel Iron Transporter SPD_1590 in Streptococcus pneumoniae Contributing to Bacterial Virulence Properties. Front Microbiol. 2018, 9, 1624. doi: 10.3389/fmicb.2018.01624.
21.Cao K, Zhang J, Miao XY, Wei QX, Zhao XL, He QY, Sun X. Evolution and molecular mechanism of PitAs in iron transport of Streptococcus species. J Inorg Biochem. 2018, 182, 113-123. doi: 10.1016/j.jinorgbio.2018.02.006.
22.Liu YT, Pan Y, Lai F, Yin XF, Ge R, He QY, Sun X. Comprehensive analysis of the lysine acetylome and its potential regulatory roles in the virulence of Streptococcus pneumoniae. J Proteomics. 2018, 176, 46-55. doi: 10.1016/j.jprot.2018.01.014.
23.Yang XY, He K, Du G, Wu X, Yu G, Pan Y, Zhang G, Sun X, He QY. Integrated Translatomics with Proteomics to Identify Novel Iron-Transporting Proteins in Streptococcus pneumoniae. Front Microbiol. 2016, 7, 78. doi: 10.3389/fmicb.2016.00078.
24.Guo Z, Han J, Yang XY, Cao K, He K, Du G, Zeng G, Zhang L, Yu G, Sun Z, He QY, Sun X. Proteomic analysis of the copper resistance of Streptococcus pneumoniae. Metallomics. 2015, 7(3), 448-54. doi: 10.1039/c4mt00276h.
25.Yang XY, Zhang L, Liu J, Li N, Yu G, Cao K, Han J, Zeng G, Pan Y, Sun X, He QY. Proteomic analysis on the antibacterial activity of a Ru(II) complex against Streptococcus pneumoniae. J Proteomics. 2015, 115, 107-116. doi: 10.1016/j.jprot.2014.11.018.