1.Yi W #, Zhang J #, Huang Y#, Zhan Q, Zou M, Cheng X, Zhang X, Yin Z, Tao S, Cheng H, Wang F, Guo J*, Ju Z*, Chen Z*. Ferritin-Mediated Mitochondrial Iron Homeostasis is essential for the Survival of Hematopoietic Stem Cells and Leukemic Stem Cells. Leukemia. 2024. doi: 10.1038/s41375-024-02169-y. Online ahead of print. (影响因子 11.4)
2.Duan W, Ou Z, Huang Y, Zhang Y, Zhang L, Zhao Y, He R, Zhang Y, Ge Y, Lou H*, Ju Z*, Hu Q*. Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries. Antioxidants (Basel). 2023 Dec 15;12(12):2119. （影响因子7.0）
3.Aging Biomarker Consortium, Mengmeng Jiang*, et al, Ju Z*, et al, Yunfang Wang*. A biomarker framework for liver aging: the Aging Biomarker Consortium consensus statement. Life Medicine. 2024 :lnae004.
4.Aging Biomarker Consortium, Le Zhang*, et al, Ju Z*, et al,,Cuntai Zhang*, A framework of biomarkers for vascular aging: a consensus statement by the Aging Biomarker Consortium. Life Medicine .Volume 2, Issue 4, August 2023: lnad033.
5.Aging Biomarker Consortium; Bao H*, et al, Ju Z*, et al, Liu GH*. Biomarkers of aging. Sci China Life Sci. 2023 May;66(5):893-1066.（影响因子10.384）
6.Liu J#, Zuo H#, Wang Z#, Wang W, Qian X, Xie Y, Peng D, Xie Y, Hong L, You W, Lou H, Luo G, Ren J, Shen B, Zheng J *, Wang H *, Ju Z *. The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K-Akt-mTOR signalling. Cell Proliferation. 2023 Feb 1:e13410. (影响因子8. 5)
7.Zhang K#, Liu D#, Li Y, Shi Z, Guo J, Gao C, Wang H, Ju Z*, Diao D*. The E3 ligase TRIM31 regulates hematopoietic stem cell homeostasis and MLL-AF9 leukemia. Haematologica. 2023 Aug 1;108(8):2116-2129. (影响因子 11.4)
8.Liu B*#, Zhou YY#, Wu QF, Fu YT, Zhang XL, Wang ZK, Yi WW, Wang H, Chen ZY, Song ZF, Xiong W, Qiu YG, He WF*, and Ju Z*. EVA1A regulates hematopoietic stem cell regeneration via ER-mitochondria mediated apoptosis. Cell Death & Dis. 2023, 14(1):71. (影响因子: 9.0)
9.Zhang L*, Li Y, Wang Y, Qiu Y, Mou H, Deng Y, Yao J, Xia Z, Zhang W, Zhu D, Qiu Z, Lu Z, Wang J, Yang Z, Mao G, Chen D, Sun L, Liu L*, Ju Z*. mTORC2 Facilitates Liver Regeneration Through Sphingolipid-Induced PPAR-α-Fatty Acid Oxidation. Cell Mol Gastroenterol Hepatol. 2022;14(6):1311-1331.(影响因子 7.2)
10.Wu S#, Ge Y#*, Lin K, Liu Q, Zhou H, Hu Q, Zhao Y, He W*, Ju Z*. Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity. Nucleic Acids Res. 2022 Apr 22;50(7):3764-3776. (影响因子 14.9)
11.Ma XR, Zhu X, Xiao Y, Gu HM, Zheng SS, Li L, Wang F, Dong ZJ, Wang DX, Wu Y, Yang C, Jiang W, Yao K, Yin Y, Zhang Y, Peng C, Gao L, Meng Z, Hu Z, Liu C, Li L, Chen HZ*, Shu Y*, Ju Z*, Zhao JW*. Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing. Nat Commun. 2022 Mar 9;13(1):1225. (影响因子 16.6)
12.Pan Y#, Zuo H#, Wen F, Huang F, Zhu Y, Cao L, Sha QQ, Li Y, Zhang H, Shi M, Liang C, Huang J, Zou L, Fan HY, Ju Z*, Wang H*, Shen L*. HMCES safeguards genome integrity and long-term self-renewal of hematopoietic stem cells during stress responses. Leukemia. 2022 Apr;36(4):1123-1131. (影响因子11.4)
13.Zhu X#, Chen Z#, Shen W, Huang G, Sedivy JM, Wang H*, Ju Z*. Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention. Signal Transduct Target Ther. 2021 Jun 28;6(1):245. (影响因子39.3)
14.Zhou Y, Wang Z, Huang Y, Bai C, Zhang X, Fang M, Ju Z*, Liu B*. Membrane dynamics of ATG4B and LC3 in autophagosome formation. J Mol Cell Biol. 2022 Jan 29;13(12):853-863. (影响因子 5.5)
15.Hu Q*, Zhang Y, Lou H, Ou Z, Liu J, Duan W, Wang H, Ge Y, Min J, Wang F*, Ju Z*(co-corresponding). GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis. Cell Death Dis. 2021 Jul 15;12(7):706. (影响因子 9.0)
16.He W, Wang X, Ni Y, Li Z, Liu W, Chang Z, Li H, Ju Z*(co-corresponding), Li Z*. Wip1 regulates hematopoietic stem cell development in the mouse embryo. Haematologica. 2021 Feb 1;106(2):580-584. (影响因子 10.1)
17.Shi Z, Diao D*, Zhao Y, Luo Y, Li Y, Liu D, Zhang K, Qiu Y, Song Z, Ju Z*(co-corresponding). C/EBP homologous protein deficiency enhances hematopoietic stem cell function via reducing TF3/ROS-induced cell apoptosis. Aging Cell. 2021 Jun 15; e13382. doi: 10.1111/acel.13382. (影响因子 7.8)
18.Le R*, Huang Y, Zhang Y, Wang H, Lin J, Dong Y, Li Z, Guo M, Kou X, Zhao Y, Zhao A, Chen M, Zhu Q, Yin J, Sun J, Su Z, Shi K, Gao Y, Chen J, Kang L, Wang Y, Li C, Wang H, Ju Z*(co-corresponding), Gao S*. Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells. Cell Stem Cell. 2021 Apr 1;28(4):732-747.e9. (影响因子 23.9)
19.Yi W, Zhang Y, Liu Bo*, Zhou Y, Liao D, Qiao X, Gao D, Xie T, Yao Q, Zhang Yao, Qiu Y, Huang G, Chen Z*, Chen C*, Ju Z*(co-corresponding). Protein S-nitrosylation Regulates Proteostasis and Viability of Hematopoietic Stem Cell during Regeneration. Cell Rep. 2021 Mar 30;34(13):108922. (影响因子 8.8)
20.Zhang L, Qiu Y, Yang F, Yao J, Wang Y, Qin Y, Mou H, Jing Q*, Liu L*, Ju Z* (co-corresponding). Hepatic microRNA-126 Deficiency Restrains Liver Regeneration Through p53 Pathway In Mice. Signal Transduction and Targeted Therapy. 2021 Jan 28;6(1):32. doi: 10.1038/s41392-020-00395-1. (影响因子 39.3）
21.Wang Y*, Zheng JP, Luo Y, Wang J, Xu L, Wang J, Sedivy JM, Song Z*, Wang H*, Ju Z*(co-corresponding). L1 drives HSC aging and affects prognosis of chronic myelomonocytic leukemia. Signal Transduction and Targeted Therapy. 2020 Sep 19;5(1):205. (影响因子 39.3）
22.Han B, Jiang W, Liu H, Wang J, Zheng K, Cui P, Feng Y, Dang C, Bu Y, Wang QM, Ju Z*(co-corresponding), Hao J*. Upregulation of neuronal PGC-1α ameliorates cognitive impairment induced by chronic cerebral hypoperfusion. Theranostics. 2020 Feb 3;10(6):2832-2848. (影响因子12.4)
23.Zhu X*, Shen W, Yao K, Wang H, Liu B, Li T, Song L, Diao D, Mao G, Huang P, Li C, Zhang H, Zou Y, Qiu Y, Zhao Y, Wang W, Yang Y, Hu Z, Auwerx J, Loscalzo J, Zhou Y*, Ju Z*(co-corresponding). Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity. Circulation Research. 2019 Sep 13;125(7):707-719. (影响因子 20.1)
24.Wang X, Gao Y, Gao J, Li M, Zhou M, Wang J, Pang Y, Cheng H, Yuan C, Chu Y, Jiang Y, Zhou J, Luo HR, Ju Z*(co-corresponding), Cheng T*, Yuan W*. Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo. Haematologica. 2019 Feb;104(2):245-255. (影响因子 11.047)
25.Yang F, Huang Y, Chen X, Liu L, Liao D, Zhang H, Huang G, Liu W, Zhu X, Wang W, Lobo CA, Yazdanbakhsh K, An X, Ju Z*. Deletion of a flippase subunit Tmem30a in hematopoietic cells impairs mouse fetal liver erythropoiesis. Haematologica. 2019 Feb 28; 104(10):1984-1994. (影响因子 11.047)
26.Wang H*, Zuo H, Liu J, Wen F, Gao Y, Zhu X, Liu B, Xiao F, Wang W, Huang G, Shen B*, Ju Z*(co-corresponding). Loss of YTHDF2 mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration. Cell Res. 2018 Oct;28(10):1035-1038. (影响因子 46.297)
27.Diao D*, Wang H, Li T, Shi Z, Jin X, Sperka T, Zhu X, Zhang M, Yang F, Cong Y, Shen L, Zhan Q, Yan J, Song Z, Ju Z*. Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan. EMBO Rep. 2018 Oct;19(10). pii: e45494. (影响因子 9.071)
28.Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M,Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Myriam Gorospe, Ju Z* (co-corresponding), Wang W*. HuR regulates telomerase activity through TERC methylation. Nat Commun 2018 Jun 7;9(1):2213. (影响因子 17.694)
29.Kang Y, Zhang H, Zhao Y, Wang Y, Wang W, He Y, Zhang W, Zhang W, Zhu X, Zhou Y, Zhang L, Ju Z*(co-corresponding), Shi L*. Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1α/TNFAIP3 Axis. Cell Rep. 2018 Mar 27;22(13):3493-3506. (影响因子 9.995)
30.Zhang C, Yi W, Li F, Du X, Wang H, Wu P, Peng C, Luo M, Hua W, Wong CC, Lee JJ, Li W, Chen Z, Ying S*, Ju Z*(co-corresponding), Shen H*. Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis. Cell Res. 2018 Mar; 28(3):323-335. (影响因子 46.297)
31.Zhu X, Shen W, Wang Y, Jaiswal A, Ju Z*(co-corresponding), Sheng Q*. Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice. Signal Transduction and Targeted Therapy .2017 Jul 7;2: 17017. (影响因子 38.104)
32.Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, Chen H, Wang M, Ju Z*(co-corresponding), Cong Y*. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1a stability. Nat Commun 2017 Jan 27;8:14186. (影响因子 17.694)
33.Wang H*, Diao D, Shi Z, Zhu X, Gao Y, Gao S, Liu X, Wu Y, Rudolph KL,Liu G, LiT, JuZ*(co-corresponding). SIRT6 Controls Hematopoietic Stem Cell Homeostasis through the Epigenetic Regulation of Wnt Signaling. Cell Stem Cell. 2016 Apr 7;18(4):495-507. (影响因子 25.269)
34.Yi W, Hu X, Chen Z, Liu L, Tian Y, Chen H, Cong YS, Yang F, Zhang L, Rudolph KL, Zhang Z, Zhao Y*, Ju Z*(co-corresponding). Phosphatase Wip1 controls antigen-independent B cell development in a p53-dependent manner. Blood. 2015 Jul 30;126(5):620-8. (影响因子 25.476)
35.Chen Z, Yi W, Morita Y, Wang H, Cong Y, Liu JP, Xiao Z, Rudolph KL, Cheng T, Ju Z*(corresponding). Wip1-deficiency Impairs Hematopoietic Stem Cell Function via p53 and mTORC1 Pathways. Nature Commun. 2015 Apr 16;6:6808. doi: 10.1038/ncomms7808. (影响因子 17.694)
36.Zhang L, Liu L, He Z, Li G, Liu J, Song Z, Jin H, Rudolph KL, Yang H, Mao Y, Zhang L, Zhang H, Xiao Z, Ju Z*(corresponding). Inhibition of Wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mTOR. Hepatology. 2015 Jun;61(6):2030-41. (影响因子17.298)
37.ChenY ,Ma X, Zhang M, Wang X, Wang C, Wang H, Guo P, Yuan W,Rudolph KL,Zhan Q, Ju Z*(corresponding). Gadd45a Regulates Hematopoietic Stem Cell Stress Responses in Mice. Blood. 2014 Feb 6;123(6):851-62. (影响因子 25.476)
38.Chen Y, Yang R, Guo P, Ju Z*(corresponding). Gadd45a Deletion Aggravates Hematopoietic Stem Cell Dysfunction in ATM-deficient Mice. Protein Cell. 2014 Jan 29 ;5(1):80-9. (影响因子 15.328)
39.Le R, Kou Z, Jiang Y, Li M, Huang B, Liu W, Li H, Kou X, He W, Rudolph KL, Ju Z*(co-corresponding), Gao S*. Enhanced Telomere Rejuvenation in Pluripotent Cells Reprogrammed via Nuclear Transfer Relative to Induced Pluripotent Stem Cells. Cell Stem Cell. 2014 Jan 2;14(1):27-39. (影响因子 25.269)
40.Li Z, Lan Y, He W, Chen D, Wang J, Zhou F, Wang Y, Sun H, Chen X, Xu C, Li S, Pang Y, Zhang G, Yang L, Zhu L, Fan M, Shang A, Ju Z, Luo L, Ding Y, Guo W,Yuan W, Yang X, Liu B. Mouse embryonic head as a site for hematopoietic stem cell development. Cell Stem Cell. 2012 Nov 2;11(5):663-75. (影响因子 25.269)
41.Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell. 2012 Mar 2;148(5):1001-14. (影响因子 66.85)
42.Song Z, Zhang J, Ju Z*(co-corresponding), Rudolph KL*. Telomere dysfunctional environment induces loss of quiescence and Inherent impairments of hematopoietic stem cell function. Aging Cell. 2012 Jun;11(3):449-55. (影响因子 9.304)
43.Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A, Begus-Nahrmann Y, Burkhalter MD, Mach M, Schlaudraff F, Liss B, Ju Z, Speicher MR,Rudolph KL. Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction. Nat Cell Biol. 2011 Dec 4;14(1):73-9. (影响因子 28.213)
44.Xiao F, Zheng X, Cui M, Shi G, Chen X, Li R, Song Z, Rudolph KL, Chen B*, Ju Z*(co-corresponding). Telomere dysfunction-related serological markers are associated with type 2 diabetes. Diabetes Care. 2011 Oct;34(10):2273-8. (影响因子 17.152)
45.Song Z, Wang J, Guachalla LM, Terszowski G, Rodewald HR, Ju Z*(co-corresponding), Rudolph KL*. Alterations of the systemic environment are the primary cause of impaired B and T lymphopoiesis in telomere-dysfunctional mice. Blood. 2010 Feb 25; 115(8):1481-9. (影响因子25.476)
46.Yang Z, Huang X, Jiang H, Zhang Y, Liu H, Qin C, Eisner GM, Jose PA, Rudolph KL, Ju Z*(corresponding). Short Telomeres and Prognosis of Hypertension in a Chinese Population. Hypertension. 2009 Apr;53(4):639-45. (影响因子 9.897)
47.Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR, Clark AB, Rudolph C, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA, Greenberg RA, Edelmann W, Rudolph KL. Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. Cell .2007 Sep 7;130(5):863-77. (影响因子 66.85)
48.Ju Z, Hong J, Jaworski M, Gompf A, Rathinam C, Klein C, Trumpp A, Rudolph KL. Telomere dysfunction induces environmental defects limiting hematopoietic stem cell function and engraftment. Nature Medicine. 2007 Jun;13(6):742-7. (影响因子 87.241)
49.Choudhury AR, Ju Z(co-first), Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. Nature Genetics. 2007 Jan, 39(1):99-105. (影响因子 41.307)