第一作者及通讯作者论文:
1. Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer. EMBO Molecular Medicine (IF: 12.137).
2. Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer. (2021). Theranostics (IF: 11.556).
3. Mitochondria-targeted magnetic gold nanoheterostructure for multi-modal imaging guided photothermal and photodynamic therapy of triple-negative breast cancer. (2021). Chemical Engineering Journal (IF:13.273).
4. A tumor suppressor enhancing module orchestrated by GATA4 denotes a therapeutic opportunity for GATA4 deficient HCC patients. (2020). Theranostics (IF: 11.556).
5. Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-B signaling axis in lung cancer cells and denotes a therapeutic opportunity. (2020). Theranostics (IF: 11.556).
6. IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function. (2019) Cell Cycle (IF: 4.534).
7. Discovery of Novel Inhibitor for WNT/b-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening. (2020). Molecules (IF: 4.411).
8. The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling. (2014). Cell Host Microbe (IF: 21.023).
9. Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms. (2012). Cell Research (IF: 25.617).
主要合作研究论文
10. ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association. (2017). Cellular & Molecular Immunology (A1-2, IF: 8.213).
11. Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors. (2020). EMBO Molecular Medicine (A1-1, IF: 12.137).
12. Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition. (2019). Nature communications (A1-1, IF: 12.118).
13. TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction. (2017). J Immunol (A1-2, IF: 4.718).
14. MHC class I-related molecule, MR1, and mucosal-associated invariant T cells. (2016). Immunological reviews (A1-1, IF: 6.35).
15. LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. (2012). PNAS (A1-1,IF: 9.58).
16. SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. (2011). Journal of Molecular Cell Biology (A1-2,IF: 13.4).
17. The E3 ubiquitin ligase MARCH8 negatively regulates IL-1beta-induced NF-kappaB activation by targeting the IL1RAP coreceptor for ubiquitination and degradation. (2012). PNAS (A1-1,IF: 9.58).
18. SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. (2011). Journal of Molecular Cell Biology (A1-2,IF: 13.4).