个人信息 |
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姓名: 陈静 部门: 生命科学技术学院 性别: 女 职务: 无 职称: 学位: 博士 毕业院校: 韩国中央大学 联系电话: 13318845346 电子邮箱: chenj@jnu.edu.cn 办公地址: 第二理工楼641 通讯地址: 广州市天河区黄埔大道西610号暨南大学第二理工楼 邮编: 传真: 荣誉奖励: |
联系方式邮箱:chenj@jnu.edu.cn 电话:13318845346 |
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个人简介学习经历2008-2012 年 陕西科技大学 食品科学与工程专业学士 2012-2015 年 南昌大学 食品科学硕士 2015-2020 年 韩国中央大学 食品化学博士 工作经历2020-2025 年 暨南大学 先进与应用化合合成研究院 2025-至今 暨南大学 生命科学技术学院食品科学与工程专业 研究方向方向一:构建结构脂质“理化性质-消化行为-代谢特点-健康效应”研究体系,挖掘结构脂质改善体内脂质代谢紊乱作用,并进一步明晰体内调节机制。 方向二:挖掘脂质生物活性分子,探明其构效关系;构建靶向递送体系,实现脂质生物活性分子高效利用。 主要论文1.A novel synergistic inhibition mechanism of pancreatic lipase by 2-mercaptobenzothiazole and ste aric acid migrants from dairy contact rubbers. Food Chemistry 2025, 479, 143816.(中科院 一区 top)(通讯作者) 2.Raffinose esters of long-chain unsaturated fatty acids: Preparation, characterization, and in vitro digestive behavior. Food Research International 2025, 116772.(中科院 一区 top)(通讯作者) 3.Flaxseed Linusor b Alleviates Collagen-Induced Rheumatoid Arthritis in Rats via Inhibiting the TLR4/N F-κb/MAPK Signal Pathway and Modulating Gut Microbiota. Journal of Agricultural and Food Chemistry 2024,72, 27991-28004. (中科院一区 top) (共一) 4.Risk assessment of migrants released from multilayer packaging materials: Direct immersion-solid-phase microextraction coupled to gas chromatography-mass spectrometry. Food Packaging and Shelf Life 2024, 46, 101407. (中科院一区 top) (通讯作者) 5.Novel biopolymer-based a ctive packaging material for food applications: Cinnamaldehyde-loaded calcium nanopar ticles incorporated into alginate-carboxymethyl cellulose films. Food Packaging and S helf Life 2024, 45, 101351. (中科院一区 top)(通讯作者) 6.Impact of 2,4-di-tert-butylphenol on pancreatic lipase activity in emulsions: Multispectral, molecular docking, and in vitro digestion analysis. Food Chemistry 2025, 470, 142730. (中 科院一区 top)(通讯作者) 7.The effect of flaxseed oil after deep frying on lipid metabolism and gut barrier homeostasis. Food Research International 2024, 175, 113728. (中科院一区)(通讯作者) 8.Visible light-mediated syntheses of unsymmetrical methylene-bridged bis-heterocycles vi a an alkoxy radical relay reaction. Organic Chemistry Frontiers 2023,10(18), 4649-4657. (中科院一区)(通讯作者) 9. Solasodine suppress MCF7 breast cancer stem-like cells via targeting Hedgehog/Gli1. Phytomedicine 2022, 154448. (中科院一区)(第一作者) 10.Control release of α-mangostin by a novel dual-polysaccharides delivery system for colitis treatm ent nder simulated gastrointestinal conditions. Food Bioscience 2023, 102531. (中科院一 区)(通讯作者) 11. Garcinone C Suppresses Tumorsphere Formation and Invasiveness by Hedgehog/ Gli1 Signaling in Colorectal Cancer Stem-like Cells. Journal of Agricultural and Food Chemistry 2022, 70(26), 7941-7952. (中科院一区Top)(通讯作者) 12.β-Thujaplicin inhibits basal-like mammary tumor growth by regulating glycogen synthase kinase-3β/β-catenin signaling. Food & Function, 2019,10(5), 2691-2700. (中科院一区)(第一作者) 13. Amentofla vone inhibits tumor necrosis factor-α-induced migration and invasion through AKT/mT OR/S6k1/hedgehog signaling in human breast cancer. Food & Function 2021, 12, 10196-10 209. (中科院一区Top) (通讯作者) 14.Sulforaphe ne inhibition of adipogenesis via hedgehog signaling in 3T3-L1 adipocytes. Journal of Agricultural and Food Chemistry, 2,018, 66(45), 11926-11934. (中科院一区)(第一作者) 15. Garcinone C suppresses colon tumorigenesis through the Gli1-dependent hedgehog signaling pathway. Phytomedicine 2020, 79, 153334. (中科院一区Top) (第一作者) | 16. Chitosan-bas ed bone-targeted nanoparticles delivery of cyclolinopeptide J for the synergistic treatm ent of osteoporosis. International Journal of Biological Macromolecules 2025,304, 140884. (中科院二区 top) (通讯作者) 17.The mechanistic study of diacylglycerol in ameliorating no-nalcoholic fatty liver and systemic lipid accumulation. Journal of Functional Foods,2024,121,106373.(中科院二区 )(通讯作者) 18.The synergistic treatment of cyclolinopeptide J and calcium carbonate nanoparticles for osteoporosis via BMP/Wnt signaling: In vivo and in vitro. Journal of Functional Foods,2023,110, 105826. (中科院二区 top)(通讯作者) 19.Investigating the impact of common migration substances found in milk packaging on proteases: A multispectral and molecular docking approach. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024,124517. (中科院二区)(通讯作者) 20.The Lipid-Metabolism-Associated Anti-Obesity Properties of Rapeseed Diacylglycerol Oil. Nutrients,2024,,16(13), 2003. (中科院二区)(通讯作者) 主要著作《甘油二酯油与人体健康》副主编 承担课题1. 棕榈油结构脂质及脂质生物活性分子健康效应和功效机制研究,2024YFE0214900,国家重点研发计划战略性科技创新合作项目课题,科技部。经费84万元,2025-01至2026-12。 2.ω-3多不饱和脂肪酸棉子糖单酯对肠道屏障影响机制研究,32201933,青年科学基金项目(C类),国家自然科学基金委员会。经费30万,2023-01至2025-12. 3.亚麻籽甘油二酯消化性质及对肠道稳态机制研究,2025A1515012137,广东省自然科学基金-面上项目,广东省科技厅。经费 10万,2025-01至2027-12。 4.ω-3多不饱和脂肪酸棉子糖单酯 酶法制备及对肠道生物屏障影响机制研究,2023A1515010559,广东省自然科学基金-面上项目,广东省科技厅。经费10万,2023-01至2025-12。 5.主要农作物种植及其农副产品加工技术与推广,KTP20240705,广东省科技项目,广东省科技厅,经费30万元,2024-09至2027-08。 6.玉桂精深加工及其产产业化示范应用及推广,KTP20210410,广东省科技项目,广东省科技厅,经费30万元,2022-01至2024-12。 7.ω-3多不饱和脂肪酸-糖单酯酶法制备及消化性质研究,202102,农业农村部油料加工重点研究室-开放项目,经费5万,2022-03至2024-03。 8.ω-3多不饱和脂肪酸-棉子糖单酯制备及消化性质研究,202201010170,广州市基础与应用基础项目,经费5万,2021-01至2023-12. 9.肉桂深加工技术的推广与应用,KTP20200021,广东省科技项目,广东省科技厅,经费10万元,2020-7至2021-12。 发明专利1. 一种能够预防和治疗脂肪肝的甘油二酯油的制备方法及应用,程凯,陈静,程建强,专利号ZL20250131095.9. 2.一种亚麻籽环肽骨靶向纳米递送体系的制备方法及应用,汪勇,陈佳子,陈静,蔡子哲,李雯,专利号ZL202310792754.4 讲授课程本科生课程:《食品创新与发展》全英授课 研究生课程:《高级食品化学》 荣誉奖励社会职务担任SCI期刊《Traditional Medicine Research》、《中国油脂》期刊青年编委 |