个人信息

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姓名: 李旭升

部门: 生命科学技术学院

性别:

职务: 食品系研究生第一党支部书记

职称:

学位: 工学博士

毕业院校: 暨南大学

联系电话:

电子邮箱: lixusheng1016@163.com

办公地址:

通讯地址: 广东省广州市天河区暨南大学第二理工楼458

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传真:

荣誉奖励:

联系方式

E-mail: lixusheng1016@163.com



个人简介

李旭升,博士,暨南大学生命科学技术学院,副研究员,博士研究生导师。主要研究方向为膳食花色苷对生殖损伤及代际遗传的干预调控作用;花色苷及富含花色苷食品加工过程中的稳态化及营养功能。主持国家自然科学基金、国家重点研发计划子课题、广东省自然科学基金面上项目、广州市重点研发计划、中国博士后科学基金面上资助、广东省农村科技特派员项目等10项基金项目。获批果酒科创高层次人才,担任《食品研究与开发》青年编委,多个国际期刊审稿人。相关研究成果已在国内外权威期刊发表论文70余篇,其中第一作者或通讯作者在Journal of Advanced ResearchJournal of Hazardous Materials, Journal of Agricultural and Food Chemistry, Food Chemistry, Comprehensive Reviews in Food Science and Food SafetyCritical Reviews in Food Science and Nutrition 等顶级期刊发表论文34篇(高被引论文2篇,热点论文1篇),H-index 27;此外还参与申请专利23项,授权6项。


学习经历

2016.9-2019.6 暨南大学 食品科学 硕士

2018.11-2019.4 University of Kentucky 分子生物学 访问交流

2019.9-2022.6 暨南大学 生物医学物理与生物医学信息技术 博士




工作经历

2022.7-2024.6 暨南大学附属第六医院 博士后,助理研究员

2024.7-至今 暨南大学 食品科学与工程系 副研究员



研究方向

[1] 生殖损伤及不良代际遗传的膳食干预

[2] 花色苷稳态化及生物活性

主要论文

1.       Hu J. H., Tan S. Q., Zhang L., Jiao R., Li   X. S. (co-corresponding author),   Bai W. B. Divergent modulation of blueberry vinegar volatile flavor profile   by ultrasound and ultra-high pressure processing. Journal of Food Process   Engineering, 2026, 49: e70337.

2.       Cai D. B., Li Y. X., Sun D. W., Bai W. B., Li   X. S. (corresponding author).   Anthocyanin-mediated epigenetic modifications: a new perspective in health   promoting and disease prevention.   Journal of Advanced Research, 2026. 85: 1099-1117.

3.       Liu X. Y., Li X. S. (co-first author), Cai D. B., Sun J. X., Bai W. B. Dietary patterns and testosterone   balance: a review of clinical data and perspectives. Journal of Advanced   Research, 2025. DOI:10.1016/j.jare.2025.11.016.

4.       Ye M. J., Zuo L., Li X. S. (co-first author), Sun D. W., Xu X. H., Huang S.   Q., Bai W. B. Aronia melanocarpa anthocyanins attenuate light-induced retinal   damage by enhancing photoreceptor cell function and anti-inflammatory effects.   Food & Function. 2025, 16: 8496-8514.

5.       Zuo L., Ye M. J., Chen L., Xu X. H., Huang S.   Q., Li X. S.   (corresponding author), Bai W. B. Anthocyanin-rich berries and their bioactive   compounds in ocular health: Mechanisms and therapeutic potential. Journal of Agricultural and Food Chemistry.   2025, 73: 23724-23741.

6.       Li Y. X., Liu L. W., Zhang Y. L., Bai S.,   Jiang Y., Lai C. Y., Li X. S. (co-corresponding author), Bai W. B. Paternal cyanidin-3-O-glucoside   diet improved high-Fat, high-Fructose diet-induced intergenerational inheritance   in male offspring's susceptibility to high-fat diet-induced testicular and sperm   damage. Reproductive Sciences. 2025, 32: 1102-1114.

7.     Han Y. D.,   Li X. S. (co-first author),   Zhang Q., Zhou W. J., Wu G. K., Yuan K. L., Cui C. B., Bai W. B. Lactobacillus   fermentation accelerated biotransformation of cranberry anthocyanins   towards phenol-pyranoanthocyanins and their stability and antioxidant   property. Food Chemistry. 2024, 461: 140793.

8.       Yuan K. L., Li X. S. (co-first author), Zeng Y. Y., Liu C. Q., Zhu Y.   Q., Hu J., Sun J. X., Bai W. B. Chemical stability of   carboxylpyranocyanidin-3-O-glucoside under β-glucosidase treatment and   description of their interaction. Food Chemistry. 2024, 447: 138840.

9.       Li X. S., Wang Y. X., Jiang   Y., Liu C. Q., Zhang W. B., Chen W. W., Tian L. M., Sun J. X., Lai C. Y., Bai   W. B. Microencapsulation with fructooligosaccharides and whey protein   enhances the antioxidant activity of anthocyanins and their ability to   modulate gut microbiota in vitro. Food Research International. 2024, 181:   114082.

10.    Jiang Y., Li X. S. (co-first author), Zhang Y. L., Wu B. Y., Li Y.   X., Tian L. M., Sun J. X., Bai W. B. Mechanism of action of anthocyanin on   detoxification of foodborne contaminants—A review of recent literature. Comprehensive Reviews in Food Science and   FoodSafety. 2024,   23: 1-33.

11.    Zhang W. B.,Li X. S. (co-first author), Ma X. Q., Li H. Y., Liu J.,   Zeng Y. Y., Cai D. B., Xu Q. J., Chen G. B., Tian L. M., Sun J. X., Bai W. B.   Microencapsulation of anthocyanins extracted from black soybean peels by whey   protein/fructo-oligosaccharide contributes to improved stability, bioavailability,   and in vivo bioactivity. Food Frontiers.   2023: 1-14.

12.    Li X. S., Yuan K.   L., Zhang Y. L., Liu C. Q., Cai D. B., Sun J. X., Lai C. Y., Bai W. B. The   promising stability of carboxylpyranocyanidin-3-O-glucoside during food   processing and simulated digestion and its bioavailability research. Journal of the Science of Food and   Agriculture. 2023, 104: 13122.

13.    Liu C. Q., Li X. S. (co-first author), Zeng Y. Y., Liang S. Y., Sun   J. X., Bai W. B. Interaction between a commercial mannoprotein and   cyanidin-3-O-glucoside-4-vinylphenol and its stability and antioxidative   properties as a novel functional pigment.Journal of Agricultural and Food Chemistry. 2023, 71,   17163-17174.

14.    Li X. S., Li Z. H., Cai D.   B., Li Y. W., Zhu Y. Q., Jiao R., Lai C. Y., Sun J. X., Bai W. B. Vitisin A,   as a type of pyranoanthocyanin, suppresses inflammation by restricting   hematopoietic stem cell differentiation toward monocytes in bone marrow. Journal of Agricultural and Food Chemistry.   2023, 71: 15048-15063.

15.    Li X. S., Liu C. Q., Li Y.   W., Yuan K. L., Zhang W. B., Cai D. B., Peng Z. Y., Hu Y. F., Sun J. X., Bai   W. B., Bioactivity and application of anthocyanins in skin protection and   cosmetics: an extension as a functional pigment. Phytochemistry Reviews. 2023

16.    Hu X., Li   X. S. (co-first author), Deng P., Zhang Y. L., Liu R. J., Cai D. B.,   Xu Q. J., Jiang X. W., Sun J. X., Bai. W. B. The consequence and mechanism of   dietary flavonoids on androgen profiles and disorders amelioration. Critical Reviews in Food Science and   Nutrition., 2023, 63:   11327-11350.

17.    Hu J., Li   X. S. (co-first author), Wu N. J., Zhu C. J., Jiang X. W., Yuan K.   L., Li Y., Sun J. X., Bai W. B. Anthocyanins prevent AAPH-induced   steroidogenesis disorder in Leydig cells by counteracting oxidative stress   and StAR abnormal expression in a structure-dependent manner. Antioxidants. 2023, 12: 508.

18.    Liang S. E., Li X. S. (co-first author), Liu R. J., Hu J., Li Y., Sun   J. X., Bai W. B. Malvidin-3-O-glucoside ameliorates cadmium-mediated cell   dysfunction in the estradiol generation of human granulosa cells. Nutrients, 2023, 15: 753.

19.    Zeng Y. Y., Li X. S. (co-first author), Yuan K. L., Chen B., Zhang W.   B., Sun J. X., Ramaswamy H. S., Bai W. B. Formation of   hydroxyphenyl-pyranoanthocyanins derived from cyanidin-3-O-glucoside and   effects of high-pressure processing on the transformation efficiency. Food Chemistry, 2023, 408: 135247.

20.    Zhao Y. Q., Zeng Y. Y., Li X. S. (co-first author), Yuan K. L., Li Y., Tian L. M.,   Sun J. X., Bai W. B. Modeling and application of sensory evaluation of   blueberry wine based on principal component analysis. Current Research in Food Science, 2023, 6: 100403.

21.    Wu Z. Q., Li X. S. (co-first author), Zeng Y. Y., Cai D. B., Teng Z.   J., Wu Q. X., Sun J. X., Bai W. B. Color stability enhancement and   antioxidation improvement of Sanhua Plum wine under circulating ultrasound. Foods. 2022, 11: 2435.

22.    Cai D. B., Li X. S. (co-first author), Chen J. L., Jiang X. W., Ma X.   Q., Sun J. X., Tian L. M., Vidyarthi S. K., Xu J. W., Bai W. B. A   comprehensive review on innovative and advanced stabilization approaches of   anthocyanin by modifying structure and controlling environmental factors. Food Chemistry, 2022, 366: 130611.

23.    Li X. S., Teng Z.   J., Luo Z. Y., Yuan Y. B., Zeng Y. Y., Hu J., Sun J. X., Bai W. B. Pyruvic   acid stress caused color attenuation by interfering with anthocyanins   metabolism during alcoholic fermentation.   Food Chemistry, 2022, 372: 131251.

24.    Wang X. H.,Li X. S. (co-first author), Liu Y. X., Jiang X. H., Wu L.   M., Liu R., Jin R. T., Zhou N. R., Cao C., Hu X. C., Xu B., Tong X. H., Bai   W. B., Bai S. Cyanidin-3-Ο-glucoside supplementation in cryopreservation medium   improves human sperm quality. Andrologia,   2022

25.  Li X. S., Li H. W., Cai D. B.,   Li P., Jin J. T., Jiang X. W., Li Z. H., Tian L. M., Chen G. B., Sun J. X.,   Bai W. B. Chronic oral exposure to cadmium causes liver inflammatory by NLRP3   inflammasome activation in pubertal mice. Food   and Chemical Toxicology, 2021, 148: 111944.

26.  Li X. S., Yao   Z. L., Yang D. C., Jiang X. W., Sun J. X., Tian L. M., Hu J., Wu. B. Y., Bai   W. B. Cyanidin-3-O-glucoside restores spermatogenic dysfunction in   cadmium-exposed pubertal mice via histone ubiquitination and mitigating   oxidative damage. Journal of Hazardous   Materials, 2020, 387: 121706.

27.  Li X. S.,   Zhang L., Peng Z. Y., Zhao Y. Q., Wu K. Y., Zhou N., Yan Y., Ramaswamy H. S.,   Sun J. X., Bai W. B. The impact of ultrasonic treatment on blueberry wine   anthocyanin color and its In-vitro anti-oxidant capacity. Food Chemistry., 2020, 333: 127455.

28.  Li   X. S., Yao Z. L.,   Jiang X. W., Sun J. X., Ran G. J., Yang X., Zhao Y. Q., Yan Y., Chen Z. S.,   Tian L. M., Bai W. B. Bioactive compounds from Cudrania tricuspidata: A   natural anticancer source. Critical   Reviews in Food Science and Nutrition., 2020, 60: 494-514.

29.  Li X. S., Guo J. T., Jiang X. W., Sun J. X., Tian L. M.,   Jiao R., Tang Y. G., Bai W. B. Cyanidin-3-O-glucoside protects against   cadmium-induced dysfunction of sex hormone secretion via the regulation of   hypothalamus-pituitary-gonadal axis in male pubertal mice. Food and Chemical Toxicology, 2019,   129: 13-21.

30.  Jiang X.   W., Zhu C. J., Li X. S.   (co-first author), Sun   J. X., Tian L. M., Bai W. B. Cyanidin-3-O-glucoside at low doses   protected against 3-chloro-1,2-propanediol induced testis injury and improved   spermatogenesis in male rats. Journal   of Agricultural and Food Chemistry., 2018, 66: 12675-12684.

31.  Jiang X.   W., Li X. S. (co-first author),   Zhu C. J., Sun J. X., Tian   L. M., Chen W., Bai W. B. The target cells of anthocyanins in   metabolic syndrome. Critical Reviews in   Food Science and Nutrition. 2019, 59: 921-946.

32.  Li X. S., Jiang X. W., Sun J. X., Zhu C. J., Bai W. B. Recent   advances of medical foods in China: The opportunities and challenges under   standardization. Food and Chemical   Toxicology, 2018, 119: 342-354.


主要著作

承担课题

[1] 国家自然科学基金青年基金,2026-2028,30万

[2] “十四五国家重点研发计划子课题,2024-202790

[3] 广州市重点研发计划,杨梅果渣高值化利用关键技术研发与应用,2025-2027100

[4] 广东省农村科技特派员项目,2024-202724

[5] 广东省基础与应用基础基金自然科学基金面上项目,花色苷膳食对高脂高果糖饮食诱导的代际遗传效应的干预研究,2023-202510

[6] 中国博士后科学基金面上资助,2023-20248

[7] 暨南大学附属第六医院科研启动项目,2022-202415


发明专利

[1] 白卫滨, 白顺, 李旭升, 陈嘉莉, 王晓涵, 蒋鑫炜, 蔡冬宝. 花色苷在冷冻保存精子中的应用、精子冷冻保存液, 2021-12-24, 中国, CN114223649A. 授权.

[2] 白卫滨, 焦睿, 袁洋冰, 李旭升, 李娅雯, 朱远琴, 梁灏甄. 花色苷衍生物用于制备治疗胆固醇代谢异常的药物的应用, 2021-10-12, 中国, CN113797217A. 授权.

[3] 白卫滨, 滕昭军, 孙建霞, 李旭升, 王超, 曾颖钰. 一种含花色苷果酒的护色发酵的方法, 2021-07-23, 中国, CN113549515A. 授权.

[4] 白卫滨, 杨达城, 蒋鑫炜, 田灵敏, 孙建霞, 李旭升, 陈嘉莉. 矢车菊素-3-O-葡萄糖苷在制备治疗和/或预防子宫内膜增生疾病的药物中的应用, 2020-08-04, 中国, CN111973611A. 授权.

[5] 白卫滨, 冉国敬, 孙建霞, 蒋鑫炜, 李旭升, 田灵敏, 焦睿. 一种利用中压液相色谱从桑葚中制备矢车菊素-3-葡萄糖苷的方法, 2018-07-03, 中国, CN109053833A 授权.


讲授课程

荣誉奖励

社会职务

[1] 中国果酒科创高层次人才

[2] 《食品研究与开发》第二、三届青年编委