欧阳东云，男，1967年生

理学博士，研究员，硕导、博导

籍贯：江西省赣州市兴国县

主要研究方向：炎症与炎症免疫药理

招生方向：细胞生物学（博士）、免疫学（硕士）

2001/09-2006/06, 中国科学院研究生院，昆明动物研究所，博士研究生

1986/09-1990/06，北京大学，生物系，本科

2015/10-至今，暨南大学，生科院免疫生物学系，研究员

2009/10-2015/09，暨南大学，生科院免疫生物学系，副研究员

2006/09-2009/09，暨南大学，生科院组织移植与免疫中心，助理研究员

(1)Wen-jing Bai^#, Chen-guang Li^#, Cheng-cheng Zhang^#, Li-hui Xu, Qiong-zhen Zeng, Bo Hu, Zhou Hong, Xian-hui He, Dong-yun Ouyang*, Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells, Front Immunol, 2018 Jan 5, 8:1919. （IF=5.511）

(2) Chen-guang Li^#, Liang Yan^#, Feng-yi Mai^#, Zi-jian Shi, Li-hui Xu, Yan-yun Jing, Qing-bing Zha, Dong-yun Ouyang, Xian-hui He*, Baicalin Inhibits NOD-Like Receptor Family, Pyrin Containing Domain 3 Inflammasome Activation in Murine Macrophages by Augmenting Protein Kinase A Signaling, Front Immunol, 2017 Oct 27, 8:1409. （IF=5.511）

(3) Yi-Dan Liang^#, Wen-Jing Bai^#, Chen-Guang Li^#, Li-Hui Xu, Hong-Xia Wei, Hao Pan, Xian-Hui He*, Dong-yun Ouyang*, Piperine suppresses pyroptosis and interleukin-1β release upon ATP triggering and bacterial infection, Front Pharmacol, 2016, 7: 390. （IF=4.400）

(4) Qing-Bing Zha^#, Hong-Xia Wei^#, Chen-Guang Li, Yi-Dan Liang, Li-Hui Xu, Wen-Jing Bai, Hao Pan, Xian-Hui He, Dong-Yun Ouyang*, ATP-induced inflammasome activation and pyroptosis is regulated by AMP-activated protein kinase in macrophages, Front Immunol, 2016, 7: 597. （IF=6.429）

(5) Mei-Yun Huang^#, Hao Pan^#, Yi-Dan Liang^#, Hong-Xia Wei, Li-Hui Xu, Qing-Bing Zha, Xian-Hui He*, Dong-Yun Ouyang*, Chemotherapeutic agent CPT-11 eliminates peritoneal resident macrophages by inducing apoptosis, Apoptosis, 2016, 21(2):130-142. （IF=3.833）

(6) Qiu-Ru Lin^#, Chen-Guang Li^#, Qing-Bing Zha^#, Li-Hui Xu, Hao Pan, Gao-Xiang Zhao, Dong-Yun Ouyang*, Xian-Hui He*, Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway, Toxicol Appl Pharmacol, 2016, 292: 56-64. （IF=3.791）

(7) Hao Pan^#, Li-Hui Xu^#, Mei-Yun Huang, Qing-Bing Zha, Gao-Xiang Zhao, Xiao-Feng Hou, Zi-Jian Shi, Qiu-Ru Lin, Dong-Yun Ouyang*, Xian-Hui He*, Piperine metabolically regulates peritoneal resident macrophages to potentiate their functions against bacterial infection, Oncotarget, 2015, 6(32): 32468-32483. （IF=5.008）

(8) Xiao-Feng Hou^#, Hao Pan^#, Li-Hui Xu, Qing-Bing Zha, Xian-Hui He, Dong-Yun Ouyang*, Piperine suppresses the expression of CXCL8 in lipopolysaccharide-activated SW480 and HT-29 cells via downregulating the mitogen-activated protein kinase pathways, Inflammation, 2015, 38(3): 1093-1102. （IF=2.618）

(9) Hao Pan, Li-Hui Xu, Dong-Yun Ouyang*, Yao Wang, Qing-Bing Zha, Xiao-Feng Hou, Xian-Hui He*, The second-generation mTOR kinase inhibitor INK128 exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW 264.7 cells, Inflammation, 2014, 37(3): 756-765. （IF=2.208）

        (10) Dong-Yun Ouyang, Li-Hui Xu, Xian-Hui He*, Yan-Ting Zhang, Long-Hui Zeng, Ji-Ye Cai, Shuai Ren, Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5, Autophagy, 2013, 9(1): 20-32. （IF=11.423)

1. 国家自然科学基金面上项目，81873064，中药活性成分吴茱萸碱增强微管蛋白乙酰化和炎症小体活化的药理作用及机制研究，2019/01-2022/12 ，57万元，主持。

2.国家自然科学基金面上项目,81773965,灯盏花乙素对NLRP3炎症小体活化和细胞焦亡的抑制作用及其机制研究, 2018/01-2021/12, 57万元, 参加。

3. 国家自然科学基金面上项目，81373423，胡椒碱通过mTOR信号调控固有免疫应答发挥抗炎作用的机制研究，2014/01-2017/12，65万元，主持。

4. 国家自然科学基金面上项目，81173604，葫芦素B通过持续激活cofilin干扰肌动蛋白细胞骨架动力学的抗肿瘤机制研究，2012/01-2015/12，58万元，主持。

世界中医药学会联合会中医药免疫专业委员会理事