个人信息 |
姓名: 苏玉斌 部门: 生命科学技术学院 性别: 男 职务: 院青工委副主任 职称: 副研究员(自然科学) 学位: 博士 毕业院校: 中山大学 联系电话: 电子邮箱: suyb7@jnu.edu.cn 办公地址: 暨南大学生命科学技术学院319室 通讯地址: 广州市黄埔大道西601号 邮编: 510632 传真: 荣誉奖励: |
联系方式suyb7@jnu.edu.cn
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个人简介苏玉斌,副教授,硕士生导师,主要从事细菌耐药与代谢等研究。目前以第一(含共一)和通讯(含共通)作者在Cell Metabolism、Science Advances 以及PNAS等SCI学术期刊发表文章20多篇。主持国家自然科学基金面上项目、青年项目、广东省自然科学基金面上项目等7项。入选2019年广东省100位博士博士后创新人物,获授权国家专利3项,获全国生物化学与分子生物学会“青年科学家论坛”二等奖。 学习经历2005.9-2009.7,集美大学生物工程学院(本科); 2009.9-2012.7,福建农林大学生命科学学院(硕士); 2012.9-2016.7,中山大学生命科学学院(博士)。 工作经历2016.7-2019.3,中山大学中山医学院,特聘副研究员; 2019.3-至今,暨南大学生命科学技术学院,副教授。 研究方向 细菌耐药与代谢调节研究
主要论文主要论文: (1)Ming Jiang#,Yu-bin Su#(Co-first author),Jin-Zhou Ye#, Hui Li#, Su-Fang Kuang, Jia-Han Wu, Shao-Hua Li, Xuan-Xian Peng, Bo Peng*.Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria.Science Advances, 2023, 9(10): eade8582. 中科院一区Top (2)Lv-yuan Fan, Zhi-yu Pan, Yi-lin Zhong, Juan Guo, Xu Liao, Rui Pang, Qing-qiang Xu, Guo-zhu Ye*, Yu-bin Su*(Co-corresponding author). L-glutamine sensitizes Gram-positive-resistant bacteria to gentamicin killing. Microbiology Spectrum, 2023,11(6): e0161923. 中科院一区Top (3) Zhi-yu Pan, Lv-yuan Fan, Yi-lin Zhong, Juan Guo, Xue-sa Dong, Xiao Xu, Chao Wang*, Yu-bin Su*. Quantitative proteomics reveals reduction in central carbon and energy metabolisms contributes to gentamicin resistance in Staphylococcus aureus. Journal of Proteomics, 2023, 277: 104849.中科院二区 (4) Lv-yuan Fan, Zhi-yu Pan, Liao Xu, Yi-lin Zhong, Juan Guo, Rui Pang, Xin-hai Chen, Guozhu Ye*, Yu-bin Su*. Uracil restores susceptibility of methicillin-resistantStaphylococcus aureus to aminoglycosides through metabolic reprogramming. Frontiers in Pharmacology, 2023, 14: 1133685.中科院二区Top (5) Juan Guo, Zhiyu Pan, Lvyuan Fan, Yilin Zhong, Rui Pang, Yu-bin Su*. Effect of three different amino acids plus gentamicin against methicillin-resistant Staphylococcus aureus. Infection and Drug Resistance, 2023,16:4741-4754. (6) Yu-Bin Su#, Xi-Kang Tang#, Ling-Ping Zhu, Ke-Xin Yang, Li Pan, Hui Li, Zhuang-GuiChen*. Enhanced biosynthesis of fatty acids contributes to ciprofloxacin resistance in Pseudomonas aeruginosa. Frontiers inMicrobiology, 2022, 13:845173. 中科院二区Top (7) Yi-Feng Huang, Yi Li, Jie-Ying Chen, Jia-Hui Lin, Lu Liu, Jin-Zhou Ye, Yu-Bin Su*.Promoting effect of Fe3+on gentamicin resistance in Escherichia coli. Biochemical and Biophysical Research Communications, 2022, 625:134-139. (8) Yu-xiong Lu#, Qing Yang#, Yu-bin Su#, Yin Ji#, Guo-bang Li, Xian-zhi Yang, Li-yan Xu, Zhao-liang Lu, Jia-jun Dong, Yi Wu, Jin-Xin Bei, Chao-yun Pan, Xiao-qiong Gu, Bo Li*. MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma. Cell Death & Disease, 2021, 12(6): 511.中科院一区Top (9) Yu-bin Su*, Su-fang Kuang, Jin-zhou Ye, Jian-jun Tao, Hui Li, Xuan-xian Peng, Bo Peng*. Enhanced biosynthesis of fatty acids is associated to the acquisition of ciprofloxacin resistance in Edwardsiella tarda. mSystems, 2021, 6(4):e0069421. 中科院二区Top (10) Yu-bin Su, Su-fang Kuang, Xuan-xian Peng, Hui Li*. The depressed P cycle contributes to the acquisition of ampicillin resistance in Edwardsiella piscicida.Journal of Proteomics, 2020, 212: 103562. 中科院二区 (11)Yu-bin Su#, Bo Peng#*, Hui Li#, Zhi-xue Cheng#, Tian-tuo Zhang, Jia-xin Zhu, Dan Li, Min-yi Li, Jin-zhou Ye, Chao-chao Du, Song Zhang, Xian-liang Zhao, Man-jun Yang, Xuan-xian Peng*. Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria.Proceedings of the National Academy of Sciences of the United States of America, 2018, 115(7): 1578-1587. 中科院一区Top (12) Bo Peng#,Yu-bin Su#, Hui Li#, Yi Han, Chang Guo, Yao-mei Tian, Xuan-xian Peng*. Exogenous alanine and/or glucose plus kanamycin kills antibiotic-resistant bacteria.Cell Metabolism, 2015, 21(2): 249-261.中科院一区Top (13) Yu-bin Su#, Bo Peng#, Yi Han, Hui Li, Xuanxian Peng*. Fructose restoressusceptibility of multidrug-resistant Edwardsiella tarda to kanamycin.Journal of Proteome Research, 2015, 14(3): 1612-1620. 9: 29.中科院二区 主要著作承担课题(1) 基于丙酮酸循环的乙醛酸循环在迟缓爱德华氏菌耐药中作用的研究,国家自然科学基金面上项目,42076095,2021-01至2024-12,58万元,在研; (2) 谷氨酸提高耐药菌对抗生素敏感性的分子机制研究,国家自然科学基金青年项目,31700119,2018-01至2020-12,22万元,已结题; (3) 脂肪酸生物合成在迟缓爱德华氏菌耐药中作用的机制研究,广东省自然科学基金面上项目,2022A1515010408, 2022-01至2024-12,10万元,在研; (4) 谷氨酸逆转大肠杆菌耐药性机制的研究,广东省自然科学基金面上项目,2019A1515012211,2019-10至2022-10,10万元,已结题; (5)谷氨酰胺逆转耐甲氧西林金黄色葡萄球菌耐药性机制的研究,广东市校(院)企联合资助项目, 2024A03J0379,2024-1至2025-12,20万元,在研; (6) 支链氨基酸提高斑马鱼抗迟缓爱德华氏菌感染的研究,广州市基础与应用研究项目,202102021206,2021-04至2023-04,5万元,已结题。 发明专利(1) 苏玉斌,杨俊,一种溶藻弧菌减毒活疫苗及其制备方法与应用,2022-05-17,中国,ZL202111301023.2 (2) 彭宣宪, 李惠, 苏玉斌, 一种提高抗生素清除病原菌的小分子代谢物, 2019-01-11, 中国, ZL201410847941.9 讲授课程1. 《生物科学研究方法》,本科课程,主讲 2.《微生物学》本科课程,共同授课 3.《生物技术应用》研究生课程,共同授课 荣誉奖励社会职务1.国家和省自然科学基金项目通讯评审专家; |