近十年的海外留学及工作经历，主要从事微生物资源开发利用及微生态相关领域研究，具体包括微生物群体感应调节与生物防控、肠道微生态与宿主免疫、水环境微生物资源开发利用、微生态制剂研发与替抗方案等。先后主持国家自然科学基金、国家重点研发计划子课题、广东省科技计划等各类型科研项目近二十项，发表SCI论文三十余篇。研究成果主要服务于水生态绿色可持续发展。

承担生科院及国际学院本科及研究生课程7门，其中全英课2门，多门课程在学院本科课程质量评估结果中位列前10%。主持广东省教学改革研究项目、暨南大学教学质量与教学改革工程等教学类项目5项。建设“港澳台侨特色金课”2门。获“第十届暨南大学教育教学成果奖”、 “暨南大学本科教学校长奖”、“暨南大学首届新任教师教学竞赛二等奖”、“暨南大学第六届本科课程全英语教学竞赛二等奖”等教学类奖项二十多项。

任广东省水产学会理事、广东省/企业农村科技特派员、广州市农村科技特派员、广东省休闲渔业与垂钓协会智库专家。

(1) 2010-12至2011-12, 香港浸会大学, 博士后

(2) 2008-10至2010-10, 法国巴黎第11大学, 博士后

(3) 2004-9至2008-2, 韩国明知大学, 生物学, 博士

(4) 2002-9至2004-8, 韩国明知大学, 环境工程与生物技术, 硕士

2012-10至现在, 暨南大学, 生命科学技术学院，生态学系/水生生物研究中心, 教授

微生物群体感应调节与生物防控、肠道微生态与宿主免疫、水环境微生物资源开发利用、微生态制剂研发与替抗方案等。

（1）      Yunwen Bi^†, Hao An^†, Zhewei Chi^†, Zhongheng Xu, Yuan Deng, Yuxian Ren, Rui Wang, Xinyi Lu, Jia Guo*, Ren Hu*, Marie-Joelle Virolle* and Delin Xu*. (2024) The acetyltransferase SCO0988 controls positively specialized metabolism and morphological differentiation in the model strains Streptomyces coelicolor and Streptomyces lividans. Frontiers in Microbiology, 15:1366336. DOI: 10.3389/fmicb.2024.1366336

（2）      Miao Cui, Gaojun Zheng, Xin Wu, Jiaying Zhang, Zibin Wang, Zhicong Pang, Shixu Wang, Ren Hu*, Delin Xu*. (2024) Microplastics’ vector effect on Co-bioaccumulation of it and polychlorinated biphenyls in Crassostrea hongkongensis. Ecotoxicology and Environmental Safety, 285 (2024) 117119.

（3）      Ganxing Liu†, Hao An†, Lei Tang†, Zhewei Chi, Yunwen Bi, Zeqi Ye, Haiming Zhao, Lei Xiang, Naixian Feng*, Cehui Mo*, Delin Xu*. (2024) Activated DBP degradation and relevant signal transduction path via quorum sensing autoinducers in Streptomyces sp. SH5. Journal of Hazardous Materials. 466: 133571.

（4）       Qiting Liang†, Ganxing Liu†, Zheng Guo†, Yuting Wang, Zhongheng Xu, Yuxian Ren, Qizhong Zhang^*, Miao Cui^*, Xinqing Zhao^*, Delin Xu^* (2022) Application of potential probiotic strain Streptomyces sp. SH5 on anti-Aeromonas infection in zebrafish larvae. Fish & Shellfish Immunology. 127: 375–385.

（5）       Miao Cui^*, Zibin Wang, Yongchun Yang, Ru Liu, Min Wu, Yujie Li, Qizhong Zhang and Delin Xu^* (2022) Comparative Transcriptomic Analysis Reveals the Regulated Expression Profiles in Oreochromis niloticus in Response to Coinfection of Streptococcus agalactiae and Streptococcus iniae. Frontiers in Genetics. doi: 10.3389/fgene.2022.782957

（6）       Yunwen Bi, Ganxing Liu, Qiushi Yu, Qiting Liang, Zhongheng Xu, Miao Cui^*, Qizhong Zhang*, Delin Xu^*（2021）Anti-Vibrio dibutyl phthalate from marine-derived Streptomyces sp. S073. Research in Veterinary Science. 140: 198-202

（7）   Tinglong Hou^†, Delin Xu^†, Miao Cui, Huiru Liu, Yaowu Fu, Lingli Zhang, Lei Tang, Yanmeng Liu, Qizhong Zhang^* (2020) The transcriptional factor GATA-4 negatively regulates Hsp70 transcription in Crassostrea hongkongensis. Molecular Biology Reports. 47:7107–7114. DOI: 10.1007/s11033-020-05778-9

（8）       Jun Zhang†, Qiting Liang†, Zhongheng Xu, Miao Cui, Qizhong Zhang1, Sonia Abreu, Michelle David, Clara Lejeune, Pierre Chaminade, Marie-Joelle Virolle, Delin Xu^* (2020) The inhibition of antibiotic production in Streptomyces coelicolor over-expressing the TetR regulator SCO3201 is correlated with changes in the lipidome of the strain. Frontiers in Microbiology. doi: 10.3389/fmicb.2020.01399

（9）       Luoqiang Zhang^†, Delin Xu^†, Feifei Wang, Qizhong Zhang (2019) Antifungal activity of Burkholderia sp. HD05 against Saprolegnia sp. by 2-pyrrolidone-5-carboxylic acid. Aquaculture. 511:634198

（10）   Miao Cui, Huijie Zhang, Jingjing Li, Ru Liu, Min Wu, Delin Xu^*, Qizhong Zhang^* (2019) Differential PCR detection of Streptococcus agalactiae and Streptococcus iniae in tilapia (Oreochromis niloticus) by a single primer pair. Journal of Fish Diseases. 42(8):1211-1216.

（11）   Mingxia Yang, Jun Zhang, Qiting Liang, Guanxin Pan, Jiachang Zhao, Miao Cui, Xinqing Zhao, Qizhong Zhang, Delin Xu* (2019) Antagonistic activity of marine Streptomyces sp. S073 on pathogenic Vibrio parahaemolyticus. Fisheries Science. 85:533–543

（12）   Delin Xu^†, Di Wang^†, Miao Cui, Qizhong Zhang^* (2018) The purine-rich element-binding protein ChPur-α negatively regulates Hsc70 transcription in Crassostrea hongkongensis. Cell Stress and Chaperones. 23: 91-100

（13）   Huiru Liu^†, Delin Xu^†, Miao Cui, Tinglong Hou, Qizhong Zhang （2018）The transcriptional factor YB-1 positively regulates Hsc70 transcription in Crassostrea hongkongensis. Biochemical and Biophysical Research Communications. 495: 2404-2409

（14）   Lingli Zhang, Delin Xu, Miao Cui, Lei Tang, Tinglong Hou, Qizhong Zhang (2018) The guanine nucleotide-binding protein α subunit protein ChGnaq positively regulates Hsc70 transcription in Crassostrea hongkongensis. Biochemical and Biophysical Research Communications. 499: 215-220

（15）   Delin Xu†, Qin Yang†, Miao Cui and Qizhong Zhang (2017) The novel transcriptional factor HP1BP3 negatively regulates Hsp70 transcription in Crassostrea hongkongensis. Scientific Reports. | 7: 1401 | DOI:10.1038/s41598-017-01573-y

（16）   Lan Yan, Qizhong Zhang, Marie-Joelle Virolle, Delin Xu* (2017) In conditions of over-expression, WblI, a WhiB-like transcriptional regulator, has a positive impact on the weak antibiotic production of Streptomyces lividans TK24. PLoS One. https://doi.org/10.1371/journal.pone.0174781

（17）   Zongyu Miao†, Delin Xu^†, Miao Cui, Qizhong Zhang (2016) High mobility group protein DSP1 negatively regulates HSP70 transcription in Crassostrea hongkongensis. Biochemical and Biophysical Research Communications. 474: 634-639

（18）   Delin Xu, Miao Cui and Qizhong Zhang (2016) Transcriptional Activity of Full-Length and Truncated Metallothionein Promoters of Crassostrea hongkongensis in Response to Metal Stress. Journal of Shellfish Research. 35(1): 83-89

（19）   Delin Xu†, Bo Yu, Yan Zhang, Miao Cui and Qizhong Zhang (2015) Metallothionein Protein Expression of Crassostrea hongkongensis in Response to Cadmium Stress. Journal of Shellfish Research. 34(2):311-318

（20）   Delin Xu†, Paul Waack, Qizhong Zhang, Sebastiaan Werten, Winfried Hinrichs, Marie-Joelle Virolle (2014) Structure and regulatory targets of SCO3201, a highly promiscuous TetR-like regulator of Streptomyces coelicolor M145. Biochem Biophys Res Commun. 450 : 513–518.

（21）   Ammaiyappan Selvam, Delin Xu, Zhenyong Zhao, Jonathan W.C. Won (2012) Fate of tetracycline, sulfonamide and fluoroquinolone resistance genes and the changes in bacterial diversity during composting of swine manure. Bioresource Technology. 126: 383-390

（22）   Delin Xu^†, Nicolas Seghezzi^†, Catherine Esnault and Marie-Joelle Virolle (2010) Repression of antibiotic production and sporulation in Streptomyces coelicolor by overexpression of a TetR family transcriptional regulator. Appl. Environ. Microbiol.76 (23): 7741-53

（23）   Delin Xu^†, Tae-Jong Kim^†, ZY Park, SK Lee, SH Yang, Hyung-Jin Kwon and Joo-Won Suh (2009) A DNA-binding factor, ArfA, interacts with the bldH promoter and affects undecylprodigiosin production in Streptomyces lividans. Biochem Biophys Res Commun. 379: 319-23

（24）   Delin Xu, Hyung-Jin Kwon and Joo-Won Suh (2008) S-Adenosylmethionine induces BldH and activates secondary metabolism by involving the TTA-codon control of bldH expression in Streptomyces lividans. Arch Microbiol. 189: 419-26

（25）   Su-Kyoung Shin^†, Delin Xu^†, Hyung-Jin Kwon & Joo-Won Suh (2006) S-Adenosylmethionine activates adpA transcription and promotes streptomycin biosynthesis in Streptomyces griseus. FEMS Microbio Lett 259: 53-59

(1)国家自然科学基金（面上）：链霉菌SH5肠道定植及群感效应调节机制（编号：32271568），2023.01 ~ 2026.12

(2)广东省自然科学基金：链霉菌SH5防控嗜水气单胞菌感染的益生作用机制（编号：2023A1515012806）, 2023.01~2025.12

(3)国家重点研发计划子课题：基于牧食作用调控的富营养化水体生物修复技术研究(编号：2022YFE0122100), 2023.01~2024.12

(4)国家自然科学基金重点项目--子课题：微生物介导作物吸收累积新兴有机污染物的环境生物地球化学机制（编号：42030713），2021.01 ~ 2025.12

(5)广州市科技计划项目（基础与应用基础）：潜在益生链霉菌株S073防治弧菌病机制的研究（编号：202102080372），2021.04~2023.03

(6)广东省科技计划项目：广东特色水产品生态养殖技术集成与示范指导项目（No.[2019]170），2019.10~2021.10

(7)广东省自然科学基金：铁载体介导的海洋链霉菌S073防控弧菌病机制的研究（2019A1515011791）, 2019.10~2022.9

(8)广东省自然科学基金：乙酰转移酶SCO0988调控链霉菌抗生素合成的机理（2018A030313578）, 2018.10~2021.10

(9)广东省自然科学基金：弧菌特异性抑制剂的筛选及防治弧菌病效果的研究（编号：2015A030313319）, 2015.10~2018.10

(10)国家自然科学基金（青年）：TetR家族蛋白，SCO3201，在天蓝色链霉菌和变铅青链霉菌中下游调控靶基因的鉴定及功能分析 (编号：31300046), 2014.01 ~ 2016.12

(11)广东省自然科学基金：链霉菌中对一TetR家族转录调控因子调控目标基因的鉴定（编号：S2013010013705), 2013.10 ~ 2015.10

(12)农业部南海渔业资源开发利用重点实验室开放基金：水霉拮抗放线菌的筛选及预防水霉感染效果研究（编号：LSF2013-07), 2013.08 ~ 2015.07

1.       国家知识产权局-发明专利：一种同时快速检测无乳链球菌和海豚链球菌的引物及其应用。证书号:3321709

2.       国家知识产权局-发明专利：一株海洋链霉菌及其在防控嗜水气单胞菌感染水生动物中的应用。专利号:ZL 2021 1 1640257.X

广东省水产学会理事。Frontiers in Environmental Sciences期刊编委，Aquaculture、Frontiers in Microbiology、Journal of Fish Disease等学术期刊审稿人。广东省/企业农村科技特派员，广州市农村科技特派员，广东省休闲渔业与垂钓协会智库专家。