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姓名: 白杰云

部门: 信息科学技术学院

直属机构: 电子工程系

性别:

职务:

职称: 讲师

学位: 博士

毕业院校: 哈尔滨工业大学

联系电话: 18620711783

电子邮箱: bai_jieyun@126.com

办公地址: 南海楼730

通讯地址:

邮编:

传真:

荣誉奖励:

联系方式

微信:aspirerabbit

邮箱:bai_jieyun@126.com

个人简介

白杰云,硕士生导师,隶属于暨南大学广东省中医药信息化重点实验室智慧医疗电子技术研究中心,2017年毕业于哈尔滨工业大学,2018年在新西兰奥克兰大学生物工程研究所从事博士后研究工作,2019年至今就职于暨南大学,从事智能仪器与现代医疗仪器、人工智能与医疗机器人、机器学习与医疗大数据、生物系统建模与仿真等研究工作。目前,主持国家自然科学基金青年项目1项,参与国家自然基金面上项目1项,参与国家重点研发计划“数字诊疗装备研发”重点专项3项。以第一作者/通讯作者发表论文30余篇,申请发明专利5项,获得软件著作权1项。学术兼职:广东省生物医学工程学会智慧医疗分会委员。

学习经历

2013 年 9 月-2017 年 12 月,哈尔滨工业大学(985),计算机应用技术(国家重点学科&双一流学科),博士; 

工作经历

2018 年 1 月-2019 年 1 月,奥克兰大学(QS Ranking: 82),奥克兰生物工程研究所,博士后; 
2019 年 3 月-至今,暨南大学,信息科学技术学院,讲师,硕士生导师;


研究方向

人工智能与医疗机器人、机器学习与医疗大数据、智能仪器与现代医疗仪器

招生意向

白杰云,暨南大学信息学院硕士研究生导师,隶属于陆尧胜的智慧医疗实验室和广东省智慧医疗电子信息工程技术研究中心。2017年毕业于哈尔滨工业大学,师从王宽全教授,2018年1月至2019年2月在新西兰奥克兰大学生物工程研究所Jichao Zhao心房实验室从事博士后工作,2019年至今就职于暨南大学信息科学技术学院,从事智能仪器与现代医疗仪器、人工智能与医疗机器人、机器学习与医疗大数据、生物系统建模与仿真等研究工作。曾荣获哈尔滨工业大学“十佳英才”提名奖、哈尔滨工业大学优秀毕业生、黑龙江省三好学生、电科十四所奖学金、华为奖学金、工信部创新一等奖学金、国家奖学金等称号。目前,主持国家自然科学基金青年项目1项,参与国家自然基金面上项目1项,参与国家重点研发计划“数字诊疗装备研发”重点专项2项。以第一作者发表论文20余篇,申请发明专利5项,获得软件著作权1项,是Scientific reports、Frontiers in physiology、Computers in Biology and Medicine、international journal of molecular sciences,Plos one等期刊的评阅人。
 
长期招收电子信息相关专业的硕士研究生。研究方向包括智能仪器与现代医疗仪器、人工智能与医疗机器人、机器学习与医疗大数据等;先进的研究课题得到了国家自然科学基金和重点研发计划”数字诊疗装备研发“重点专项的支持,经费充足;实验室拥有包括进行相关算法研究的GPU服务器2台和医疗设备开发相关的设备(如:胎心监护和产时超声)等;具有产-学-研一条龙平台:包括广东省智慧医疗电子信息工程技术研究中心、暨南大学电子工程系智慧医疗实验室、多家合作医院(包括暨南大学附属医院等)和莲印公司;实验室提供国内外学术交流的机会(如参加Computing in Cardiology, International Engineering in Medicine and Biology Conference等国际会议)和研究成果奖学等。
合作的各家医院(包括暨南大学附属医院)
 
长期招收临时参与科学研究的本科生,项目包括:1、胎心监护仪研发;2、产科超声设备开发;3、胎心电信号处理与算法研发;4、产科超声影像处理与算法研发;5、医疗数据库的建立与数据清洗等。每个项目给予学生的经费支持为3000-5000元,项目开发周期为3-5个月,获得专利、软件、研究论文等成果共享,招收本科生面向全校本科生。  
欢迎动手能力强,创新意识和专业基础良好,诚实守信、踏实、有毅力的本科生来本团队进行实习或做毕业设计(长期有效)。要求至少掌握一门编程语言,包括C/C++, Matlab, Python等。尤其欢迎英语基础好的学生。
 
成果履历:https://www.researchgate.net/profile/Jieyun_Bai


主要论文

Peer-reviewed Journal Articles

Bai, Jieyun*; Lu, Y., Zhu, Y., Wang, H*., Yin, D., Zhang, H., Franco, D., & Zhao, J*. Understanding PITX2-Dependent Atrial Fibrillation Mechanisms through Computational Models[J]. International Journal of Molecular Sciences, 2021, 22(14): 7681. 

Bai, Jieyun*; Zhu, Yijie; Lo, Andy; Gao, Meng*; Lu, Yaosheng*; Zhao, Jichao; Zhang, Henggui; In Silico Assessment of Class I Antiarrhythmic Drug Effects on Pitx2-Induced Atrial Fibrillation: Insights from Populations of Electrophysiological Models of Human Atrial Cells and Tissues, International Journal of Molecular Sciences, 2021, 22(3):0-22031265. SCIE. 

Mujun Liu; Yaosheng Lu; Shun Long; Bai, Jieyun*; Wanmin Lian*; An attention-based CNN-BiLSTM hybrid neural network enhanced with features of discrete wavelet transformation for fetal acidosis classification, Expert Systems with Applications, 2021, 186(30):0-115714. SCIE. 

Zeng, Rongdan; Lu, Yaosheng; Long, Shun; Wang, Chuan; Bai, Jieyun*; Cardiotocography signal abnormality classification using time-frequency features and Ensemble Cost-sensitive SVM classifier, Computers in Biology and Medicine, 2021, 130(130):0-104218. Andy Lo, 

Jieyun Bai, Gladding, P. A., Fedorov, V. V., & Zhao, J. Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels [J]. Philosophical Transactions of The Royal Society A Mathematical Physical and Engineering Sciences, 2020, 378(2173):20190557

Jieyun Bai, Andy Lo, Gladding, P. A., Stiles, M. K., Fedorov, V. V., & Zhao, J. In silico investigation of the mechanisms underlying atrial fibrillation due to impaired Pitx2[J]. PLoS computational biology, 2020, 16(2): e1007678.

Jieyun Bai, Yaosheng Lu, Henggui Zhang. In silico study of the effects of anti-arrhythmic drug treatment on sinoatrial node function for patients with atrial fibrillation[J]. Scientific Reports, 2020, 10(1): 1-14.

Jieyun Bai, Yaosheng Lu, Andy Lo, Jichao Zhao, Henggui Zhang. Pitx2 upregulation increases the risk of chronic atrial fibrillation in a dose-dependent manner by modulating IKs and ICaL–insights from human atrial modelling[J]. Annals of Translational Medicine, 2020;8(5):191.
Jieyun Bai, Yaosheng Lu, Andy C.Y. Lo, Jichao Zhao and Henggui Zhang. Proarrhythmia in the p.Met207Val PITX2c-linked familial atrial fibrillation-insights from modelling. Frontiers in Physiology, 2019;
Cuiping Liang, Kuanquan Wang, Qince Li, Jieyun Bai, and Henggui Zhang. Influence of the distribution of fibrosis within an area of myocardial infarction on wave propagation in ventricular tissue. Scientific Reports, 2019;
Jieyun Bai, Gladding, P. A., Stiles, M. K., Fedorov, V. V., & Zhao, J. (2018). Ionic and cellular mechanisms underlying TBX5/PITX2 insufficiency-induced atrial fibrillation: Insights from mathematical models of human atrial cells. Scientific Reports, 8 (1).
Jieyun Bai, Kuanquan Wang, Qince Li, Yongfeng Yuan, Henggui Zhang. Pro-arrhythmogenic effects  of  CACNA1C  G1911R  mutation  in  human  ventricular  tachycardia:  insights  from cardiac multi-scale models. Scientific Reports, 2016
Jieyun Bai, Yinli Ren, Kuanquan Wang, Henggui Zhang. Mechanisms underlying the emergence    of    post-acidosis    arrhythmia    at    the    tissue    level:    A     theoretical study.  Frontiers in Physiology, 2017
Jieyun Bai, K Wang, Y Liu, Y Li, C Liang, G Luo, S Dong, Y Yuan, H Zhang. Computational cardiac modeling reveals mechanisms of ventricular arrhythmogenesis in long QT syndrome type 8: CACNA1C R858H mutation linked to ventricular fibrillation. Frontiers in Physiology, 2017
Jieyun Bai, K Wang, H Zhang. Potential Pathogenesis Discovery of Arrhythmia Based on Cardiac Electrophysiological Models: Research Progress. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 43 (2), 128-140
Jieyun Bai, S Xie, K Wang, Y Yuan. Simulation Research on Early Afterdepolarizations-mediated Ventricular Fibrillation Based on a Heart Model. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 42 (10), 955-961
Huanling Liu, Jieyun Bai, Kuanquan Wang, Q Li, Y Yuan. Simulation Study of Ventricular Arrhythmia in Post Acidosis. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 43 (7), 716-724.
Conference Proceedings
Jieyun Bai, Kuanquan Wang, Henggui Zhang. Ca2+/calmodulin-dependent protein kinase modulation of torsade de pointes arrhythmogenesis and identification of targeted sites of antiarrhythmic therapy in human Timothy Syndrome arising from a new CACNA1C mutation. The 26th Great Wall International Congress of Cardiology, Journal of the American College of Cardiology, 2015, 66(16), C75-C75. 
Jieyun Bai, Kuanquan Wang, Henggui Zhang. Triggered Activity in Human Heart Is Determined by Sarcoplasmic Reticulum Calcium Load in Post Acidosis. The 27th  Great Wall International Congress of Cardiology, Journal of the American College of Cardiology, 2016, 68(18), C14-C15. 
Jieyun Bai, Kuanquan Wang, Henggui Zhang. Pro-arrhythmic Effects of Calmodulin Kinase II (CaMKII) in Timothy Syndrome Arising from A CACNA1C Mutation. The 20th Word Congress on Heart Disease, Cardiology, 2015, 131, 303-303. 
Jieyun Bai, Kuanquan Wang, Henggui Zhang. Multi-scale Cardiac Modelling Reveal Tachyarrhythmias Induced by Abrupt Rate Accelerations in Long QT Syndrome. The proceedings of Bioinformatics and Biomedicine (BIBM), 2016 (pp. 1439-1444).
Jieyun Bai, Kuanquan Wang, Xiangyun Bai, Yongfeng Yuan, Henggui Zhang. Pro-arrhythmic Effects of Increased Late Sodium Current in Failing Human Heart. Proceedings of Computing in Cardiology, 2014 (pp. 857-860).
Jieyun Bai, Kuanquan Wang, Qince Li, Yinhui Li, Henggui Zhang. Effects of early afterdepolarizations on ventricular tachycardia in human heart. Proceedings of Computing in Cardiology, 2015 (pp. 857-860).
Jieyun Bai, Kuanquan Wang, Gongning Luo, Henggui Zhang. In Silico Investigation of Spontaneous Calcium Release on Premature Ventricular Contractions in Human Ventricles. Proceedings of Computing in Cardiology, 2016 (43).
Huanling Liu, Kuanquan Wang, Jieyun Bai, Suyu Dong, Henggui Zhang. Calcium Calmodulin Dependent Protein Kinase II (CaMKII) Contribute to Arrhythmias after Acidosis: A Simulation Study. Proceedings of Computing in Cardiology, 2016 (43).
Jieyun Bai, Yaosheng Lu, Andy C.Y. Lo, Jichao Zhao. PITX2 overexpression leads to atrial electrical remodeling linked to atrial fibrillation. Proceedings of Computing in Cardiology, 2019
Andy C.Y. Lo, Jieyun Bai, Patrick Gladding, Jichao Zhao. The Ionic Mechanisms of Triggered Atrial Activity under a TBX5-Driven Regulatory Network. Proceedings of Computing in Cardiology, 2019
Jieyun Bai, Yaosheng Lu, Tao Song, Kuanquan Wang, Henggui Zhang. In Silico Investigation of the CACNA1C N2091S mutation in Timothy Syndrome. Proceedings of Computing in Cardiology, 2019
Jieyun Bai, Yaosheng Lu, Roshan Sharma, Jichao Zhao. In silico Screening of the Key Electrical Remodelling Targets in Atrial Fibrillation-induced Sinoatrial Node Dysfunction. Proceedings of Computing in Cardiology, 2019
Jieyun Bai, Yijie Zhue, Andy Lo, Yaosheng Lu, Jichao Zhao. In Silico Assessment of Genetic Variation in PITX2 Reveals the Molecular Mechanisms of Calcium-Mediated Cellular Triggered Activity in Atrial Fibrillation. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2353-2356.


主要著作

件著作权
心脏电生理仿真软件.登记号:2019R11L342355


承担课题

国家自然科学基金青年项目(2020-2022):基于多尺度心脏计算模型的Timothy综合征发病机制研究(主持);
国家重点研发计划”数字诊疗装备研发“重点专项(2020-2022):分娩监护仪关键技术及其产业化研发(参与);
国家重点研发计划”数字诊疗装备研发“重点专项(2017-2020):高可信强智能的心脑血管疾病诊疗服务解决方案(参与);
国家自然科学基金面上项目(2016-2019):个体化的虚拟生理心室建模与仿真方法研究(参与)。

发明专利

白杰云,陆尧胜,杨仁桓. 一种人类心房数学模型的构建方法[P]. 广东省:CN110459262A,2019-11-15. 
白杰云,陆尧胜,杨仁桓. 窦房结虚拟生理组织的构建方法、存储介质和计算设备[P]. 广东省:CN110310744A,2019-10-08.
王宽全,白杰云,张恒贵,袁永峰,李钦策,谢松君. 一种用于分析CaMKII致室性心律失常的仿真系统[P]. 黑龙江:CN106777934A,2017-05-31.
王宽全,白杰云,张恒贵,袁永峰,李钦策. 一种基于多尺度心脏Thimthy综合症发病机制的建模方法[P]. 黑龙江:CN105512489A,2016-04-20

讲授课程

  • 微机原理与接口技术

  • C语言高级程序设计

  • 数据结构

  • 算法分析与设计

  • 数字图像处理


荣誉奖励

社会职务

广东省生物医学工程学会智慧医疗分会委员. 

Frontiers in Physiology 客作编辑