He Kaiyin, M.D., Ph.D.

Attending Physician, Doctoral Supervisor, Master's Supervisor

Professional Affiliations:
Member of the Fatty Liver Professional Committee, Guangdong Health Management Association
Member of the Nutrition Education and Health Promotion Committee, Guangdong Nutrition Society
Member of the Maternal and Child Nutrition Committee, Guangdong Nutrition Society
Member of the Parenteral and Enteral Nutrition Branch, Guangdong Medical Association
Member of the Nutrition Management Professional Committee, Guangdong Hospital Association
Member of the Digestion and Nutrition Professional Committee, Guangdong Research Hospital Society

Clinical Expertise:
Specialized in the prevention and management of gastrointestinal disorders (e.g., IBS, SIBO, chronic constipation/diarrhea, IBD), weight management (evidence-based weight loss/gain), comprehensive care for chronic metabolic diseases (including NAFLD, type 2 diabetes, PCOS, Hashimoto’s thyroiditis, hyperuricemia), and nutritional support for oncology patients (during chemotherapy/perioperative periods).

Research Achievements:
Has led or participated in 4 research projects funded by the National Natural Science Foundation of China and provincial grants. Published over 10 peer-reviewed articles in Chinese and international journals.

Bachelor of Medicine: Clinical Medicine (International School), Jinan University

Master of Science: Clinical Nutrition, University of Nottingham, UK

Doctor of Philosophy: Digestive Internal Medicine, Jinan University

2016-present: Department of Clinical Nutrition, the First Affiliated Hospital of Jinan University

1. He K, Guo LL, Tang H, Peng X, Li J, Feng S, Bie C, Chen W, Li Y, Wang M, Tang S. A Freshwater Fish-Based Diet Alleviates Liver Steatosis by Modulating Gut Microbiota and Metabolites: A Clinical Randomized Controlled Trial in Chinese Participants With Nonalcoholic Fatty Liver Disease. Am J Gastroenterol. 2022 Oct 1;117(10):1621-1631. doi: 10.14309/ajg.0000000000001885. Epub 2022 Jun 17. PMID: 35973188; PMCID: PMC9531978.

2. He K, Huang H. The Significant Role of Alcohol in the Relationship between C-Reactive Protein and Self-Reported Osteoarthritis. J Nutr. 2024 Feb;154(2):600-609. doi: 10.1016/j.tjnut.2024.01.009. Epub 2024 Jan 12. PMID: 38219865.

3. He K, Pang T, Huang H. The relationship between depressive symptoms and BMI: 2005-2018 NHANES data. J Affect Disord. 2022 Sep 15;313:151-157. doi: 10.1016/j.jad.2022.06.046. Epub 2022 Jun 24. PMID: 35753497.

4. He K, Li Y, Guo X, Zhong L, Tang S. Food groups and the likelihood of non-alcoholic fatty liver disease: a systematic review and meta-analysis. Br J Nutr. 2020 Jul 14;124(1):1-13. doi: 10.1017/S0007114520000914. Epub 2020 Mar 6. PMID: 32138796; PMCID: PMC7512147.

5. Huang H, He K. The association between dietary fiber intake and severe headaches or migraine in US adults. Front Nutr. 2023 Jan 4;9:1044066. doi: 10.3389/fnut.2022.1044066. PMID: 36687687; PMCID: PMC9846638.

6. Ye YB , He KY , Li WL , Zhuo SY , Chen YM , Lu W , Wu SL , Liu J , Li YB , Zeng FF . Effects of daidzein and genistein on markers of cardiovascular disease risk among women with impaired glucose regulation: a double-blind, randomized, placebo-controlled trial. Food Funct. 2021 Sep 7;12(17):7997-8006. doi: 10.1039/d1fo00712b. Epub 2021 Jul 15. PMID: 34263280.

7. Zhang S, Chen S, He K, Liu J, Su X, Li W, Ma J, Cheng C, Ouyang R, Mu Y, Zheng L, Cai J, Feng Y, Zeng F, Peng L, Ye Y. The Interaction of Dietary Patterns and Genetic Variants on the Risk of Cardiovascular Diseases in Chinese Patients with Type 2 Diabetes. Mol Nutr Food Res. 2023 Nov;67(22):e2300332. doi: 10.1002/mnfr.202300332. Epub 2023 Sep 15. PMID: 37712112.

8. Li J, Li Y, Feng S, He K, Guo L, Chen W, Wang M, Zhong L, Wu C, Peng X, Tang S. Differential Effects of Dietary White Meat and Red Meat on NAFLD Progression by Modulating Gut Microbiota and Metabolites in Rats. Oxid Med Cell Longev. 2022 Aug 5;2022:6908934. doi: 10.1155/2022/6908934. PMID: 36035222; PMCID: PMC9410827.

(1) Basic and Applied Basic Research Project (Young Doctor setting off direction), Basic research, SL2024A04J00827, Research on the effect and mechanism of grass carp protein hydrolysate on non-alcoholic fatty liver disease based on SSA1-NF-κB signaling pathway; 2025-01 to 2026-12, 50,000 yuan, in research, host

(2) Danone Nutrition Center, Horizontal project, DIC2023-08, The effects of healthy liver diet intervention on liver fat, glucose and lipid metabolism and intestinal flora in patients with non-alcoholic fatty liver disease, 2024-01 to 2025-12, 200 000 yuan, in research, participanted

(3) Jinan University, Basic Research, 21622317, The potential mechanism of Fusobacterium nucleatum promoting VEGFA expression to affect the progression of colorectal cancer, 2022-October to 2024-10, 90 000 yuan, In Research, PI